Composite tissue allotransplantation

Plastic and Reconstructive Surgery

Volumn 124, Issue SUPPL. 6, 2009, Pages

  Siemionow, Maria Z ^a   Kulahci, Yalcin ^a   Bozkurt, Mehmet ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOTRANSPLANTATION; ANIMAL; BIOLOGICAL MODEL; FACE; FORECASTING; HUMAN; METHODOLOGY; REVIEW;

ANIMALS; FACE; FORECASTING; HUMANS; MODELS, BIOLOGICAL; TRANSPLANTATION, HOMOLOGOUS;

EID: 75549091469     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0b013e3181bf8413     Document Type: Review

References (85)

1. Gordon CR, Nazzal J, Lozano-Calderan SA, et al. From experimental rat hindlimb to clinical face composite tissue allotransplantation: Historical background and current status. Microsurgery 2006;26:566-572.
2. Gorantla V, Maldonado C, Frank J, Barker JH. Composite tissue allotransplantation (CTA): Current status and future insights. Eur J Trauma 2001;27:267-274.
3. Siemionow M, Ozer K. Advances in composite tissue allograft transplantation as related to the hand and upper extremity. J Hand Surg (Am.) 2002;27:565-580.
4. Siemionow M, Papay F, Kulahci Y, et al. Coronal-posterior approach for face/scalp flap harvesting in preparation for face transplantation. JReconstr Microsurg. 2006;22:399-405.
5. Siemionow M, Bozkurt M, Kulahci Y. Current status ofcom- posite tissue allotransplantation. Handchir Mikrochir Plast Chir. 2007;39:145-155.
6. Gilbert R. Transplant is successful with a cadaver forearm. Med Trib Med News 1964;5:23-25.
7. Dubernard JM, Owen E, Herzberg G, et al. Human hand allograft: Report on first 6 months. Lancet 1999;353:1315-1320. (Pubitemid 29178782)
8. Whitaker IS, Duggan EM, Alloway RR, et al. Composite tissue allotransplantation: A review of relevant immunological issues for plastic surgeons. J Plast Reconstr Aesthet Surg. 2008; 61:481-492.
9. Francois CG, Breidenbach WC, Maldonado C, et al. Hand transplantation: Comparisons and observations of the first four clinical cases. Microsurgery 2000;20:360-371.
10. Hettiaratchy S, Randolph MA, Petit F, Lee WP, Butler PE. Composite tissue allotransplantation: A new era in plastic surgery? Br J Plast Surg. 2004;57:381-391.
11. Petit F, Minns AB, Dubernard JM, Hettiaratchy S, Lee WP. Composite tissue allotransplantation and reconstructive surgery: First clinical applications. Ann Surg. 2003;237:19-25.
12. Lanzetta M, Petruzzo P, Vitale G, et al. Human hand trans plantation: What have we learned? Transplant Proc. 2004;36:664-668.
13. Levi DM, Tzakis AG, Kato T, et al. Transplantation of the abdominal wall. Lancet 2003;36:2173-2176.
14. Hofmann GO, Kirschner MH, Wagner FD, Brauns L, Gon- schorek O, Bühren V. Allogeneic vascularized transplantation of human femoral diaphyses and total knee joints: First clinical experiences. Transplant Proc. 1998;30:2754-2761.
15. Hofmann GO, Kirschner MH. Clinical experience in allo- geneic vascularized bone and joint allografting. Microsurgery 2000;20:375-383.
16. Guimberteau JC, Baudet J, Panconi B, Boileau R, Potaux L. Human allotransplant of a digital flexion system vascularized on the ulnar pedicle: A preliminary report and 1-year follow-up of two cases. Plast Reconstr Surg. 1992;89:1135-1147.
17. Mackinnon SE, Doolabh VB, Novak CB, Trulock EP. Clinical outcome following nerve allograft transplantation. Plast Reconstr Surg. 2001;107:1419-1429.
18. Strome M. Human laryngeal transplantation: Considerations and implications. Microsurgery 2000;20:372-374.
19. Strome M, Stein J, Esclamado R, et al. Laryngeal transplantation and 40-month follow-up. N Engl J Med. 2001;31:1676- 1679.
20. Jones TR, Humphrey PA, Brennan DC. Transplantation of vascularized allogeneic skeletal muscle for scalp reconstruction in a renal transplant patient. Transplant Proc. 1998;30:2746-2753.
21. Birchall M. Tongue transplantation. Lancet 2004;363:1663.
22. Rose KG, Sesterhenn K, Wustrow F. Tracheal allotransplantation in man. Lancet 1979;1:433.
