Strategies to develop chimerism in vascularized skin allografts across MHC barrier

Microsurgery

Volumn 25, Issue 5, 2005, Pages 415-422

  Demir, Yavuz ^a   Ozmen, Selahattin ^a   Klimczak, Aleksandra ^a   Mukherjee, Abir Lal ^a   Siemionow, Maria Z ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY T LYMPHOCYTE RECEPTOR ALPHA BETA CHAIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TACROLIMUS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIMERA; CLINICAL PROTOCOL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; EXPERIMENTAL MODEL; FLOW CYTOMETRY; GRAFT REJECTION; GRAFT SURVIVAL; HISTOPATHOLOGY; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; MAJOR HISTOCOMPATIBILITY COMPLEX; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SKIN ALLOGRAFT; SKIN BIOPSY; SURVIVAL RATE; TECHNIQUE;

ANTIBODIES, MONOCLONAL; CHIMERISM; CYCLOSPORINE; GRAFT SURVIVAL; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; MAJOR HISTOCOMPATIBILITY COMPLEX; RATS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SKIN TRANSPLANTATION; SURGICAL FLAPS; TACROLIMUS; TRANSPLANTATION, HOMOLOGOUS;

EID: 23244465194     PISSN: 07381085     EISSN: None     Source Type: Journal    
DOI: 10.1002/micr.20140     Document Type: Article

References (36)

