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Volumn 113, Issue 1, 2009, Pages 116-126

P19 neuronal differentiation and retinoic acid metabolism as criteria to investigate atrazine, nitrite, and nitrate developmental toxicity

Author keywords

Agrochemical contaminants; Bioassay; Flow cytometry; HPLC; Retinoids

Indexed keywords

ATRAZINE; NITRATE; NITRITE; NITROGEN FERTILIZER; RETINOIC ACID; RETINOID; STAGE SPECIFIC EMBRYO ANTIGEN 1; TUBULIN;

EID: 75249107457     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp243     Document Type: Article
Times cited : (12)

References (63)
  • 1
    • 0034818449 scopus 로고    scopus 로고
    • Effects of atrazine on embryos, larvae, and adults of anuran amphibians
    • Allran, J.W., and Karasov, W.H. (2001). Effects of atrazine on embryos, larvae, and adults of anuran amphibians. Environ. Toxicol. Chem. 20, 769-775.
    • (2001) Environ. Toxicol. Chem. , vol.20 , pp. 769-775
    • Allran, J.W.1    Karasov, W.H.2
  • 2
    • 0028010247 scopus 로고
    • The effects of nitrate on tadpoles of the tree frog (Litoria caerulea)
    • Baker, J., and Waights, V. (1994). The effects of nitrate on tadpoles of the tree frog (Litoria caerulea). Herpetol. J. 4, 106-108.
    • (1994) Herpetol. J. , vol.4 , pp. 106-108
    • Baker, J.1    Waights, V.2
  • 3
    • 11844273815 scopus 로고    scopus 로고
    • Plasma retinoid profile in bullfrogs, Rana catesbeiana, in relation to agricultural intensity of sub-watersheds in the Yamaska River drainage basin, Québec
    • Bérubé, V. E., Boily, M.H., DeBlois, C., Dassylva, N., and Spear, P.A. (2005). Plasma retinoid profile in bullfrogs, Rana catesbeiana, in relation to agricultural intensity of sub-watersheds in the Yamaska River drainage basin, Québec, Canada. Aquat. Toxicol. 71, 109-120.
    • (2005) Canada. Aquat. Toxicol. , vol.71 , pp. 109-120
    • Bérubé, V.E.1    Boily, M.H.2    DeBlois, C.3    Dassylva, N.4    Spear, P.A.5
  • 4
    • 58149513767 scopus 로고    scopus 로고
    • Retinoid metabolism (LRAT, REH) in the liver and plasma retinoids of bullfrog, Rana catesbeiana, in relation to agricultural contamination
    • (special issue Amphib. Toxicol.)
    • Boily, M., Thibodeau, J., and Bisson, M. (2009). Retinoid metabolism (LRAT, REH) in the liver and plasma retinoids of bullfrog, Rana catesbeiana, in relation to agricultural contamination. Aquat. Toxicol. (special issue Amphib. Toxicol.) 91, 118-125.
    • (2009) Aquat. Toxicol. , vol.91 , pp. 118-125
    • Boily, M.1    Thibodeau, J.2    Bisson, M.3
  • 6
    • 0037231686 scopus 로고    scopus 로고
    • Retinoidmetabolism (LRAT REH) in the yolk-sac membrane of Japanese quail eggs and effects of mono-ortho-PCBs
    • Boily, M.H., Ndayibagira, A., andSpear, P.A.(2003).Retinoidmetabolism (LRAT, REH) in the yolk-sac membrane of Japanese quail eggs and effects of mono-ortho-PCBs. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 134, 11-23.
    • (2003) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.134 , pp. 11-23
    • Boily, M.H.1    Ndayibagira, A.2    Spear, P.A.3
  • 7
    • 64349114023 scopus 로고    scopus 로고
    • Embryonic stem cell test remastered: Comparison between the validated EST and the new molecular FACS-EST for assessing developmental toxicity in vitro
    • Buesen, R., Genschow, E., Slawik, B., Visan, A., Spielmann, H., Luch, A., and Seiler, A. (2009). Embryonic stem cell test remastered: Comparison between the validated EST and the new molecular FACS-EST for assessing developmental toxicity in vitro. Toxicol. Sci. 108, 389-400.
