Cryopreserved mesenchymal stromal cell treatment is safe and feasible for severe dilated ischemic cardiomyopathy

Cytotherapy

Volumn 12, Issue 1, 2010, Pages 31-37

  Chin, Sze Piaw ^a   Poey, Alfred C ^b   Wong, Chee Yin ^c   Chang, Sau Kong ^b   Teh, William ^b   Mohr, Teddric Jon ^b   Cheong, Soon Keng ^a  

^a INTERNATIONAL MEDICAL UNIVERSITY   (Malaysia)

^b Penang Adventist Hospital   (Malaysia)

^c Cytopeutics   (Malaysia)

Author keywords

Cryopreservation; Heart failure; Ischemic cardiomyopathy; Mesenchymal stromal cell

Indexed keywords

DIMETHYL SULFOXIDE;

ADULT; ARTICLE; BACTERIAL GROWTH; BONE MARROW BIOPSY; BONE MARROW CULTURE; CASE REPORT; CELL VIABILITY; CONGESTIVE HEART FAILURE; CORONARY ARTERY BYPASS GRAFT; CRYOPRESERVATION; DISEASE SEVERITY; FEASIBILITY STUDY; FUNGUS GROWTH; HEART ARRHYTHMIA; HEART FUNCTION; HEART VOLUME; HUMAN; HUMAN TISSUE; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE; PATIENT SAFETY; PRIORITY JOURNAL; SCAR FORMATION; SUPERNATANT; THAWING; THICKNESS; TREATMENT OUTCOME;

EID: 75449096581     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653240903313966     Document Type: Article

References (30)

