메뉴 건너뛰기




Volumn 21, Issue 1, 2010, Pages 53-59

Ginkgo biloba extract EGb761 protects against mitochondrial dysfunction in platelets and hippocampi in ovariectomized rats

Author keywords

Ginkgo; Mitochondrial dysfunction; Neurodegeneration; Ovariectomy; Platelet

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C OXIDASE; ESTROGEN; GINKGO BILOBA EXTRACT; GLUTATHIONE;

EID: 75449115920     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537100903395180     Document Type: Article
Times cited : (20)

References (43)
  • 1
    • 0034237719 scopus 로고    scopus 로고
    • Energetics in the pathogenesis of neurodegenerative diseases
    • Beal MF. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci 2000;23:298-304.
    • (2000) Trends Neurosci , vol.23 , pp. 298-304
    • Beal, M.F.1
  • 2
    • 0028053251 scopus 로고
    • Cognitive deficits of men and women with Alzheimer disease
    • Henderson VW, Buckwalter JG. Cognitive deficits of men and women with Alzheimer disease. Neurology 1994;44:90-96.
    • (1994) Neurology , vol.44 , pp. 90-96
    • Henderson, V.W.1    Buckwalter, J.G.2
  • 3
    • 0017810263 scopus 로고
    • Do mitochondria produce oxygen radicals in vivo?
    • Nohl H, Hegner D. Do mitochondria produce oxygen radicals in vivo? Eur J Biochem 1978;82:563-567.
    • (1978) Eur J Biochem , vol.82 , pp. 563-567
    • Nohl, H.1    Hegner, D.2
  • 4
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979;59:527-605.
    • (1979) Physiol Rev , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 6
    • 50649125445 scopus 로고    scopus 로고
    • Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid
    • García-Ayllón MS, Silveyra MX, Sáez-Valero J. Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid. Chem Biol Interact 2008; 175:209-215.
    • (2008) Chem Biol Interact , vol.175 , pp. 209-215
    • García-Ayllón, M.S.1    Silveyra, M.X.2    Sáez-Valero, J.3
  • 7
    • 50949100957 scopus 로고    scopus 로고
    • Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
    • Dinamarca MC, Arrázola M, Toledo E, Cerpa WF, Hancke J, Inestrosa NC. Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. Chem Biol Interact 2008;175:142-149.
    • (2008) Chem Biol Interact , vol.175 , pp. 142-149
    • Dinamarca, M.C.1    Arrázola, M.2    Toledo, E.3    Cerpa, W.F.4    Hancke, J.5    Inestrosa, N.C.6
  • 8
    • 0037373449 scopus 로고    scopus 로고
    • Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males
    • Borrás C, Sastre J, García-Sala D, Lloret A, Pallardó FV, Viña J. Mitochondria from females exhibit higher antioxidant gene expression and lower oxidative damage than males. Free Radic Biol Med 2003;34:546-552.
    • (2003) Free Radic Biol Med , vol.34 , pp. 546-552
    • Borrás, C.1    Sastre, J.2    García-Sala, D.3    Lloret, A.4    Pallardó, F.V.5    Viña, J.6
  • 9
    • 34249665677 scopus 로고    scopus 로고
    • Mitochondrial oxidant generation is involved in determining why females live longer than males
    • Borras C, Gambini J, Vina J. Mitochondrial oxidant generation is involved in determining why females live longer than males. Front Biosci 2007;12:1008-1013.
    • (2007) Front Biosci , vol.12 , pp. 1008-1013
    • Borras, C.1    Gambini, J.2    Vina, J.3
  • 11
    • 52949124068 scopus 로고    scopus 로고
    • Effects of phytoestrogen on mitochondrial structure and function of hippocampal CA1 region of ovariectomized rats
    • Xu XW, Shi C, He ZQ, Ma CM, Chen WH, Shen YP, Guo Q, Shen CJ, Xu J. Effects of phytoestrogen on mitochondrial structure and function of hippocampal CA1 region of ovariectomized rats. Cell Mol Neurobiol 2008;28:875-886.
    • (2008) Cell Mol Neurobiol , vol.28 , pp. 875-886
    • Xu, X.W.1    Shi, C.2    He, Z.Q.3    Ma, C.M.4    Chen, W.H.5    Shen, Y.P.6    Guo, Q.7    Shen, C.J.8    Xu, J.9