    • (2009) Toxicol. Sci. , vol.108 , pp. 389-400
    • Buesen, R.1    Genschow, E.2    Slawik, B.3    Visan, A.4    Spielmann, H.5    Luch, A.6    Seiler, A.7
  • 8
    • 0034647096 scopus 로고    scopus 로고
    • Conversion and storage of somatostatin are established before response to secretagogue stimuli in P19 neurons
    • Cadet, N., and Paquin, J. (2000). Conversion and storage of somatostatin are established before response to secretagogue stimuli in P19 neurons. Brain Res. Dev. Brain Res 120, 211-221.
    • (2000) Brain Res. Dev Brain Res. , vol.120 , pp. 211-221
    • Cadet, N.1    Paquin, J.2
  • 9
    • 28844448724 scopus 로고    scopus 로고
    • Effect of carbamate esters on neurite outgrowth in differentiating human SK-N-SH neuroblas-toma cells
    • Chang, P.-A., Wu, Y.-J., Li, W., and Leng, X.-F. (2006). Effect of carbamate esters on neurite outgrowth in differentiating human SK-N-SH neuroblas-toma cells. Chem. Biol. Interact. 159, 65-72.
    • (2006) Chem. Biol. Interact. , vol.159 , pp. 65-72
    • Chang, P.-A.1    Wu, Y.-J.2    Li, W.3    Leng, X.-F.4
  • 10
    • 33847005103 scopus 로고    scopus 로고
    • Dopaminergic toxicity associated with oral exposure to the herbicide atrazine in juvenile male C57BL/6 mice
    • Coban, A., and Filipov, N.M. (2007). Dopaminergic toxicity associated with oral exposure to the herbicide atrazine in juvenile male C57BL/6 mice. J. Neurochem. 100, 1177-1187.
    • (2007) J. Neurochem. , vol.100 , pp. 1177-1187
    • Coban, A.1    Filipov, N.M.2
  • 12
    • 0141543935 scopus 로고    scopus 로고
    • Stream transport of herbicides and metabolities in a tile-drained, agricultural watershed
    • David, M.B., Gentry, L.E., Starks, K.M., and Cooke, R.A. (2003). Stream transport of herbicides and metabolities in a tile-drained, agricultural watershed. J. Environ. Qual. 32, 1790-1801.
    • (2003) J. Environ. Qual. , vol.32 , pp. 1790-1801
    • David, M.B.1    Gentry, L.E.2    Starks, K.M.3    Cooke, R.A.4
  • 15
    • 26444553653 scopus 로고    scopus 로고
    • Immunotoxic effects of short-term atrazine exposure in young male C57Bl/6 mice
    • Filipov, N.M., Pinchuk, L.M., Boyd, B.L., and Crittenden, P.L. (2005). Immunotoxic effects of short-term atrazine exposure in young male C57Bl/6 mice. Toxicol. Sci. 86, 324-332.
    • (2005) Toxicol. Sci. , vol.86 , pp. 324-332
    • Filipov, N.M.1    Pinchuk, L.M.2    Boyd, B.L.3    Crittenden, P.L.4
  • 16
    • 33845510742 scopus 로고    scopus 로고
    • Atrazine increases ranavirus susceptibility in the tiger salamander, Ambystoma tigrinum
    • Forson, D.D., and Storfer, A. (2006). Atrazine increases ranavirus susceptibility in the tiger salamander, Ambystoma tigrinum. Ecol. Appl. 16, 2325-2332.
    • (2006) Ecol. Appl. , vol.16 , pp. 2325-2332
    • Forson, D.D.1    Storfer, A.2
  • 17
    • 8744223170 scopus 로고    scopus 로고
    • Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotox-icity tests
    • Genschow, E., Spielmann, H., Scholz, G., Pohl, I., Seiler, A., Clemann, N., Bremer, S., and Becker, K. (2004). Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotox-icity tests. Altern. Lab. Anim. 32, 209-244.
