Role of AKT kinase in measles virus replication

Journal of Virology

Volumn 84, Issue 4, 2010, Pages 2180-2183

  Carsillo, Mary ^a   Kim, Dhohyung ^a   Niewiesk, Stefan ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOGEN SYNTHASE KINASE 3; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; COTTON RAT; DOWN REGULATION; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; MEASLES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPLEEN CELL; VIRUS INFECTION; VIRUS RECOMBINANT; VIRUS REPLICATION;

ANIMALS; CERCOPITHECUS AETHIOPS; HOST-PATHOGEN INTERACTIONS; HUMANS; JURKAT CELLS; MEASLES; MEASLES VIRUS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; SIGMODONTINAE; SPLEEN; TRANSFECTION; VERO CELLS; VIRUS REPLICATION;

DNA VIRUSES; MEASLES VIRUS; SIGMODON;

EID: 75449116989     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01316-09     Document Type: Article

References (18)

1. Avota, E., A. Avots, S. Niewiesk, L. P. Kane, U. Bommhardt, and V. S.-S. S. ter Meulen. 2001. Disruption of Akt kinase activation is important for immunosuppression induced by measles virus. Nat. Med. 7:725-731.
2. Buchkovich, N. J., Y. Yu, C. A. Zampieri, and J. C. Alwine. 2008. The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway. Nat. Rev. Microbiol. 6:266-275.
3. Cooray, S. 2004. The pivotal role of phosphatidylinositol 3-kinase-Akt signal transduction in virus survival. J. Gen. Virol. 85:1065-1076.
4. Ehrhardt, C., and S. Ludwig. 2009. A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway. Cell Microbiol. 11:863-871.
5. Ganesan, L. P., G. Wei, R. A. Pengal, L. Moldovan, N. Moldovan, M. C. Ostrowski, and S. Tridandapani. 2004. The serine/threonine kinase Akt promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase. J. Biol. Chem. 279:54416-54425.
6. Ji, W. T., and H. J. Liu. 2008. PI3K-Akt signaling and viral infection. Recent Pat. Biotechnol. 2:218-226.
7. Kane, L. P., V. S. Shapiro, D. Stokoe, and A. Weiss. 1999. Induction of NF-kappaB by the Akt/PKB kinase. Curr. Biol. 9:601-604.
8. Naniche, D., G. Varior-Krishnan, G. Cervoni, T. F. Wild, B. Rossi, C. Rabourdin-Combe, and D. Gerlier. 1993. Human membrane cofactor protein (CD46) acts as cellular receptor for measles virus. J. Virol. 67:6025-6032.
9. Niewiesk, S., I. Eisenhuth, A. Fooks, J. C. S. Clegg, J.-J. Schnorr, S. Schneider-Schaulies, and V. ter Meulen. 1997. Measles virus-induced immune suppression in the cotton rat (Sigmodon hispidus) model depends on viral glycoproteins. J. Virol. 71:7214-7219.
10. Niewiesk, S., M. Götzelmann, and V. ter Meulen. 2000. Selective in vivo suppression of T lymphocyte responses in experimental measles virus infection. Proc. Natl. Acad. Sci. U. S. A. 74:4652-4657.
11. Onishi, K., M. Higuchi, T. Asakura, N. Masuyama, and Y. Gotoh. 2007. The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts. Genes Cells 12:535-546.
12. Plumet, S., and D. Gerlier. 2005. Optimized SYBR green real-time PCR assay to quantify the absolute copy number of measles virus RNAs using gene specific primers. J. Virol. Methods 128:79-87.
13. Qian, Y., L. Corum, Q. Meng, J. Blenis, J. Z. Zheng, X. Shi, D. C. Flynn, and B. H. Jiang. 2004. PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration. Am. J. Physiol. Cell Physiol. 286:C153-C163.
14. Radecke, F., P. Spielhofer, H. Schneider, K. Kaelin, M. Huber, C. Dötsch, G. Christiansen, and M. A. Billeter. 1995. Rescue of measles virus from cloned DNA. EMBO J. 14:5773-5784.
15. Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty per cent endpoints. Am. J. Hygiene 27:493-497.
16. Schlender, J., J. J. Schnorr, T. Cattomen, R. Cattaneo, M. A. Billeter, V. Ter Meulen, and S. Schneider-Schaulies. 1996. Surface interaction of measles virus glycoproteins is necessary and sufficient for the induction of proliferative inhibition of human peripheral blood mononuclear cells. Proc. Natl. Acad. Sci. U. S. A. 93:13194-13199.
17. Sun, M., S. M. Fuentes, K. Timani, D. Sun, C. Murphy, Y. Lin, A. August, M. N. Teng, and B. He. 2008. Akt plays a critical role in replication of nonsegmented negative-stranded RNA viruses. J. Virol. 82:105-114.
18. Zhan, X., J. L. Hurwitz, S. Krishnamurthy, T. Takimoto, K. Boyd, R. A. Scroggs, S. Surman, A. Portner, and K. S. Slobod. 2007. Respiratory syncytial virus (RSV) fusion protein expressed by recombinant Sendai virus elicits B-cell and T-cell responses in cotton rats and confers protection against RSV subtypes A and B. Vaccine 25:8782-8793.