Apocynin attenuate spatial learning deficits and oxidative responses to intermittent hypoxia

Sleep Medicine

Volumn 11, Issue 2, 2010, Pages 205-212

  Hui guo, Liu ^a   Kui, Liu ^a   Yan ning, Zhou ^a   Yong jian, Xu ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apocynin; Intermittent hypoxia; NADPH oxidase; Oxidative stress; P22phox; P47phox; Spatial learning

Indexed keywords

APOCYNIN; MALONALDEHYDE; MESSENGER RNA; PROTEIN P22; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HIPPOCAMPUS; HYPOXIA; LEARNING DISORDER; MALE; MAZE TEST; NONHUMAN; OXIDATIVE STRESS; PRIMARY PREVENTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ACETOPHENONES; ANIMALS; ANOXIA; BLOTTING, WESTERN; HIPPOCAMPUS; IN SITU NICK-END LABELING; MALE; MALONDIALDEHYDE; MAZE LEARNING; NADPH OXIDASE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE;

EID: 75449093386     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2009.05.015     Document Type: Article

References (51)

1. Wiegand L., and Zwillich C.W. Obstructive sleep apnea. Dis Mon 40 (1994) 197-252
2. Redline S., and Strohl K.P. Recognition and consequences of obstructive sleep apnea hypopneas syndrome. Clin Chest Med 19 (1998) 1-19
3. Gozal D. Morbidity of obstructive sleep apnea in children: facts and theory. Sleep Breath 5 (2001) 35-42
4. Young T., Palta M., Dempsey J., et al. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328 (1993) 1230-1235
5. Adams N., Strauss M., Schluchchter M., et al. Relation of measures of sleep-disordered breathing to neuropsychological functioning. Am J Respir Crit Care Med 163 (2001) 1626-1631
6. Veasey S.C., Davis C.W., Fenik P., et al. Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions. Sleep 27 (2004) 194-201
7. Row B.W., Kheirandish L., Neville J.J., et al. Impaired spatial learning and hyperactivity in developing rats exposed to intermittent hypoxia. Pediatr Res 52 (2002) 449-453
8. Gozal E., Row B.W., Schurr A., et al. Development differences in cortical and hippocampal vulnerability to intermittent hypoxia in the rat. Neurosci Lett 305 (2001) 197-201
9. Kadar T., Dachir S., Shukitt-Hale B., et al. Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction. J Neural Transm 105 (1998) 987-1004
10. Beal M.F. Aging, energy, and oxidative stress in neurodegenerative diseases. Am Neurol 38 (1995) 357-366
11. Kohmura E., Yamada K., Hayakawa T., et al. Hippocampal neurons become more vulnerable to glutamate after subcritical hypoxia: an in vitro study. J Cereb Blood Flow Metab 10 (1990) 877-884
12. Mark R.J., Lovell M.A., Markeabery W.R., et al. A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide. J Neurochem 68 (1997) 255-264
13. Nicolle M.M., Gonzalez J., Sugaya K., et al. Signatures of hippocampal oxidative stress in aged spatial learning-impaired rodent. Neuroscience 107 (2001) 415-431
14. Nicholls D., and Attwell D. The release and uptake of excitatory amino acids. Trends Pharmacol Sci 11 (1990) 462-468
15. Horakova L., Stolc S., Chromikova Z., et al. Mechanisms of hippocampal reoxygenation injury. Mol Chem Neurochem 33 (1998) 223-236
16. Katsura K., Rodriguez S., Smith D., et al. Coupling among energy failure, loss of ion homeostasis, and phospholipase A2 and C activation during ischemia. J Neurochem 61 (1993) 1677-1684
17. Siesjo B.K., Rehncrona S., and Smith D. Neuronal cell damage in the brain: possible involvement of oxidative mechanisms. Acta Physiol Scand Suppl 492 (1980) 121-128
18. Ozaki M., Deshpande S.S., Angkeow P., et al. Inhibition of the Rac1 GTP are protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo. FASEB J 14 (2000) 418-429
19. Harada H., Hines I.N., Flores S., et al. Role of NADPH oxidase-derived superoxide in reduced size liver ischemia and reperfusion injury. Arch Biochem Biophys 423 (2004) 103-108
20. Kusaka I., Kusaka G., Zhou C., et al. Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury. Am J Physiol Heart Circ Physiol 286 (2004) H2442-H2451
21. Rupin A., Paysant J., Sansilvestri-Morel P., et al. Role of NADPH oxidase-mediated superoxide production in the regulation of E-selectin expression by endothelial cells subjected to anoxia/reoxygenation. Cardiovasc Res 63 (2004) 323-330
22. Abramov A.Y., Canevari L., and Duchen M.R. Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase. J Neurosci 24 (2004) 565-575
23. Jana A., and Pahan K. Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease. J Biochem (Tokyo) 279 (2004) 51451-51459