23. Levashov Yu N, Yablonsky PK, Cherny SM, Orlov SV, Shafirovsky BB, Kuznetzov IM. One-stage allotransplantation of thoracic segment of the trachea in a patient with idiopathic fibrosing mediastinitis and marked tracheal stenosis. Eur JCardiothorac Surg. 1993;7:383-386.
24. Klepetko W, Marta GM, Wisser W, et al. Heterotopic tracheal transplantation with omentum wrapping in the abdominal position preserves functional and structural integrity of a human tracheal allograft. JThorac Cardiovasc Surg. 2004;127:862-867.
25. Buncke HJ, Hoffman WY, Alpert BS, Gordon L, Stefani AE. Microvascular transplant of two free scalp flaps between identical twins. Plast Reconstr Surg. 1982;70:605-609.
26. Jiang HQ, Wang Y, Hu XB, Li YS, Li JS. Composite tissue allograft transplantation of cephalocervical skin flap and two ears. Plast Reconstr Surg. 2005;115:31e-35e; discussion 36e-37e.
27. Hu W, Lu J, Zhang L, et al. A preliminary report of penile transplantation. Eur Urol. 2006;50:851-853.
28. Hu W, Lu J, Zhang L, et al. A preliminary report of penile transplantation: Part 2. Eur Urol. 2006;50:1115-1116; discussion 1116.
29. Dubernard JM. Penile transplantation? Eur Urol. 2006;50: 664-665.
30. Altman LK. French, in first, use a transplant to repair a face. The New York Times, December 1, 2005.
31. Butler PE, Clarke A, Hettiaratchy S. Facial transplantation. BMJ.2005;331:1349-1350.
32. The first facial transplant. Lancet 2005;366:1984.
33. Spurgeon B. Surgeons pleased with patient's progress after face transplant. BMJ. 2005;331:1359.
34. Devauchelle B, Badet L, Lengele B, et al. First human face allograft: Early report. Lancet 2006;368:203-209.
35. Dubernard JM, Lengele B, Morelon E, et al. Outcomes 18 months after the first human partial face transplantation. N Engl J Med. 2007;357:2451-2460.
36. Jesitus J. Chinese transplant surgery. Cosmetic Surgery Times 2006;9:12.
37. Man gets world's third partial face transplant. French doctors give 27-year-old with disfiguring disease a new nose, chin. Available at: http://www.msnbc.msn.com/id/16767785. Accessed June 16, 2008.
38. Siemionow M, Papay F, Alam D, et al. Near-total human face transplantation for a severely disfigured patient in the USA. Lancet 2009;374:203-209. Epub ahead of print July 14, 2009.
39. Siemionow M, Papay F, Djohan R, et al. First U.S. near-total human face transplantation: A paradigm shift for massive complex injuries. Plast Reconstr Surg. Epub ahead of print September 17, 2009.
40. Siemionow M, KulahciY. Experimental models of composite tissue allograft transplants. Semin Plast Surg. 2007;21:205.
41. Siemionow M, Kulahci Y. Experimental approaches to composite tissue allograft transplants. In: Lanzetta M, Dubernard JM, eds. Hand Transplantation. New York: Springer; 2007.
42. Siemionow M, Oke R, Ozer K, Izycki D, Prajapati R. Induction of donor-specific tolerance in rat hind-limb allografts under antilymphocyte serum and cyclosporine A protocol. J Hand Surg (Am.) 2002;27:1095-1103.
43. Ozer K, Gurunluoglu R, Zielinski M, Izycki D, Unsal M, Siemionow M. Extension of composite tissue allograft survival across major histocompatibility barrier under short course of anti-lymphocyte serum and cyclosporine a therapy. J Reconstr Microsurg. 2003;19:249-256.
44. Ozer K, Izycki D, Zielinski M, Siemionow M. Development of donor-specific chimerism and tolerance in composite tissue allografts under alphabeta-T-cell receptor monoclonal antibody and cyclosporine a treatment protocols. Microsurgery 2004;24:248-254.
45. Siemionow MZ, Izycki DM, Zielinski M. Donor-specific tolerance in fully major histocompatibility major histo- compatibility complex-mismatched limb allograft transplants under an anti-alphabeta T-cell receptor monoclonal antibody and cyclosporine A protocol. Transplantation 2003;76:1662-1668.
46. Ozer K, Oke R, Gurunluoglu R, et al. Induction of tolerance to hind limb allografts in rats receiving cyclosporine A and antilymphocyte serum: Effect of duration of the treatment. Transplantation 2003;75:31-36.
