Grief, demoralization, and depression: Diagnostic challenges and treatment modalities

Primary Psychiatry

Volumn 16, Issue 5, 2009, Pages 49-55

  Strada, E Alessandra ^a,b  

^a BETH ISRAEL MEDICAL CENTER   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ESCITALOPRAM; PAROXETINE;

BEREAVEMENT; CLINICAL FEATURE; COGNITIVE THERAPY; COMPLICATED GRIEF; CRITICALLY ILL PATIENT; DEMORALIZATION SYNDROME; DEPRESSION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DIFFERENTIAL DIAGNOSIS; DYING; EMOTIONAL STRESS; FAMILY COUNSELING; FAMILY THERAPY; GRIEF; HOPELESSNESS; HUMAN; PATIENT EDUCATION; PSYCHOTHERAPY; REVIEW; SOCIAL SUPPORT; TERMINAL CARE; TREATMENT INDICATION;

EID: 75449089213     PISSN: 10826319     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (72)

1. Clieren M. Bereavement and Adaptation: A Comparative Study of the Aftermath of Death. Washington, DC: Hemisphere Publishing Corporation; 1993.
2. Raphael B, Dobson M. Bereavement. In: Harvey JH, Miller ED, eds. Loss and Trauma. Philadelphia, PA: Brunner Routledge Publishers; 2000:45-61.
3. Sprang G, McNeil J. The Many Faces of Bereavement: The Nature and Treatment of Natural, Traumatic, and Stigmatized Grief. New York, NY: Brunner/Mazel Publishers; 1995.
4. Abi-Hashem N. Grief, Loss, and Bereavement: An Overview. New York, NY: Little, Brown; 1999.
5. Attig T. How We Grieve: Relearning the World. New York, NY: Oxford University Press; 1996.
6. Cottington EM, Matthews KA, Talbott E, Kuller LH. Environmental events preceding sudden death in women. Psychosom Med. 1980;42(6):567-574.
7. Lindstrom TC. Immunity and health after bereavement in relation to coping. Scand J Psychol. 1997;38(3):253-259.
8. Manor O, Eisenbach Z. Mortality after spousal loss: are there socio-demographic differences? Soc Sci Med. 2003;56(2):405-413.
9. Hart CL, Hole DJ, Lawlor DA, Smith GD, Lever TF. Effect of conjugal bereavement on mortality of the bereaved spouse in participants of the Renfrew/Paisley Study. J Epidemiol Community Health. 2007;61(5):455-460.
10. Espinosa J, Evans WN. Heightened mortality after the death of a spouse: marriage protection or marriage selection? J Health Econ. 2008;27(5):1326-1342.
11. Helsing KJ, Szklo M. Mortality after bereavement. Am J Epidemiol. 1981;114:1:41-52.
12. Jones DR, Goldblatt PO. Causes of death in widowers and spouses. J Biosoc Sci. 1987;19:107-121.
13. Ajdacic-Gross V, Ring M, Gadola E, et al. Suicide after bereavement: an overlooked problem. Psychol Med. 2008;38(5):673-676.
14. Erlangsen A, Jeune B, Bille-Brahe U, Vaupel JW. Loss of partner and suicide risks among oldest old: a population-based register study. Age Ageing. 2004;33(4):378-383.
15. Zhang B, Mitchell SL, Bambauer KZ, Jones R, Prigerson HG. Depressive symptoms trajectories and associated risks among bereaved Alzheimer disease caregivers. Am J Geriatr Psychiatry. 2008;16(2):145-155.
16. Macias C, Jones D, Harvey J, Barreira P, Harding C, Rodican C. Bereavement in the context of serious mental illness. Psychiatr Serv. 2004;55(4):421-426.
17. Nolen-Hoeksema S, Larson J. Coping with Loss. London, UK: Lawrence Erlbaum Associates; 1999.
18. Murphy SA, Johnson LC, Chung IJ, Beaton RD. The prevalence of PTSD following the violent death of a child and predictors of change 5 years later. J Trauma Stress. 2003;16(1):17-25.
19. Lindemann E. Symptomatology and management of acute grief. Am J Psychiatry. 1944;101:141-148.
20. Bowlby J. Attachment and Loss III: Loss, Sadness, and Depression. London, UK: The Hogarth Press; 1980.
21. Parkes CM. Bereavement: Studies of Grief in Adult Life. Madison, CT: International University Press; 1987.
22. Stroebe MS, Stroebe WW, Hanson RO. Handbook of Bereavement. New York, NY: Cambridge University Press; 1993.
23. Rando T. Treatment of Complicated Mourning. Champaign, IL: Research Press Company; 1993.