    • (2004) Altern. Lab. Anim. , vol.32 , pp. 209-244
    • Genschow, E.1    Spielmann, H.2    Scholz, G.3    Pohl, I.4    Seiler, A.5    Clemann, N.6    Bremer, S.7    Becker, K.8
  • 18
    • 75249104632 scopus 로고    scopus 로고
    • Ministère du Développement durable, de l'Environnement et des Parcs, Direction du suivi de l'état de l'environnement, Direction des politiques de l'eau, et Centre d'expertise en analyse environnementale du Québec, Québec, QC, Canada. ISBN 2-550-46504-0 Envirodoq n° ENV/2006/013, collection n° QE/00173, p 57 and 5 annexes
    • Giroux, I., Robert, C., and Dassylva, N. (2006). Présence de pesticides dans l'eau au Québec: bilan dans des cours d'eau de zones en culture de maïs et de soya en 2002, 2003 et 2004, et dans les réseaux de distribution d'eau potable. Ministère du Développement durable, de l'Environnement et des Parcs, Direction du suivi de l'état de l'environnement, Direction des politiques de l'eau, et Centre d'expertise en analyse environnementale du Québec, Québec, QC, Canada. ISBN 2-550-46504-0, Envirodoq n° ENV/2006/013, collection n° QE/00173, p. 57 and 5 annexes.
    • (2006) Présence de pesticides dans l'eau au Québec: bilan dans des cours d'eau de zones en culture de maïs et de soya en 2002, 2003 et 2004, et dans les réseaux de distribution d'eau potable
    • Giroux, I.1    Robert, C.2    Dassylva, N.3
  • 19
    • 29544442417 scopus 로고    scopus 로고
    • The endocrine disruptor atrazine accounts for a dimorphic somatostatinergic neuronal expression pattern in mice
    • Giusi, G., Facciolo, R.M., Canonaco, M., Alleva, E., Belloni, V., Dessi'-Fulgheri, F., and Santucci, D. (2006). The endocrine disruptor atrazine accounts for a dimorphic somatostatinergic neuronal expression pattern in mice. Toxicol. Sci. 89, 257-264.
    • (2006) Toxicol. Sci. , vol.89 , pp. 257-264
    • Giusi, G.1    Facciolo, R.M.2    Canonaco, M.3    Alleva, E.4    Belloni, V.5    Dessi'-Fulgheri, F.6    Santucci, D.7
  • 20
    • 0034913036 scopus 로고    scopus 로고
    • Impacts of atrazine in aquatic ecosystems
    • Graymore, M., Stagnitti, F., and Allinson, G. (2001). Impacts of atrazine in aquatic ecosystems. Environ. Int. 26, 483-495.
    • (2001) Environ. Int. , vol.26 , pp. 483-495
    • Graymore, M.1    Stagnitti, F.2    Allinson, G.3
  • 21
    • 2442620495 scopus 로고    scopus 로고
    • Low-dose agrochemicals and lawn-care pesticides induce developmental toxicity in murine preimplantation embryos
    • Greenlee, A.R., Ellis, T.M., and Berg, R.L. (2004). Low-dose agrochemicals and lawn-care pesticides induce developmental toxicity in murine preimplantation embryos. Environ. Health Perspect. 112, 703-709.
    • (2004) Environ. Health Perspect. , vol.112 , pp. 703-709
    • Greenlee, A.R.1    Ellis, T.M.2    Berg, R.L.3
  • 22
    • 18844450722 scopus 로고    scopus 로고
    • Ontogenic delays in effects of nitrite exposure on tiger salamanders (Ambystoma tigrinum tigrinum) and wood frogs (Rana sylvatica)
    • Griffis-Kyle, K.L. (2005). Ontogenic delays in effects of nitrite exposure on tiger salamanders (Ambystoma tigrinum tigrinum) and wood frogs (Rana sylvatica). Environ. Toxicol. Chem. 24, 1523-1527.
    • (2005) Environ. Toxicol. Chem. , vol.24 , pp. 1523-1527
    • Griffis-Kyle, K.L.1
  • 23
    • 0022387117 scopus 로고
    • Metabolism of retinoids by embryonal carcinoma cells
    • Gubler, M.L., and Sherman, M. (1985). Metabolism of retinoids by embryonal carcinoma cells. J. Biol. Chem. 17, 9552-9558.
