Impact of preoperative anemia on cardiac surgery in octogenarians

Interactive Cardiovascular and Thoracic Surgery

Volumn 10, Issue 2, 2010, Pages 249-255

  Carrascal, Yolanda ^a   Maroto, Laura ^a   Rey, Juvenal ^a   Arévalo, Adolfo ^a   Arroyo, Jaime ^a   Echevarría, José R ^a   Arce, Nuria ^a   Fulquet, Enrique ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

Author keywords

Anemia; Cardiac surgery; Octogenarians

Indexed keywords

ACUTE HEART INFARCTION; AGED; ANEMIA; CARDIOPULMONARY BYPASS; CEREBROVASCULAR ACCIDENT; CONFERENCE PAPER; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY BYPASS SURGERY; ELECTIVE SURGERY; ERYTHROCYTE TRANSFUSION; FEMALE; FORWARD HEART FAILURE; HEART ATRIUM FIBRILLATION; HEART SURGERY; HEART VALVE REPLACEMENT; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTESTINE ISCHEMIA; KIDNEY FAILURE; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIPLE ORGAN FAILURE; NEUROLOGICAL COMPLICATION; OUTPATIENT CARE; OVERALL SURVIVAL; PERIOPERATIVE COMPLICATION; POSTOPERATIVE COMPLICATION; PREOPERATIVE COMPLICATION; PRIORITY JOURNAL; RESPIRATORY FAILURE; SEPSIS; SURGICAL INFECTION; SURGICAL MORTALITY;

AGE FACTORS; AGED, 80 AND OVER; ANEMIA; BLOOD VESSEL PROSTHESIS IMPLANTATION; CORONARY ARTERY BYPASS; CREATININE; ERYTHROCYTE TRANSFUSION; FEMALE; HEMATOCRIT; HEMOGLOBINS; HOSPITAL MORTALITY; HUMANS; KAPLAN-MEIERS ESTIMATE; LENGTH OF STAY; LOGISTIC MODELS; MALE; ODDS RATIO; PERIPHERAL VASCULAR DISEASES; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; RISK FACTORS; SURGICAL PROCEDURES, ELECTIVE; TIME FACTORS; TREATMENT OUTCOME;

EID: 75449105273     PISSN: 15699293     EISSN: None     Source Type: Journal    
DOI: 10.1510/icvts.2009.220160     Document Type: Conference Paper

References (24)