47. Siemionow M, Izycki D, Ozer K, Ozmen S, Klimczak A. Role of thymus in operational tolerance induction in limb allograft transplant model. Transplantation 2006;81:1568-1576.
48. Ozer K, Zielinski M, Siemionow M. New composite tissue allograft transplantation model in mouse with intravital microscopic evaluation ofmicrocirculation. J ReconstrMicrosurg. 2003;19:323-330.
49. Ozer K, Siemionow M. Combination of anti-ICAM-1 and anti-LFA-1 monoclonal antibody therapy prolongs allograft survival in rat hind-limb transplants. J Reconstr Microsurg. 2001;17:511-517; discussion 518.
50. Siemionow M, Ulusal BG, Ozmen S, Ulusal AE, Ozer K. Composite vascularized skin/bone graft model: A viable source for vascularized bone marrow transplantation. Microsurgery 2004;24:200-206.
51. Ozmen S, Ulusal BG, Ulusal AE, Izycki D, Siemionow M. Composite vascularized skin/bone transplantation models for bone marrow-based tolerance studies. Ann Plast Surg. 2006;56:295-300.
52. Siemionow MZ, Klimczak A, Unal S. Different routes ofdo- nor-derived hematopoietic stem cell transplantation for donor-specific chimerism induction across MHC barrier. Transplant Proc. 2005;37:62-64.
53. Siemionow M, Klimczak A, Unal S. Different routes of donor derived hematopoietic stem cells transplantation for donor specific chimerism induction across MHC barrier. Paper presented at: XX International Congress of the Transplantation Society; September 5-10, 2004; Vienna, Austria.
54. Siemionow M, Ozer K, Izycki D, Unsal M, Klimczak A. A new method of bone marrow transplantation leads to extension of skin allograft survival. Transplant Proc. 2005;37:2309-2314.
55. Demir Y, Ozmen S, Klimczak A, Mukherjee AL, Siemionow MZ. Strategies to develop chimerism in vascularized skin allografts across MHC barrier. Microsurgery 2005;25:415-422.
56. Agaoglu G, Siemionow M. Combined semimembranosus muscle and epigastric skin flap: A new model of composite- free flap in the rat. Ann Plast Surg. 2005;55:310-315.
57. Nasir S, Bozkurt M, Klimczak A, Siemionow M. Large anti- genic skin load in total abdominal wall transplants permits chimerism induction. Ann Plast Surg. 2008;161:572-579.
58. Agaoglu G, Unal S, Siemionow M. Transplantation of the vascularized bone allograft into the inguinal region. Plast Reconstr Surg. 2005;115:1794-1795. (Pubitemid 40604769)
59. Bozkurt M, Nasir S, Klimczak A, et al. The role ofthymus in chimerism induction on osseomusculocutaneous sternum, ribs, thymus pectoralis muscle skin allotransplantation model. Paper presented at: 24th Annual Meeting of the American Society of Reconstructive Microsurgery; January 14, 2008; Beverly Hills, Calif.
60. Siemionow M, Nasir S. Impact of donor bone marrow on survival of composite tissue allografts. Ann Plast Surg. 2008; 60:455-462.
61. Agaoglu G, Carnevale KA, Zins JE, Siemionow M. Bilateral vascularized femoral bone transplant: A new model of vas- cularized bone marrow transplantation in rats. Part I Ann Plast Surg. 2006;56:658-664.
62. Klimczak A, Agaoglu G, Carnevale KA, Siemionow M. Applications of bilateral vascularized femoral bone marrow transplantation for chimerism induction across the major histocompatibility (MHC) barrier: Part II. Ann Plast Surg. 2006;57:422-430.
63. Strome S, Sloman-Moll E, Samonte BR, Wu J, Strome M. Rat model for a vascularized laryngeal allograft. Ann Otol Rhinol Laryngol. 1992;101:950-953.
64. Lorenz RR, Dan O, Fritz MA, Nelson M, Strome M. Rat laryngeal transplant model: Technical advancements and a redefined rejection grading system. Ann Otol Rhinol Laryngol. 2002;111:1120-1127.
65. Akst LM, Siemionow M, Dan O, Izycki D, Strome M. Induction of tolerance in a rat model of laryngeal transplantation. Transplantation 2003;27:1763-1770.
66. Siemionow M, Kulahci Y. Facial transplantation. Semin Plast Surg. 2007;21:259.
67. Siemionow M, Kulahci Y. In preparation for facial transplantation. In: Eisenmann-Klein M, Neuhann-Lorens C, eds. Innovations in Plastic and Reconstructive Surgery. New York: Springer; 2008:146.