    • (1985) J. Biol. Chem. , vol.17 , pp. 9552-9558
    • Gubler, M.L.1    Sherman, M.2
  • 24
    • 34948823851 scopus 로고    scopus 로고
    • Can nitrates lead to indirect toxicity?
    • Hamon, M. (2007). Can nitrates lead to indirect toxicity? Ann. Pharm. Fr. 65, 347-355.
    • (2007) Ann Pharm. Fr. , vol.65 , pp. 347-355
    • Hamon, M.1
  • 25
    • 0037117599 scopus 로고    scopus 로고
    • Hermaphroditic, demasculunized frogs after exposure to the herbicide atrazine at low ecologically relevant doses
    • Hayes, T.B., Collins, A., Lee, M., Mendoza, M., Noriega, N., Stuart, A.A., and Vonk, A. (2002). Hermaphroditic, demasculunized frogs after exposure to the herbicide atrazine at low ecologically relevant doses. Proc. Natl. Acad. Sci. U.S.A. 99, 5476-5480.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 5476-5480
    • Hayes, T.B.1    Collins, A.2    Lee, M.3    Mendoza, M.4    Noriega, N.5    Stuart, A.A.6    Vonk, A.7
  • 26
    • 0030724213 scopus 로고    scopus 로고
    • Convertase PC2 and the neuroendocrine polypeptide 7B2 are co-induced and processed during neuronal differentiation of P19 embryonal carcinoma cells
    • Jeannotte, R., Paquin, J., Petit-Turcotte, C., and Day, R. (1997). Convertase PC2 and the neuroendocrine polypeptide 7B2 are co-induced and processed during neuronal differentiation of P19 embryonal carcinoma cells. DNA Cell Biol. 16, 1175-1187.
    • (1997) DNA Cell Biol. , vol.16 , pp. 1175-1187
    • Jeannotte, R.1    Paquin, J.2    Petit-Turcotte, C.3    Day, R.4
  • 28
    • 0031821135 scopus 로고    scopus 로고
    • Effect of added drinking water nitrate on the vitamin A status of rabbits
    • Kammerer, M., and Pinault, L. (1998). Effect of added drinking water nitrate on the vitamin A status of rabbits. Vet. Hum. Toxicol. 40, 197-199.
    • (1998) Vet. Hum. Toxicol. , vol.40 , pp. 197-199
    • Kammerer, M.1    Pinault, L.2
  • 29
    • 0035513932 scopus 로고    scopus 로고
    • Effects and neuro-toxic mechanisms of 2, 2′, 4, 4′, 5 5′-hexachlorobiphenyl and endosulfan in neuronal stem cells
    • Kang, K.-S., Park, J.-E., Ryu, D.-Y., and Lee, Y.-S. (2001). Effects and neuro-toxic mechanisms of 2, 2′, 4, 4′, 5, 5′-hexachlorobiphenyl and endosulfan in neuronal stem cells. J. Vet. Med. Sci. 63, 1183-1190.
    • (2001) J. Vet. Med. Sci. , vol.63 , pp. 1183-1190
    • Kang, K.-S.1    Park, J.-E.2    Ryu, D.-Y.3    Lee, Y.-S.4
  • 30
    • 0029855241 scopus 로고    scopus 로고
    • Expression and posttranslational modification of class III beta-tubulin during neuronal differentiation of P19 embryonal carcinoma cells
    • Laferrière, N. B., and Brown, D.L. (1996). Expression and posttranslational modification of class III beta-tubulin during neuronal differentiation of P19 embryonal carcinoma cells. Cell Motil. Cytoskeleton 35, 188-199.
    • (1996) Cell Motil. Cytoskeleton , vol.35 , pp. 188-199
    • Laferrière, N.B.1    Brown, D.L.2
  • 31
    • 3543143089 scopus 로고    scopus 로고
    • RhoA/ROCK and Cdc42 regulate cell-cell contact and N-cadherin protein level during neurodetermination of P19 embryonal stem cells
    • Laplante, I., Béliveau, R., and Paquin, J. (2004). RhoA/ROCK and Cdc42 regulate cell-cell contact and N-cadherin protein level during neurodetermination of P19 embryonal stem cells. J. Neurobiol. 60, 289-307.