24. Gao H.M., Liu B., Zhang W., et al. Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease. FASEB J 17 (2003) 1954-1956
25. Wu D.C., Teismann P., Tieu K., et al. NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine model of Parkinson's disease. Proc Natl Acad Sci USA 100 (2003) 6145-6150
26. Zhang W., Wang T., Qin L., et al. Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase. FASEB J 18 (2004) 589-591
27. Noh K.M., and Koh J.Y. Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes. J Neurosci 20 (2000) RC111
28. Serrano F., Kolluri N.S., Wientjes F.B., et al. NADPH oxidase immunoreactivity in the mouse brain. Brain Res 988 (2003) 193-198
29. Wang G., Anrather J., Huang J., et al. NADPH oxidase contributes to angiotensin II signaling in the nucleus tractus solitarius. J Neurosci 24 (2004) 551-5524
30. imons J.M., 't Hart B.A., Ip Vai Ching R.A.M., et al. Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils. Free Rad Biol Med 8 (1990) 251-258
31. Beukelman C.J., Van den Berg A.J.J., Kroes B.H., et al. Plant-derived metabolites with synergistic antioxidant activity. Immunol Today 16 (1995) 108
32. Stolk J., Hiltermann J.T.N., Dijkman J.H., et al. Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin a methoxy substituted catechol. Am J Respir Cell Mol Biol 11 (1994) 95-102
33. Cifuentes M.E., and Pagano P.J. Targeting reactive oxygen species in hypertension. Curr Opin Nephrol Hypertens 15 2 (2006) 179-186
34. Ushio-Fukai M., Zafari A.M., Fukui T., Ishizaka N., and Griendling K.K. P22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells. J Biol Chem 271 (1996) 23317-23321
35. Gozal D., Daniel J.M., Dohanich G.P., et al. Behavioral and anatomical correlates of chronic episodic hypoxia during sleep in the rat. J Neurosci 21 (2001) 2442-2450
36. Decary A., Rouleau I., and Montplaisir J. Cognitive deficits associated with sleep apnea syndrome: a proposed neuropsychological test battery. Sleep 23 (2000) 369-381
37. Vgontzas A.N., Bixler E.O., and Chrousos G.P. Sleep apnea is a manifestation of the metabolic syndrome. Sleep Med Rev 9 (2005) 211-224
38. Punjabi N.M., Ahmed M.M., Polotsky V.Y., et al. Sleep-disordered breathing, glucose intolerance, and insulin resistance. Respir Physiol Neurobiol 136 (2003) 167-178
39. Anstead M., and Phillips B. The spectrum of sleep-disordered breathing. Respir Care Clin N Am 5 (1999) 363-377
40. Gozal D., Row B.W., Gozal E., et al. Temporal aspects of spatial task performance during intermittent hypoxia in the rat: evidence for neurogenesis. Eur J Neurosci 18 (2003) 2335-2342
41. Row B.W., Liu R., Xu W., et al. Intermittent hypoxia is associated with oxidative stress and spatial learning deficits in the rat. Am J Respir Crit Care Med 167 (2003) 1548-1553
42. Zhan G., Fenik P., Pratico D., et al. Inducible nitric oxide synthase in long-term intermittent hypoxia: hypersomnolence and brain injury. Am J Respir Crit Care Med 171 (2005) 1414-1420
43. Zhan G., Serrano F., Fenik P., et al. NADPH oxidase mediates hypersomnolence and brain oxidative injury in a murine model of sleep apnea. Am J Respir Crit Care Med 172 (2005) 921-929
44. Li R.C., Row B.W., Kheirandish L., et al. Nitric oxide synthase and intermittent hypoxia-induced spatial learning deficits in the rat. Neurobiol Dis 17 (2004) 44-53
45. Li R.C., Row B.W., Gozal E., et al. Cyclooxygenase 2 and intermittent hypoxia-induced spatial deficits in the rat. Am J Respir Crit Care Med 168 (2003) 469-475
46. Eu J.P., Liu L., Zeng M., et al. An apoptotic model for nitrosative stress. Biochemistry 39 (2000) 1040-1047
47. Farooqui A.A., Horrocks L.A., and Farooqui T. Modulation of inflammation in brain: a matter of fat. J Neurochem 101 (2007) 577-599
48. Isler M., Delibas N., Guclu M., et al. Superoxid dismutase and glutathione peroxidase in erythrocytes of patients with iron deficiency anemia: effect of different treatment modalities. Croat Med J 43 (2002) 16
49. Abramov A.Y., Jacobson J., Wientjes F., et al. Expression and modulation of an NADPH oxidase in mammalian astrocytes. J Neurosci 25 (2005) 9176-9184
50. Touyz R.M., Chen X., Tabet F., et al. Expression of a functionally active gp91phox-containing neutrophil-type NADPH oxidase in smooth muscle cells from human resistance arteries: regulation by an giotensin II. Cire Res 90 (2002) 1205-1213
51. Jones R.D., Hancock J.T., and Morice A.H. NADPH oxidase: a universal oxygen sensor?. Free Radic Biol Med 29 (2000) 416-424