  • 12
    • 40649107161 scopus 로고    scopus 로고
    • Possible role of mitochondrial dysfunction in central neurodegeneration of ovariectomized rats
    • Shi C, Xu XW, Forster EL, Tang LF, Ge Z, Yew DT, Xu J. Possible role of mitochondrial dysfunction in central neurodegeneration of ovariectomized rats. Cell Biochem Funct 2008;26:172-178.
    • (2008) Cell Biochem Funct , vol.26 , pp. 172-178
    • Shi, C.1    Xu, X.W.2    Forster, E.L.3    Tang, L.F.4    Ge, Z.5    Yew, D.T.6    Xu, J.7
  • 13
    • 60849096071 scopus 로고    scopus 로고
    • Increased vulnerability of brain to estrogen withdrawal-induced mitochondrial dysfunction with aging
    • Shi C, Xu J. Increased vulnerability of brain to estrogen withdrawal-induced mitochondrial dysfunction with aging. J Bioenerg Biomembr 2008;40:625-630.
    • (2008) J Bioenerg Biomembr , vol.40 , pp. 625-630
    • Shi, C.1    Xu, J.2
  • 14
    • 0030759072 scopus 로고    scopus 로고
    • A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia
    • North American EGb Study Group
    • Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AF. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA 1997;278: 1327-1332.
    • (1997) JAMA , vol.278 , pp. 1327-1332
    • Le Bars, P.L.1    Katz, M.M.2    Berman, N.3    Itil, T.M.4    Freedman, A.M.5    Schatzberg, A.F.6
  • 15
    • 28244446721 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type
    • Schneider LS, Dekosky ST, Farlow MR, Tariot PN, Hoerr R, Kieser M. A randomized, double-blind, placebo-controlled trial of two doses of Ginkgo biloba extract in dementia of the Alzheimer's type. Curr Alzheimer Res 2005;2:541-551.
    • (2005) Curr Alzheimer Res , vol.2 , pp. 541-551
    • Schneider, L.S.1    Dekosky, S.T.2    Farlow, M.R.3    Tariot, P.N.4    Hoerr, R.5    Kieser, M.6
  • 16
    • 33846820304 scopus 로고    scopus 로고
    • Ginkgo biloba special extract in dementia with neuropsychiatric features: A randomised, placebo-controlled, double-blind clinical trial
    • Napryeyenko O, Borzenko I. Ginkgo biloba special extract in dementia with neuropsychiatric features. A randomised, placebo-controlled, double-blind clinical trial. Arzneimittelforschung 2007;57:4-11. (Pubitemid 46212982)
    • (2007) Arzneimittel-Forschung/Drug Research , vol.57 , Issue.1 , pp. 4-11
    • Napryeyenko, O.1    Borzenko, I.2
  • 17
    • 0034125340 scopus 로고    scopus 로고
    • A 26-week analysis of a double-blind, placebo-controlled trial of the Ginkgo biloba extract EGb 761 in dementia
    • Le Bars PL, Kieser M, Itil KZ. A 26-week analysis of a double-blind, placebo-controlled trial of the Ginkgo biloba extract EGb 761 in dementia. Dement Geriatr Cogn Disord 2000;11:230-237.
    • (2000) Dement Geriatr Cogn Disord , vol.11 , pp. 230-237
    • Le Bars, P.L.1    Kieser, M.2    Itil, K.Z.3
  • 18
    • 0029871249 scopus 로고    scopus 로고
    • Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia
    • Kanowski S, Herrmann WM, Stephan K, WierichW, Horr R. Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry 1996;29:47-56.
    • (1996) Pharmacopsychiatry , vol.29 , pp. 47-56
    • Kanowski, S.1    Herrmann, W.M.2    Stephan, K.3    Wierich, W.4    Horr, R.5
  • 20
    • 0037151567 scopus 로고    scopus 로고
    • Ginkgo for memory enhancement: A randomized controlled trial
    • Solomon PR, Adams F, Silver A, Zimmer J, DeVeaux R. Ginkgo for memory enhancement: a randomized controlled trial. JAMA 2002;288:835-840.
    • (2002) JAMA , vol.288 , pp. 835-840
    • Solomon, P.R.1    Adams, F.2    Silver, A.3    Zimmer, J.4    Deveaux, R.5
  • 21
    • 0033844767 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced oxidative damage and apoptosis in cerebellar granule cells: Protection by Ginkgo biloba extract