    • (2004) J. Neurobiol. , vol.60 , pp. 289-307
    • Laplante, I.1    Béliveau, R.2    Paquin, J.3
  • 32
    • 33750009766 scopus 로고    scopus 로고
    • Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line
    • Laville, N., Balaguer, P., Brion, F., Hinfray, N., Casellas, C., Porcher, J.M., and Aït-Aïssa, S. (2006). Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. Toxicology 228, 98-108.
    • (2006) Toxicology , vol.228 , pp. 98-108
    • Laville, N.1    Balaguer, P.2    Brion, F.3    Hinfray, N.4    Casellas, C.5    Porcher, J.M.6    Aït-Aïssa, S.7
  • 34
    • 34548503654 scopus 로고    scopus 로고
    • Combined exposure to ambient UVB radiation and nitrite negatively affects survival of amphibian early life stages
    • Macias, G., Marco, A., and Blaustein, A.R. (2007). Combined exposure to ambient UVB radiation and nitrite negatively affects survival of amphibian early life stages. Sci. Total Environ. 385, 55-65.
    • (2007) Sci. Total Environ. , vol.385 , pp. 55-65
    • Macias, G.1    Marco, A.2    Blaustein, A.R.3
  • 35
    • 0033012116 scopus 로고    scopus 로고
    • The effects of nitrite on behavior and metamorphosis in Cascades frogs (Rana cascadae)
    • Marco, A., and Blaustein, A.R. (1999). The effects of nitrite on behavior and metamorphosis in Cascades frogs (Rana cascadae). Environ. Toxicol. Chem. 18, 946-949.
    • (1999) Environ. Toxicol. Chem. , vol.18 , pp. 946-949
    • Marco, A.1    Blaustein, A.R.2
  • 36
    • 0027153542 scopus 로고
    • P19 embryonal carcinoma cells
    • McBurney, M.W. (1993). P19 embryonal carcinoma cells. Int. J. Dev. Biol. 7, 135-140.
    • (1993) Int. J. Dev. Biol. , vol.7 , pp. 135-140
    • McBurney, M.W.1
  • 37
    • 51249181330 scopus 로고
    • Oxidation and isomerisation of retinoid acid by iodine and light: An ovel preparation of all-trans- and 13-cis-4-oxoretinoic acid
    • McKenzie, R.M., Hellwege, D.M., McGregor, M.L., and Nelson, E.C. (1979). Oxidation and isomerisation of retinoid acid by iodine and light: An ovel preparation of all-trans- and 13-cis-4-oxoretinoic acid. Lipids 14, 714-717.
    • (1979) Lipids , vol.14 , pp. 714-717
    • McKenzie, R.M.1    Hellwege, D.M.2    McGregor, M.L.3    Nelson, E.C.4
  • 39
    • 48549093762 scopus 로고    scopus 로고
    • Disruption of retinoid transport, metabolism and signalling by environmental pollutants
    • Novák, J., Benísek M., and Hilscherová, K. (2008). Disruption of retinoid transport, metabolism and signalling by environmental pollutants. Environ. Int. 34, 989-1913.
    • (2008) Environ. Int. , vol.34 , pp. 989-1913
    • Novák, J.1    Benísek, M.2    Hilscherová, K.3
  • 40
    • 0032911542 scopus 로고    scopus 로고
    • Concise review of the cytochrome P450s and their roles in toxicology
    • Omiecinski, C.J., Remmel, R.P., and Hosagrahara, V.P. (1999). Concise review of the cytochrome P450s and their roles in toxicology. Toxicol. Sci. 48, 151-156.
    • (1999) Toxicol. Sci. , vol.48 , pp. 151-156
    • Omiecinski, C.J.1    Remmel, R.P.2    Hosagrahara, V.P.3
  • 41
    • 3242668849 scopus 로고    scopus 로고
    • Impact of ammonium nitrate on growth and survival of six European amphibians
    • Ortiz, M.E., Marco, A., Saiz, N., and Lizana, M. (2004). Impact of ammonium nitrate on growth and survival of six European amphibians. Arch. Environ. Contam. Toxicol. 47, 234-239.
