A generalized numerical approach to steady-state enzyme kinetics: Applications to protein kinase inhibition

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1804, Issue 3, 2010, Pages 635-641

  Kuzmič, Petr ^a  

^a BioKin Ltd   (United States)

Author keywords

Bisubstrate analog; DYNAFIT; Enzyme kinetics; Inhibition; p56lck tyrosine kinase; PKA; Protein Kinase; Steady state approximation; Theory

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEIN KINASE; PROTEIN P56;

ARTICLE; COMPUTER PROGRAM; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; MATHEMATICAL MODEL; PRIORITY JOURNAL; STEADY STATE; STOICHIOMETRY; THERMODYNAMICS;

ADENOSINE TRIPHOSPHATE; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MODELS, CHEMICAL; PROTEIN KINASE INHIBITORS;

EID: 75349106266     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.07.028     Document Type: Article

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