24. Stroebe M, Schut H, Stroebe W. Health outcomes of bereavement. Lancet. 2007;370:9603:1960-1973.
25. Prigerson HG, Frank E, Kasl SV, et al. Complicated grief and bereavement-related depression as distinct disorders: preliminary empirical validation in elderly bereaved spouses. Am J Psychiatry. 1995;152(1):22-30.
26. Dillen L, Fontaine JR, Verhofstadt-Deneve L. Are normal and complicated grief different constructs? A confirmatory factor analytic test. Clin Psychol Psychother. 2008;15(6):386-395.
27. Simon NM, Shear KM, Thomson EH, et al. The prevalence and correlates of psychiatric morbidity in individuals with complicated grief. Compr Psychiatry. 2007;48(5):395-399.
28. Horowitz MJ, Siegel B, Holen A, Bonanno GA, Milbrath C, Stinson CH. Diagnostic criteria or complicated grief disorder. Am J Psychiatry. 1997;154(7):904-910.
29. Zhang B, El-Jawahri A, Prigerson HG. Update on bereavement research: evidence-based guidelines for the diagnosis and treatment of complicated bereavement. J Palliat Med. 2006;9(5):1188-1203.
30. Boelen PA, Prigerson HG. The influence of symptoms of prolonged grief disorder, depression, and anxiety on quality of life among bereaved adults: a prospective study. Eur Arch Psychiatry Clin Neurosci. 2007;257(8):444-452.
31. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington, DC: American Psychiatric Association; In Press.
32. Mystakidou K, Tsilika E, Parpa E, Galanos A, Vlahos L. Screening for preparatory grief in advanced cancer patients. Cancer Nurs. 2008;31(4):326-332.
33. Mystakidou K, Parpa E, Tsilika E, et al. Preparatory grief, psychological distress and hopelessness in advanced cancer patients. Eur J Cancer Care (Engl). 2008;17(2):145-151.
34. Ventafridda V, Ripamonti C, De Conno F, Tamburini M, Cassileth BR. Symptom prevalence and control during cancer patients last days of life. J Palliat Care. 1990;6(3):7-11.
35. Periyakoil VS, Hallenbeck J. Identifying and managing preparatory grief and depression at the end of life. Am Fam Physician. 2002;65(5):883-890.
36. Kubler-Ross E. On Death and Dying: What the Dying Have to Teach Doctors, Nurses, Clergy, and Their Families. New York, NY: Simon and Schuster; 1997.
37. Axtell A. Depression in palliative care. J Palliat Med. 2008;11:(3):529-530.
38. Worden JW. Grief Counseling and Grief Therapy. New York, NY: Springer Publishing Company; 2002.
39. Glaser BG, Straus AL. Awareness of Dying. Chicago, IL: Aldine; 1965.
40. Shear K, Frank E, Houck PR, Reynolds CF 3rd. Treatment of complicated grief: a randomized controlled trial. JAMA. 2005;293(21):2601-2608.
41. Simon NM, Shear MK, Fagiolini A, et al. Impact of concurrent naturalistic pharmacotherapy on psychotherapy of complicated grief. Psychiatry Res. 2008;159(1-2):31-36.
42. Piper WE, Ogrodniczuk JS, Joyce AS, Weideman R, Rosie JS. Group composition and group therapy for complicated grief. J Consult Clin Psychol. 2007;75(1):116-125.
43. Sikkema KJ, Hansen NB, Ghebremichael M, et al. A randomized controlled trial of a coping group intervention for adults with HIV who are AIDS bereaved: longitudinal effects on grief. Health Psychol. 2006;25(5):563-570.
44. Simon NM, Thomson EH, Pollack MH, Shear MK. Complicated grief: a case series using escitalopram. Am J Psychiatry. 2007;164(11):1760-1761.
45. Zisook S, Shuchter SR, Pedrelli P, Sable J, Deaciuc SC. Bupropion sustained release for bereavement: results of an open trial. J Clin Psychiatry. 2001;62(4):227-230.
46. Zygmont M, Prigerson HG, Houck PR, et al. A post hoc comparison of paroxetine and nortriptyline for symptoms of traumatic grief. J Clin Psychiatry. 1998;59(5):241-245.
47. Simon NM, Thompson EH, Pollack MH, Shear MK. Complicated grief: a case series using escitalopram. Am J Psychiatry. 2007;164(11):1760-1761.
48. Kissane DW, Bloch S. Family grief. Br J Psychiatry. 1994;164(6):720-740.