    • (2004) Arch. Environ. Contam. Toxicol. , vol.47 , pp. 234-239
    • Ortiz, M.E.1    Marco, A.2    Saiz, N.3    Lizana, M.4
  • 42
    • 29744446626 scopus 로고    scopus 로고
    • Effects of nitrate and atrazine on larval development and sexual differentiation in the northern leopard frog Rana pipiens
    • Orton, F., Carr, J.A., and Handy, R.D. (2006). Effects of nitrate and atrazine on larval development and sexual differentiation in the northern leopard frog Rana pipiens. Environ. Toxicol. Chem. 25, 65-71.
    • (2006) Environ. Toxicol. Chem. , vol.25 , pp. 65-71
    • Orton, F.1    Carr, J.A.2    Handy, R.D.3
  • 43
    • 0030638287 scopus 로고    scopus 로고
    • Hindlimb deformities (ectromelia, ectrodactyly) in free-living anurans from agricultural habitats
    • Ouellet, M., Bonin, J., Rodrigue, J., DesGranges, J.L., and Lair, S. (1997). Hindlimb deformities (ectromelia, ectrodactyly) in free-living anurans from agricultural habitats. J. Wild. Dis. 33, 95-104.
    • (1997) J. Wild. Dis. , vol.33 , pp. 95-104
    • Ouellet, M.1    Bonin, J.2    Rodrigue, J.3    DesGranges, J.L.4    Lair, S.5
  • 44
    • 14944372538 scopus 로고    scopus 로고
    • Neural differentiation of pluripotent mouse embryonal carcinoma cells by retinoic acid: Inhibitory effect of serum
    • Pachernik, J., Bryja, V., Esner, M., Kubala, L., Dvorak, P., and Hampl, A. (2005). Neural differentiation of pluripotent mouse embryonal carcinoma cells by retinoic acid: Inhibitory effect of serum. Physiol. Res. 54, 115-122.
    • (2005) Physiol. Res. , vol.54 , pp. 115-122
    • Pachernik, J.1    Bryja, V.2    Esner, M.3    Kubala, L.4    Dvorak, P.5    Hampl, A.6
  • 47
    • 0028018251 scopus 로고
    • Effects of retinoic acid metabolites on proliferation and differentiation of the clonal rhabdomyosarcoma cell line BA-HAN-1C
    • Ramp, U., Gerharz, C.D., Eifler, E., Bielsalski, H.K., and Gabbert, H.E. (1994). Effects of retinoic acid metabolites on proliferation and differentiation of the clonal rhabdomyosarcoma cell line BA-HAN-1C. Biol. Cell 81, 31-37.
    • (1994) Biol. Cell. , vol.81 , pp. 31-37
    • Ramp, U.1    Gerharz, C.D.2    Eifler, E.3    Bielsalski, H.K.4    Gabbert, H.E.5
  • 48
    • 0034924237 scopus 로고    scopus 로고
    • F9 embryocarcinoma cells: A cell autonomous model to study the functional selectivity of RARs and RXRs in retinoid signalling
    • Rochette-Egly, C., and Chambon, P. (2001). F9 embryocarcinoma cells: A cell autonomous model to study the functional selectivity of RARs and RXRs in retinoid signalling. Histol. Histopathol. 16, 909-922.
    • (2001) Histol. Histopathol. , vol.16 , pp. 909-922
    • Rochette-Egly, C.1    Chambon, P.2
  • 49
    • 20844450586 scopus 로고    scopus 로고
    • Sustained exposure to the widely used herbicide atrazine: Altered function and loss of neurons in brain monoamine systems
    • Rodriguez, V.M., Thiruchelvam, M., and Cory-Slechta, D.A. (2005). Sustained exposure to the widely used herbicide atrazine: Altered function and loss of neurons in brain monoamine systems. Environ. Health Perspect. 113, 708-715.
