Cisplatin-mediated selective hydrolytic cleavage of methionine-containing peptides with neighboring serine or histidine residues

Journal of Inorganic Biochemistry

Volumn 98, Issue 11, 2004, Pages 1947-1956

  Manka, Sven ^a   Becker, Friederike ^a   Hohage, Oliver ^a   Sheldrick, William S ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Cisplatin; Histidine; Methionine; Peptide cleavage; Serine

Indexed keywords

ACETIC ACID; ACETIC ACID DERIVATIVE; ACID; AMIDE; ANTINEOPLASTIC AGENT; CISPLATIN; GLYCINE; HISTIDINE; METHIONINE; METHIONINE DERIVATIVE; METHIONINE SULFUR; N ACETYLMETHIONINE; NITROGEN DERIVATIVE; PEPTIDE DERIVATIVE; SERINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG SELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PH; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; SEQUENCE ANALYSIS; TIME;

AMINO ACID SEQUENCE; CISPLATIN; DIPEPTIDES; HISTIDINE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; METHIONINE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PEPTIDES; SERINE;

EID: 7544239416     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2004.08.016     Document Type: Article

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