49. EPEC/Institute for Ethics at the American Medical Association. Education for Physicians on End-of-life Care. Chicago, IL: American Medical Association; 2000.
50. Taylor V, Ashelford S. Understanding depression in palliative and end-of-life care. Nurs Stand. 2008;23(12):48-57.
51. Irwin SA, Ferris FD. The opportunity for psychiatry in palliative care. Can J Psychiatry. 2008;53(11):713-724.
52. Rodin G, Lo C, Mikulincer M, Donner A, Gagliese L, Zimmermann C. Pathways to distress: the multiple determinants of depression, hopelessness, hopelessness, and the desire for hastened death in metastatic cancer patients. Soc Sci Med. 2009;68(3):562-569.
53. Nazneen HN, Montagnini M. Recognizing depression in palliative care patients. J Pall Med. 2007;10(2):458-464.
54. Block SD. Assessing and managing depression in the terminally ill patient. ACP-ASIM End-of-Life Care Consensus Panel. American College of Physicians - American Society of Internal Medicine. Ann Intern Med. 2000;132(3):209-218.
55. Lloyd-Williams M, Dennis M, Taylor F. A prospective study to compare three depression screening tools in patients who are terminally ill. Gen Hosp Psychiatry. 2004;26(5):384-389.
56. Diagnostic and Statistical Manual of Mental Disorders. 4th ed, text rev. Washington, DC: American Psychiatric Association; 2000.
57. Lloyd-Williams M. Friedman T, Rudd N. An analysis of the validity of the hospital anxiety and depression scale as a screening tool in patients with advanced metastatic cancer. J Pain Symptom Manage. 2001;22(6):990-996.
58. Goy E, Ganzini L. End-of-life care in geriatric psychiatry. Clin Geriatr Med. 2003; 19:(4):841-856.
59. Robinson MJ, Owen JA. Psychopharmacology. In: Levenson J, ed. The American Psychiatric Publishing Textbook of Psychosomatic Medicine. Washington, DC: American Psychiatric Press; 2004:871.
60. Akechi T, Okuyama T, Onishi J, Morita T, Furukawa TA. Psychotherapy for depression among incurable cancer patients. Cochrane Database Syst Rev. 2008;(2):CD005537.
61. Massie M, Holland JC, Straker N. Psychotherapeutic interventions. In: Holland JC, Rowland JR, eds. Handbook of Psychooncology: Psychological Care of the Patient with Cancer. New York, NY: Oxford University Press; 1990:455-469.
62. Frank J. The role of hope in psychotherapy. Int J Psychiatry. 1968;5(5):383-395.
63. De Figueiredo JM. Demoralization and psychotherapy: a tribute to Jerome D. Frank, MD, PhD (1909-2005). Psychother Psychosom. 2007;76(3):129-133.
64. Engel GL. A psychological setting of somatic disease: the "giving up-given up complex". Proc R Soc Med. 1967;60:553-555.
65. Kissane DW, Clarke DM, Street AF. Demoralization syndrome: a relevant psychiatric diagnosis for palliative care. J Palliat Care. 2001;17:(1):12-21.
66. Clarke DM, Kissane DW. Demoralization: its phenomenology and importance. Aust N Z J Psychiatry. 2002;36(6):733-42.
67. Kissane DW. The contribution of demoralization to end-of-life decision making. Hastings Cent Rep. 2004;34(4):21-31.
68. Lloyd-Williams M, Reeve J, Kissane D. Distress in palliative care patients: developing patient-centred approaches to clinical management. Eur J Cancer. 2008;44(8):1133-1138.
69. Angelino AF, Treishman GJ. Major depression and demoralization in cancer patients: diagnostic and treatment considerations. Support Care Cancer. 2001;9(5):344-349.
70. Reeve JL, Lloyd-Williams M, Dowrick C. Rivisiting depression in palliative care settings: the need to focus on clinical utility over validity. Palliat Med. 2008;22(4):383-391.
71. Mangelli L, Fava GA, Grandi S, et al. Assessing demoralization and depression in the setting of medical disease. J Clin Psychiatry. 2005;66(3):391-394.
72. Marchesi C, Maggini C. Socio-demographic and clinical features associated with demoralization in medically ill in-patients. Soc Psychiatry Psychiatr Epidemiol. 2007;42(10):824-829.