68. Siemionow M, Gozel-Ulusal B, Engin Ulusal A, Ozmen S, Izycki D, Zins JE. Functional tolerance following face transplantation in the rat. Transplantation 2003;15:1607-1609. (Pubitemid 36597309)
69. Ulusal BG, Ulusal AE, Ozmen S, Zins JE, Siemionow MZ. A new composite facial and scalp transplantation model in rats. Plast Reconstr Surg. 2003;112:1302-1311.
70. Unal S, Agaoglu G, Zins J, Siemionow M. New surgical approach in facial transplantation extends survival of allograft recipients. Ann Plast Surg. 2005;55:297-303.
71. Demir Y, Ozmen S, Klimczak A, Mukherjee AL, Siemionow M. Tolerance induction in composite facial allograft transplantation in the rat model. Plast Reconstr Surg. 2004;114: 1790-1801.
72. Yazici I, Unal S, Siemionow M. Composite hemiface/calvaria transplantation model in rats. Plast Reconstr Surg. 2006;118:1321-1327.
73. Kulahci Y, Klimczak A, Siemionow M. Long term survival of composite hemiface/mandible/tongue tissue allograft permitted by donor specific chimerism. Paper presented at: Plastic Surgery 2006, American Society of Plastic Surgeons Annual Meeting; October 6 -11, 2006; San Francisco, Calif.
74. Kulahci Y, Molski M, Siemionow M. Development of the alternative composite tissue allograft transplantation models for reconstruction of the head and neck defects. Paper presented at: 51st Annual Meeting of the Plastic Surgery Research Council; May 17-20, 2006; Dana Point, Calif.
75. Kulahci Y, Klimczak A, Siemionow M. Development and maintenance of donor specific chimerism in semi-allogenic major histocompatibility complex mismatched hemiface/ mandible/tongue flap under low dose cyclosporine a treatment. Paper presented at: Combined Meeting of the Ohio Valley and the Robert H. Ivy Societies of Plastic Surgeons; June 2-4, 2006; Pittsburgh, Pa.
76. Kulahci Y, Klimczak A, SiemionowM. Anewcomposite tissue allograft transplantation model for reconstruction of the head and neck defects and long term survival permitted by donor specific chimerism under low dose cyclosporine A treatment. Paper presented at: 23rd Annual Meeting of the American Society of Reconstructive Microsurgery; January 13-16, 2007; Rio Grande, Puerto Rico.
77. Bozkurt M, Kulahci Y, Nasir S, Klimczak A, Siemionow M. Long-term survival of composite hemiface/mandible/ tongue tissue allograft permitted by donor specific chimerism. Paper presented at: 52nd Annual Meeting ofthe Plastic Surgery Research Council; June 20-23, 2007; Stanford, Calif.
78. Kulahci Y, Siemionow M. A new composite hemiface/man- dible/tongue transplantation model in rats. Ann Plast Surg. (in press).
79. Yazici I, Carnevale K, Klimczak A, Siemionow M. A new rat model of maxilla allotransplantation. Ann Plast Surg. 2007;58:338-344.
80. Bozkurt M, Nasir S, Klimczak A, et al. Composite osseomusculo- cutaneous hemiface/nose, lower lip and premaxilla allograft transplant. Paper presented at: 52nd Annual Meeting of the Plastic Surgery Research Council; June 20 -23, 2007; Stanford, Calif.
81. Bozkurt M, Sonmez E, Grykien C, et al. Evaluation of function of composite osseomusculocutaneous nose, lower lip and premaxilla allograft transplants via somatosensory evoked potentials. Paper presented at: 17th Annual Meeting of the American Society for Peripheral Nerve; January 13,2008; Beverly Hills, Calif.
82. Zor F, Bozkurt M, Dileep N, Siemionow M. A new composite midface allotransplantation model with sensory and motor reinnervation. Transpl Int. (in press).
83. Sonmez E, Nasir S, Siemionow M. Penile allotransplantation model in rat. Ann Plast Surg. 2009;62:304-310.
84. Imhof M, Bergmeister H, Lipovac M, Rudas M, Hofstetter G, Huber J. Orthotopic microvascular reanastomosis of whole cryopreserved ovine ovaries resulting in pregnancy and live birth. Fertil Steril. 2006;85(Suppl):1208-1215.
85. Jeremias E, Bedaiwy MA, Gurunluoglu R, Biscoti CV, Siemi- onow M, Falcone T. Heterotopic autotransplantation of the ovary with microvascular anastomosis: A novel surgical technique. Fertil Steril. 2002;77:1278-1282.