    • (2005) Environ. Health Perspect. , vol.113 , pp. 708-715
    • Rodriguez, V.M.1    Thiruchelvam, M.2    Cory-Slechta, D.A.3
  • 50
    • 1842715885 scopus 로고    scopus 로고
    • Embryonic stem cell-derived cardiac, neuronal an pancreatic cells as model systems to study toxicological effects
    • Rolletschek, A., Blyszcuk, P., and Wobus, A.M. (2004). Embryonic stem cell-derived cardiac, neuronal an pancreatic cells as model systems to study toxicological effects. Toxicol. Lett. 149, 361-369.
    • (2004) Toxicol. Lett. , vol.149 , pp. 361-369
    • Rolletschek, A.1    Blyszcuk, P.2    Wobus, A.M.3
  • 51
    • 0032694760 scopus 로고    scopus 로고
    • Nitrogen pollution: An assessment of its threat to amphibian survival
    • Rouse, J.D., Bishop, C.A., and Struger, J. (1999). Nitrogen pollution: An assessment of its threat to amphibian survival. Environ. Health Perspect. 107, 799-803.
    • (1999) Environ. Health Perspect. , vol.107 , pp. 799-803
    • Rouse, J.D.1    Bishop, C.A.2    Struger, J.3
  • 52
    • 0032524688 scopus 로고    scopus 로고
    • Evaluation of P19 cells for studying mechanisms of developmental toxicity: Applications to four directacting alkylating agents
    • Seeley, M.R., and Faustman, E.M. (1998). Evaluation of P19 cells for studying mechanisms of developmental toxicity: Applications to four directacting alkylating agents. Toxicology 127, 49-58.
    • (1998) Toxicology , vol.127 , pp. 49-58
    • Seeley, M.R.1    Faustman, E.M.2
  • 53
    • 0023269161 scopus 로고
    • The role of aggregation in embryonal carcinoma cell differentiation
    • Smith, S.C., Reuhl, K.R., Craig, J., and McBurney, M.W. (1987). The role of aggregation in embryonal carcinoma cell differentiation. J. Cell Physiol. 131, 74-84.
    • (1987) J. Cell Physiol. , vol.131 , pp. 74-84
    • Smith, S.C.1    Reuhl, K.R.2    Craig, J.3    McBurney, M.W.4
  • 54
    • 0033568004 scopus 로고    scopus 로고
    • Retinoic acid hydroxylase (CYP26) is a key enzyme in neuronal differentiation of embryonal carcinoma cells
    • Sonneveld, E., van den Brink, C.E., Tertoolen, L.G.J., van der Burg, B., and van der Saag, P.T. (1999). Retinoic acid hydroxylase (CYP26) is a key enzyme in neuronal differentiation of embryonal carcinoma cells. Dev. Biol. 213, 390-404.
    • (1999) Dev. Biol. , vol.213 , pp. 390-404
    • Sonneveld, E.1    van den Brink, C.E.2    Tertoolen, L.G.J.3    van der Burg, B.4    van der Saag, P.T.5
  • 55
    • 58149517974 scopus 로고    scopus 로고
    • Study design, water quality, morphometrics and age of the bullfrog, Rana catesbeiana, in sub-watersheds of the Yamaska River drainage basin, Quebec
    • (special issue Amphib. Toxicol.)
    • Spear, P.A., Boily, M., Giroux, I., DeBlois, C., Leclair, M.H., Levasseur, M., and Leclair, R. (2009). Study design, water quality, morphometrics and age of the bullfrog, Rana catesbeiana, in sub-watersheds of the Yamaska River drainage basin, Quebec, Canada. Aquat. Toxicol. (special issue Amphib. Toxicol.) 91, 110-117.
    • (2009) Canada. Aquat. Toxicol. , vol.91 , pp. 110-117
    • Spear, P.A.1    Boily, M.2    Giroux, I.3    DeBlois, C.4    Leclair, M.H.5    Levasseur, M.6    Leclair, R.7
  • 56
    • 0037369323 scopus 로고    scopus 로고
    • Effects of sublethal concentrations of atrazine and nitrate on metamorphosis of the African clawed frog
    • Sullivan, K.B., and Spence, K.M. (2003). Effects of sublethal concentrations of atrazine and nitrate on metamorphosis of the African clawed frog. Environ. Toxicol. Chem. 22, 627-635.