    • Wei T, Ni Y, Hou J, Chen C, Zhao B, Xin W. Hydrogen peroxide-induced oxidative damage and apoptosis in cerebellar granule cells: protection by Ginkgo biloba extract. Pharmacol Res 2000;41:427-433.
    • (2000) Pharmacol Res , vol.41 , pp. 427-433
    • Wei, T.1    Ni, Y.2    Hou, J.3    Chen, C.4    Zhao, B.5    Xin, W.6
  • 22
    • 33845613251 scopus 로고    scopus 로고
    • Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
    • Wu Y, Wu Z, Butko P, Christen Y, Lambert MP, Klein WL, Link CD, Luo Y. Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J Neurosci 2006;26:13102-13113.
    • (2006) J Neurosci , vol.26 , pp. 13102-13113
    • Wu, Y.1    Wu, Z.2    Butko, P.3    Christen, Y.4    Lambert, M.P.5    Klein, W.L.6    Link, C.D.7    Luo, Y.8
  • 23
    • 0033580036 scopus 로고    scopus 로고
    • Ginkgo biloba extract (EGb 761) protects Na,K-ATPase activity during cerebral ischemia in mice
    • Pierre S, Jamme I, Droy-Lefaix M, Nouvelot A, Maixent J. Ginkgo biloba extract (EGb 761) protects Na,K-ATPase activity during cerebral ischemia in mice. Neuroreport 1999;10:47-51.
    • (1999) Neuroreport , vol.10 , pp. 47-51
    • Pierre, S.1    Jamme, I.2    Droy-Lefaix, M.3    Nouvelot, A.4    Maixent, J.5
  • 24
    • 0031002231 scopus 로고    scopus 로고
    • Ginkgo biloba extract (EGb 761) pretreatment limits free radicalinduced oxidative stress in patients undergoing coronary bypass surgery
    • Pietri S, Seguin J, d'Arbigny P, Drieu K, Culcasi M. Ginkgo biloba extract (EGb 761) pretreatment limits free radicalinduced oxidative stress in patients undergoing coronary bypass surgery. Cardiovasc Drugs Ther 1997;11:121-131.
    • (1997) Cardiovasc Drugs Ther , vol.11 , pp. 121-131
    • Pietri, S.1    Seguin, J.2    D'Arbigny, P.3    Drieu, K.4    Culcasi, M.5
  • 26
    • 0032427502 scopus 로고    scopus 로고
    • Effects of ginkgolides on interleukin-1, tumor necrosis factor-alpha and nitric oxide production by rat microglia stimulated with lipolpolysaccharides in vitro
    • Du ZY, Li XY. Effects of ginkgolides on interleukin-1, tumor necrosis factor-alpha and nitric oxide production by rat microglia stimulated with lipolpolysaccharides in vitro. Arzneimittelforschung 1998;48:1126-1130.
    • (1998) Arzneimittelforschung , vol.48 , pp. 1126-1130
    • Du, Z.Y.1    Li, X.Y.2
  • 27
    • 0141749421 scopus 로고    scopus 로고
    • Neuroprotective effects of Ginkgo biloba extract
    • Ahlemeyer B, Krieglstein J. Neuroprotective effects of Ginkgo biloba extract. Cell Mol Life Sci 2003;60:1779-1792.
    • (2003) Cell Mol Life Sci , vol.60 , pp. 1779-1792
    • Ahlemeyer, B.1    Krieglstein, J.2
  • 28
    • 0036203108 scopus 로고    scopus 로고
    • Ginkgo biloba extracts (EGb 761) and bilobalide increase NADH dehydrogenase mRNA level and mitochondrial respiratory control ratio in PC12 cells
    • Tendi EA, Bosetti F, Dasgupta SF, Stella AM, Drieu K, Rapoport SI. Ginkgo biloba extracts (EGb 761) and bilobalide increase NADH dehydrogenase mRNA level and mitochondrial respiratory control ratio in PC12 cells. Neurochem Res 2002;27:319-323.
    • (2002) Neurochem Res , vol.27 , pp. 319-323
    • Tendi, E.A.1    Bosetti, F.2    Dasgupta, S.F.3    Stella, A.M.4    Drieu, K.5    Rapoport, S.I.6
  • 29
    • 0842324683 scopus 로고    scopus 로고
    • Increased transcription of mitochondrial genes for complex i in human platelets during ageing
    • Merlo Pich M, Raule N, Catani L, Fagioli ME, Faenza I, Cocco L, Lenaz G. Increased transcription of mitochondrial genes for complex I in human platelets during ageing. FEBS Lett 2004;558:19-22.
    • (2004) FEBS Lett , vol.558 , pp. 19-22
    • Merlo Pich, M.1    Raule, N.2    Catani, L.3    Fagioli, M.E.4    Faenza, I.5    Cocco, L.6    Lenaz, G.7
  • 31
    • 0032490091 scopus 로고    scopus 로고
    • Human complex i defects in neurodegenerative diseases
