Pharmacokinetics evaluation of soft agglomerates for prompt delivery of enteric pantoprazole-loaded microparticles

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 2, 2010, Pages 275-280

  Raffin, Renata P ^a   Colomé, Letícia M ^a   Hoffmeister, Cristiane R D ^a   Colombo, Paolo ^b   Rossi, Alessandra ^b   Sonvico, Fabio ^b   Colomé, Lucas M ^c   Natalini, Claudio C ^a   Pohlmann, Adriana R ^a   Costa, Teresa Dalla ^a   Guterres, Silvia S ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSITY OF PARMA   (Italy)

^c UNIVERSITY OF PASSO FUNDO   (Brazil)

Author keywords

Agglomerates; Fast release; Microparticles; Pantoprazole; Pharmacokinetics

Indexed keywords

MANNITOL; NANOPARTICLE; PANTOPRAZOLE; PHOSPHATIDYLCHOLINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG HALF LIFE; ENTERIC COATED TABLET; FEMALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ADMINISTRATION, ORAL; ANIMALS; ANTI-ULCER AGENTS; BIOLOGICAL AVAILABILITY; DOGS; DRUG CARRIERS; DRUG COMPOUNDING; INTESTINAL ABSORPTION; MICROSPHERES; PARTICLE SIZE;

EID: 75449103931     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.11.015     Document Type: Article

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