    • (2003) Environ. Toxicol. Chem. , vol.22 , pp. 627-635
    • Sullivan, K.B.1    Spence, K.M.2
  • 57
    • 0036188644 scopus 로고    scopus 로고
    • Response of the amphibian tadpole (Xenopus laevis) to atrazine during sexual differentiation of the testis
    • Tavera-Mendoza, L., Ruby, S., Brousseau, P., Fournier, M., Cyr, D., and Marcogliese, D. (2002). Response of the amphibian tadpole (Xenopus laevis) to atrazine during sexual differentiation of the testis. Environ. Toxicol. Chem. 21, 527-531.
    • (2002) Environ. Toxicol. Chem. , vol.21 , pp. 527-531
    • Tavera-Mendoza, L.1    Ruby, S.2    Brousseau, P.3    Fournier, M.4    Cyr, D.5    Marcogliese, D.6
  • 58
    • 0034807553 scopus 로고    scopus 로고
    • Atrazine potentiation of arsenic trioxide-induces cytotoxicity and gene expression in human liver arcinoma cells (HepG2)
    • Tchounwou, P.B., Wilson, B.A., Ishaque, A.B., and Schneider, J. (2001). Atrazine potentiation of arsenic trioxide-induces cytotoxicity and gene expression in human liver arcinoma cells (HepG2). Mol. Cell Biochem. 222, 49-59.
    • (2001) Mol. Cell Biochem. , vol.222 , pp. 49-59
    • Tchounwou, P.B.1    Wilson, B.A.2    Ishaque, A.B.3    Schneider, J.4
  • 59
    • 33846147970 scopus 로고    scopus 로고
    • Relating olfactory neurotoxicity to altered olfactory-mediated behaviors in rainbow trout exposed to three currently-used pesticides
    • Tierney, K.B., Singh, C.R., Ross, P.S., and Kennedy, C.J. (2007). Relating olfactory neurotoxicity to altered olfactory-mediated behaviors in rainbow trout exposed to three currently-used pesticides. Aquat. Toxicol. 81, 55-64.
    • (2007) Aquat. Toxicol. , vol.81 , pp. 55-64
    • Tierney, K.B.1    Singh, C.R.2    Ross, P.S.3    Kennedy, C.J.4
  • 60
    • 0023212895 scopus 로고
    • Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells
    • Williams, J.B., and Napoli, J.L. (1987). Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells. Biochem. Pharmacol. 36, 1386-1388.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 1386-1388
    • Williams, J.B.1    Napoli, J.L.2
  • 61
    • 28844438444 scopus 로고    scopus 로고
    • Characterization of glycoconjugate antigens in mouse embryonic neural precursor cells
    • Yanagisawa, M., Taga, T., Nakamura, K., Ariga, T., and Yu, R.K. (2005). Characterization of glycoconjugate antigens in mouse embryonic neural precursor cells. J. Neurochem. 95, 1311-1320.
    • (2005) J. Neurochem. , vol.95 , pp. 1311-1320
    • Yanagisawa, M.1    Taga, T.2    Nakamura, K.3    Ariga, T.4    Yu, R.K.5
  • 62
    • 0026699306 scopus 로고
    • Vitamin A homeostasis endangered by environmental pollutants
    • Zile, M.H. (1992). Vitamin A homeostasis endangered by environmental pollutants. Proc. Soc. Exp. Biol. Med. 201, 141-153.
    • (1992) Proc. Soc. Exp. Biol. Med. , vol.201 , pp. 141-153
    • Zile, M.H.1
  • 63
    • 0035095989 scopus 로고    scopus 로고
    • Function of vitamin A in vertebrate embryonic development
    • Zile, M.H. (2001). Function of vitamin A in vertebrate embryonic development. J. Nutr. 131, 705-708.
    • (2001) J. Nutr. , vol.131 , pp. 705-708
    • Zile, M.H.1


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