1. Haemoglobin thresholds used to define anaemia. In: Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia. De Benoist, McLean, Egli Cogswell, editors. WHO. Switzerland, 2008;4.
2. Chaves PH, Xue QL, Guralnik JM, Ferrucci L, Volpato S, Fried LP. What constitutes normal hemoglobin concentration in community-dwelling disabled older women? J Am Geriatr Soc 2004;52:1811-1816.
3. Izaks GJ, Westendorp RGJ, Knook DL. The definition of anemia in older persons. J Am Med Assoc 1999;281:1714-1717.
4. Caramelo C, Justo S, Gil P. Anemia in heart failure: pathophysiology, pathogenesis, treatment, and incognitae. Rev Esp Cardiol 2007;60:848-860.
5. Go AS, Yang J, Ackerson LM, Lepper K, Robbins S, Massie BM, Shlipak MG. Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study. Circulation 2006;113:2713-2723.
6. Karkouti K, Wijeysundera DN, Beattie S. Reducing bleeding in cardiac surgery (RBC) investigators. Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study. Circulation 2008;117: 478-484.
7. DeFoe GR, Ross CS, Olmstead EM, Surgenor SD, Fillinger MP, Groom RC, Forest RJ, Pieroni JW, Warren CS, Bogosian ME, Krumholz CF, Clark C, Clough RA, Weldner PW, Lahey SJ, Leavitt BJ, Marrin CA, Charlesworth DC, Marshall P, O'Connor GT. Lowest hematocrit on bypass and adverse outcomes associated with coronary artery bypass grafting. Northern New England Cardiovascular Disease Study Group. Ann Thorac Surg 2001;71:769-776.
8. Kulier A, Levin J, Moser R, Rumpold-Seitlinger G, Tudor IC, Snyder-Ramos SA, Moehnle P, Mangano DT. Investigators of the Multicenter Study of Perioperative Ischemia Research Group, Ischemia Research and Education Foundation. Impact of preoperative anemia on outcome in patients undergoing coronary artery bypass graft surgery. Circulation 2007;116:471-479.
9. Cladellas M, Bruguera J, Comín J, Vila J, de Jaime E, Martí J, Gomez M. Is pre-operative anaemia a risk marker for in-hospital mortality and morbidity after valve replacement? Eur Heart J 2006;27:1093-1099.
10. Habib RH, Zacharias A, Schwann TA, Riordan CJ. The independent effects of cardiopulmonary bypass hemodilutional anemia and transfusions on CABG outcomes. Eur J Cardiothorac Surg 2005;28:512-513.
11. Patel KV, Guralnik JM. Prognostic implications of anemia in older adults. Haematologica 2009;94:1-2.
12. Milman N, Pedersen AN, Ovesen L, Schroll M. Hemoglobin concentrations in 358 apparently healthy 80-year-old Danish men and women. Should the reference interval be adjusted for age? Aging Clin Exp Res 2008; 20:8-14.
13. Ramel A, Jonsson PV, Bjornsson S, Thorsdottir I. Anemia, nutritional status, and inflammation in hospitalized elderly. Nutrition 2008;24: 1116-1122.
14. Beghé C, Wilson A, Ershler WB. Prevalence and outcomes of anemia in geriatrics: a systematic review of the literature. Am J Med 2004; 116(Suppl 7):3-10.
15. Zakai NA, Katz R, Hirsch C, Shlipak MG, Chaves PH, Newman AB, Cushman M. A prospective study of anemia status, haemoglobin concentration, and mortality in an elderly cohort. Arch Intern Med 2005; 165:2214-2220.
16. Wu WC, Schifftner TL, Henderson WG, Eaton CB, Poses RM, Uttley G, Sharma SC, Vezeridis M, Khuri SF, Friedmann PD. Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. J Am Med Assoc 2007;297:2481-2488.
17. Michalopoulos A, Tzelepis G, Dafni U, Geroulanos S. Determinants of hospital mortality after coronary artery bypass grafting. Chest 1999;115:1598-1603.
18. Rao S, Jollis J, Harrington R, Granger CB, Newby LK, Armstrong PW, Moliterno DJ, Lindblad L, Pieper K, Topol EJ, Stamler JS, Califf RM. Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes. J Am Med Assoc 2004;292:1555-1563.
19. Banbury MK, Brizzio ME, Rajeswaran J, Lytle BW, Blackstone EH. Transfusion increases the risk of postoperative infection after cardiovascular surgery. J Am Coll Surg 2006;202:131-138.
20. Surgenor SD, DeFoe GR, Fillinger MP, Likosky DS, Groom RC, Clark C, Helm RE, Kramer RS, Leavitt BJ, Klemperer JD, Krumholz CF, Westbrook BM, Galatis DJ, Frumiento C, Ross CS, Olmstead EM, O'Connor GT. Intraoperative red blood cell transfusion during coronary artery bypass graft surgery increases the risk of postoperative low-output heart failure. Circulation 2006;114(Suppl 1):I43-I48.
21. Koch CG, Li L, Duncan AI, Mihaljevic T, Loop FD, Starr NJ, Blackstone EH. Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Ann Thorac Surg 2006;81:1650-1657.
22. Engoren MC, Habib RH, Zacharias A, Schwann TA, Riordan CJ, Durham S. Effect of blood transfusion on long-term survival after cardiac operation. Ann Thorac Surg 2002;74:1180-1186.
23. Gardner TJ. To transfuse or not to transfuse. Circulation 2007;116:458-460.
24. Corwin HL, Gettinger A, Pearl RG, Fink MP, Levy MM, Abraham E, MacIntyre NR, Shabot MM, Duh MS, Shapiro MJ. The CRIT study: anemia and blood transfusion in the critically ill: current clinical practice in the United States. Crit Care Med 2004;32:39-52.