    • Schapira AH. Human complex I defects in neurodegenerative diseases. Biochim Biophys Acta 1998;1364:261-270.
    • (1998) Biochim Biophys Acta , vol.1364 , pp. 261-270
    • Schapira, A.H.1
  • 32
    • 34249909201 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in platelets and hippocampi of senescenceaccelerated mice
    • Xu J, Shi C, Li Q, Wu J, Forster EL, Yew DT. Mitochondrial dysfunction in platelets and hippocampi of senescenceaccelerated mice. J Bioenerg Biomembr 2007;39:195-202.
    • (2007) J Bioenerg Biomembr , vol.39 , pp. 195-202
    • Xu, J.1    Shi, C.2    Li, Q.3    Wu, J.4    Forster, E.L.5    Yew, D.T.6
  • 33
    • 34548356758 scopus 로고    scopus 로고
    • Effects of beta-amyloid peptide and estrogen on platelet mitochondrial function of Sprague-Dawley rats
    • Xu J, Shi C, Li Q, Lam WP, Wai MS, Yew DT. Effects of beta-amyloid peptide and estrogen on platelet mitochondrial function of Sprague-Dawley rats. Platelets 2007;18:460-468.
    • (2007) Platelets , vol.18 , pp. 460-468
    • Xu, J.1    Shi, C.2    Li, Q.3    Lam, W.P.4    Wai, M.S.5    Yew, D.T.6
  • 34
    • 43649092320 scopus 로고    scopus 로고
    • Effects of ageing and Alzheimer's disease on mitochondrial function of human platelets
    • Shi C, Guo K, Yew DT, Yao Z, Forster EL, Wang H, Xu J. Effects of ageing and Alzheimer's disease on mitochondrial function of human platelets. Exp Gerontol 2008;43:589-594.
    • (2008) Exp Gerontol , vol.43 , pp. 589-594
    • Shi, C.1    Guo, K.2    Yew, D.T.3    Yao, Z.4    Forster, E.L.5    Wang, H.6    Xu, J.7
  • 36
    • 34248373221 scopus 로고    scopus 로고
    • Effects of genistein on hippocampal neurodegeneration of ovariectomized rats
    • Xu J, Zhu J, Shi C, Guo K, Yew DT. Effects of genistein on hippocampal neurodegeneration of ovariectomized rats. J Mol Neurosci 2007;31:101-112.
    • (2007) J Mol Neurosci , vol.31 , pp. 101-112
    • Xu, J.1    Zhu, J.2    Shi, C.3    Guo, K.4    Yew, D.T.5
  • 37
    • 0043166643 scopus 로고    scopus 로고
    • Decreased platelet cytochrome c oxidase activity is accompanied by increased blood lactate concentration during exercise in patients with Alzheimer disease
    • Mancuso M, Filosto M, Bosetti F, Ceravolo R, Rocchi A, Tognoni G, Manca ML, Solaini G, Siciliano G, Murri L. Decreased platelet cytochrome c oxidase activity is accompanied by increased blood lactate concentration during exercise in patients with Alzheimer disease. Exp Neurol 2003;182:421-426.
    • (2003) Exp Neurol , vol.182 , pp. 421-426
    • Mancuso, M.1    Filosto, M.2    Bosetti, F.3    Ceravolo, R.4    Rocchi, A.5    Tognoni, G.6    Manca, M.L.7    Solaini, G.8    Siciliano, G.9    Murri, L.10
  • 38
    • 0035036467 scopus 로고    scopus 로고
    • The mitochondrial theory of aging
    • Kowald A. The mitochondrial theory of aging. Biol Signals Recept 2001;10:162-175.
    • (2001) Biol Signals Recept , vol.10 , pp. 162-175
    • Kowald, A.1
  • 39
    • 0029871249 scopus 로고    scopus 로고
    • Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia
    • Kanowski S, Herrmann WM, Stephan K, Wierich W, Hörr R. Proof of efficacy of the ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry 1996;29:47-56.
    • (1996) Pharmacopsychiatry , vol.29 , pp. 47-56
    • Kanowski, S.1    Herrmann, W.M.2    Stephan, K.3    Wierich, W.4    Hörr, R.5
  • 42
    • 75349107818 scopus 로고    scopus 로고
    • The effect of ovariectomy and estrogen on penetrating brain arterioles and blood-brain barrier permeability
    • Cipolla MJ, Godfrey JA, Wiegman MJ. The effect of ovariectomy and estrogen on penetrating brain arterioles and blood-brain barrier permeability. Microcirculation 2009;9:1-10.
    • (2009) Microcirculation , vol.9 , pp. 1-10
    • Cipolla, M.J.1    Godfrey, J.A.2    Wiegman, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.