1. Lee WP, Yaremchuk MJ, Pan YC, Randolph MA, Tan CM, Weiland AJ. Relative antigenicity of components of vascularized limb allografts. Plast Reconstr Surg 1991;87:401-411.
2. Siemionow M, Ozer K. Advances in composite tissue allograft transplantation related to the hand and upper extremity. J Hand Surg [Am] 2002;27:565-580.
3. Hewitt CW, Black KS, Fraser LA, Howard EB, Martin DC, Achauer BM, Furnas DW. Composite tissue (limb) allografts in rats. I. Dose-dependent increase in survival with cyclosporine. Transplantation 1985;39:360-364.
4. Black KS, Hewitt CW, Fraser LA, Howard EB, Martin DC, Achauer BM, Furnas DW. Composite tissue (limb) allografts in rats. II. Indefinite survival using low-dose cyclosporine. Transplantation 1985;39:365-368.
5. Cendales L, Hardy MA. Immunologic considerations in composite tissue transplantation: overview. Microsurgery 2000;20:412-419.
6. Gorantla VS, Barker JH, Jones JW Jr, Prabhune K, Maldonado C, Granger DK. Immunosuppressive agents in transplantation: mechanism of action and current anti-rejection strategies. Microsurgery 2000;20:420-429.
7. Nomoto K, Yung-Yun K, Omoto K, Umesue M, Murakami Y, Matsuzaki G, Nomoto K. Tolerance induction in a fully allogeneic combination using anti-T cell receptor-αβ monoclonal antibody, low dose irradiation, and donor bone marrow transfusion. Transplantation 1985;59:395-401.
8. Hale DA, Gottschalk R, Umemura A, Maki T, Monaco AP. Immunologic mechanisms in tolerance produced in mice with nonradiation-based lymphoablation and donor-specific bone marrow. Transplantation 2002;74:477-484.
9. Manilay OJ, Pearson DA, Sergio JJ, Swenson KG, Sykes M. Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning regimen. Transplantation 1998;66:96-102.
10. Fuchimoto Y, Huang CA, Yamada K, Shimizu A, Kitamura H, Colvin RB, Ferrara V, Murphy MC, Sykes M, White-Scharf M, Neville DM Jr, Sachs DH. Mixed chimerism and tolerance without whole body irradiation in a large animal model. J Clin Invest 2000;105:1779-1789.
11. de Vries-van der Zwan A, Besseling AC, de Waal LP, Boog CJ. Specific tolerance induction and transplantation. A single-day protocol. Blood 1997;89:2596-2601.
12. Blaha P, Bigenzahn S, Koporc Z, Schmid M, Langer F, Selzer E, Bergmeister H, Wrba F, Kurtz J, Kiss C, Roth E, Muehlbacher F, Sykes M, Wekerle T. The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with co-stimulation blockage. Blood 2003;101:2886-2893.
13. Siemionow M, Ortak T, Izycki D, Oke R, Cunningham B, Prajapati R, Zins JE. Induction of tolerance in composite tissue allografts. Transplantation 2002;74:1211-1217.
14. Cober SR, Randolph MA, Lee WP. Skin allograft survival following intrathymic injection of donor bone marrow. J Surg Res 1999;85:204-208.
15. Schorlemmer HU, Bartlett RR, Lindner JK, Kurrle R. Coadministration of malononitrilamides and tacrolimus induces tolerance in a rat skin allograft model. Transplant Proc 1999;31:1184-1188.
16. Bartlett AS, McCall JL, Ameratunga R, Yeong ML, Benjamin CD, Peach R, Munn SR. Prolongation of fully allogeneic skin graft survival in the rat by combined administration of costimulatory blockade and sirolimus. Transplant Proc 2002;34:1127-1129.
17. Buttemeyer R, Jones NF, Min Z, Rao U. Rejection of the component tissues of limb allograft in rats immunosuppressed with FK-506 and cyclosporine. Plast Reconstr Surg 1996;97:139-148.
18. Ozer K, Oke R, Gurunluoglu R, Zielinski M, Izycki D, Prajapati R, Siemionow M. Induction of tolerance to hind limb allografts in rats receiving cyclosporine A and antilymphocyte serum: the effect of duration of the treatment. Transplantation 2003;75:31-36.
19. Siemionow M, Oke R, Ozer K, Izycki D, Prajapati R. Induction of donor-specific tolerance under antilymphocyte serum and cyclosporine A protocol. J Hand Surg [Am] 2002;27:1095-1103.
20. Stingl G, Gazze-Stingl LA, Aberer W, Wolff K. Antigen presentation by murine epidermal Langerhans' cells and its alteration by ultraviolet B light. J Immunol 1981;127:1707-1713.
21. Francois CG, Breidenbach WC, Maldonado C, Maldonado C, Kakoulidis TP, Hodges A, Dubernard JM, Owen E, Pei G, Ren X, Barker JH. Hand transplantation: comparisons and observations of the first clinical cases. Microsurgery 2000;20:360-371.
22. Fuchimoto Y, Gleit ZL, Huang CA, Kitamura H, Schwarze ML, Menard MT, Mawulawde K, Madsen JC, Sachs DH. Skin-specific alloantigens in miniature swine. Transplantation 2001;72:122-126.
23. Mathes DW, Randolph MA, Solari MG, Nazzal JA, Nielsen GP, Arn JS, Sachs DH, Lee WP. Split tolerance to a composite tissue allograft in a swine model. Transplantation 2003;75:25-31.
24. Ildstad ST, Sachs DH. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature 1984;307:168-170.
25. Ishii E, Gengozian N, Good RA. Influence of dimethyl myleran on tolerance induction and immune function in major histocompatibility complex- haploidentical murine bone-marrow transplantation. Proc Natl Acad Sci USA 1991;88:8435-8439.
26. Steinmuller D. The enigma of skin allograft rejection. Transplant Rev 1998;12:42-57.
27. Cho SI, Marcus FS, Kountz SL. A new model for study of allograft rejection in the rat: use of skin with an intact vascular pedicle. I. Transplantation 1972;13:486-492.
28. Salver KE, Kyger ER III. Studies in rats of survival of composite homotransplants of skin and subcutaneous tissue, with microvascular anastomoses. Plast Reconstr Surg 1973;51:672-681.
29. Wustrack KO, Gruber RP, Lucas ZJ. Immunological enhancement of skin allografts in the rat. Role of vascular and lymphatic reconstitution. Transplantation 1975;19:156-165.
30. Kim SK, Aziz S, Oyer P, Hentz VR. Use of cyclosporine A in allotransplantation of rat limbs. Ann Plast Surg 1984;12:249-255.
31. Benhaim P, Anthony JP, Ferreira L, Borsanyi JP, Mathes SJ. Use of combination of low-dose cyclosporine and RS-61443 in a rat hindlimb model of composite tissue allotransplantation. Transplantation 1996;61:527-532.
32. Murakami Y, Kong YY, Nishimura Y, Nomoto K, Umesue M, Omoto K, Maeda T, Nomoto K. Prevention of anti-T-cell receptor alpha beta monoclonal antibody-induced side-effects by treatment with cyclosporin A without interference of monoclonal antibody-induced immunosuppression in mice. Immunology 1995;86:238-243.
33. Heidecke CD, Hancock WW, Westerholt S, Sewczik T, Jakobs F, Zantl N, Varzaru A, Siegling A, Kurrle R, Deusch K, Volk HD, Kupiec-Weglinski JW. Alpha/beta-T cell receptor-directed therapy in rat allograft recipients. Long-term survival of cardiac allografts after pretreatment with R73 mAb is associated with upregulation of Th2-type cytokines. Transplantation 1996; 61:948-956.
34. Knechtle SJ, Vargo D, Fechner J, Zhai Y, Wang J, Hanaway MJ, Scharff TJ, Hu H, Knapp L, Watkins D, Neville DM Jr. FN18-CRM9 immunotoxin promotes tolerance in primate renal allografts. Transplantation 1997;63:1-6.
35. Hale DA, Gottschalk R, Umemura A, Maki T, Monaco AP. Establishment of stable multilineage hematopoietic chimerism and donor-specific tolerance without irradiation. Transplantation 2000;69:1242-1251.
36. Siemionow MZ, Izycki DM, Zielinski M. Donor-specific tolerance in fully major histocompatibility complex-mismatched limb allograft transplants under an anti-αβ T-cell receptor monoclonal antibody and cyclosporine A protocol. Transplantation 2003; 76:1662-1668.