1. Abdel-Latif A, Bolli R, Tleyjeh IM, Montori VM, Perin EC, Hornung CA, et al. Adult bone marrow derived cells for cardiac repair: a systematic review and metaanalysis. Arch Int Med 2007;167:989-997
2. Schachinger V, Erbs S, Elsasser A, Haberbosch W, Hambrecht R, Holschermann H, et al. Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Eng J Med 2006;355:1210-1221 (Pubitemid 44427445)
3. Assmus B, Schachinger V, Teupe C, Britten M, Lahmann R, Dobert N, et al. Transplantation of progenitor cells and rengeneration enhancement in acute myocardial infarction (TOPCARE-AMI). Circulation 2002;106:3009-3017
4. Pittenger MF, Bradley JM. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 2004;95:9-20.
5. Minguell JJ, Erics A. Mesenchymal stem cells and the treatment of cardiac disease. Exp Biol Med 2006:231: 39-49.
6. Toma C, Pittenger MF, Cahill KS, Byrne BJ, Kessler PD. Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002;105:93-98
7. Chen SL, Fang WW, Ye F, Liu YH, Qian J, Shan SJ, et al. Effect on left ventricular function of intra-coronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol 2004;94:92-95 (Pubitemid 38813459)
8. Katritsis DG, Sotiropoulou PA, Karvouni E, Karabinos I, Karovesis S, Perez SA, et al. Transcoronary transplantation of autologous mesenchymal stem cells and endothelial progenitors into infracted human myocardium. Catheter Cardiovasc Interven 2005;65:321-329
9. Mohyeddin-Bonab M, Mohamad-Hasani MR, Alimogaddam K, Sanatkar M, Gasemi M, Mirhhani H, et al. Autologous in vitro expanded mesenchymal stem cell therapy for human old myocardial infarction. Arch Iranian Med 2007;10:467-473
10. Rubinstein P, Dobrila L, Rosenfield RE, Adamson JW, Migliaccio G, Migliaccio AR, et al. Processing and cryopreservation of placental/umbilical cord blood for unrelated bone marrow reconstitution. Proc Natl Acad Sci USA 1995; 92:10119-10122
11. Meyer TPH, Hofmann B, Zaisserer J, Jacobs V, Fuchs B, Rapp S, et al. Analysis and cryopreservation of hematopoietic stem and progenitor cells from umbilical cord blood. Cytotherapy 2006;8:265-276
12. Galmes A, Gutierrez A, Sampol A, Canaro M, Morey M, Iglesias J, et al. Long-term hematologic reconstitution and clinical evaluation of autologous peripheral blood stem cell transplantation after cryopreservation of cells with 5% and 10% dimethylsulfoxide at -80°C in a mechanical freezer. Haematologica 2007;92:986-989
13. Nagamura-Inoue T, Shioya M, Sugo M, Cui Y, Takahashi A, Tomita S, et al. Wash-out of DMSO does not improve the speed of engraftment of cord blood transplantation: follow-up of 46 adult patients with units shipped from a single cord blood bank. Transfusion 2003;43:1285-1295
14. Haack-Sorensen M, Bindslev L, Mortensen S, Friis T, Kastrup J. The influence of freezing and storage on the characteristics and functions of human mesenchymal stromal cells isolated for clinical use. Cytotherapy 2007; 9:328-337
15. Casado-Diaz A, Santiago-Mora R, Jimenez R, Caballero-Villarraso J, Herrera C, Torres A, et al. Cryopreserved human bone marrow mononuclear cells as a source of mesenchymal stromal cell: application in osteoporosis research. Cytotherapy 2008;10:460-468
16. Reger RL, Wolfe MR. Freezing harvested hMSCs and recovery of hMSCs from frozen vials for subsequent expansion, analysis, and experimentation. Methods Mol Biol 2008;449:109-116
17. Samuelsson H, Ringden O, Lonnies H, Le Blanc K. Optimizing in vitro conditions for immunodulation and expansion of mesenchymal stromal cells. Cytotherapy 2009; 11:129-136
18. Wong CY, Cheong SK, Mok PL, Leong CF. Differentiation of human mesenchymal stem cells into mesangial cells in post-glomerular injury murine model. Pathology 2008;40: 52-57
19. Mok PL, Leong CF, Cheong SK. Isolation and identification of putative mesenchymal stem cells from bone marrow. Malays J Pathol 2003;25:121-127
20. Law PK, Chin SP, Hung HD, Nguyen TN, Feng QZ. Delivery of biologics for angiogenesis and myogenesis. In: Nguyen TN, Colombo A, Hu D, Grines CL, Saito S. Practical Handbook of Advanced Interventional Cardiology, 3rd edn. Blackwell; 2008. p. 583-595
21. Le Blanc K, Frassoni F, Ball L, Locatelli F, Roelofs H, Lewis I, et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-vesus-host disease: a phase II study. Lancet 2008;371:1579-1586
22. Bang YO, Lee SJ, Lee PH, Lee G. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 2005;57:874-882
23. Moviglia GA, Fernandez Viña R, Brizuela JA, Saslavsky J, Vrsalovic F, Varela G, et al. Combined protocol of cell therapy for chronic spinal cord injury. Report on the electri-cal and functional recovery of two patients. Cytotherapy 2006;8:202-209
24. Le Blanc K, Gottherstrom C, Ringden O, Hassan M, McMahon R, Horwitz E, et al. Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta. Transplantation 2005;79: 1607-1614
25. Horwitz EM, Gordon PL, Koo WKK, Marx JC, Neel MD, McNall RY, et al. Isolated allogeneic bone marrow-derived mesenchymal stem cells engraft and stimulate growth in children with osteogenesis imperfecta: implication for cell therapy of bone. Proc Natl Acad Sci USA 2002;99: 8932-8937
26. Wakitani S, Imoto K, Yamamoto T, Saito M, Murata N, Yoneda M. Human autologous culture expanded bone marrow mesenchymal stem cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritis Cartilage 2002;1:199-206.
27. Petropoulou AD, Bellochine R, Norol F, Marie JP, Rio B. Coronary artery spasm after infusion cryopreserved cord blood cells. Bone Marrow Transplant 2007;40:397-398
28. Hubel A. Cryopreservation of HPCs for clinical use. Transfusion 2001;41:579-580
29. Syme R, Bewick M, Stewart D, Porter K, Chadderton T, Glück S. The role of depletion of dimethyl sulfoxide before autografting: on hematologic recovery, side effects, and toxicity. Biol Blood Marrow Transplant 2004;10:135-141
30. Windrum P, Morris TCM, Drake MB, Niederwieser D, Ruutu T. Variation in dimethyl sulfoxide use in stem cell transplantation: a survey of EBMT centres. Bone Marrow Transplant 2005;36:601-603