Type 2 immune-inducing helminth vaccination maintains protective efficacy in the setting of repeated parasite exposures

Vaccine

Volumn 28, Issue 7, 2010, Pages 1746-1757

  Hübner, Marc P ^a   Torrero, Marina N ^a   Mitre, Edward ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Basophil; Desensitization; Filaria; Helminth; IgE; IL 4; Immunological tolerance; Litomosoides sigmodontis; Regulatory T cells; Type 2 immunity; Vaccine

Indexed keywords

IMMUNOGLOBULIN E; INTERLEUKIN 10; INTERLEUKIN 4; LITOMOSOIDES SIGMODONTIS ANTIGEN; PARASITE ANTIGEN; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL COUNT; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; FEMALE; FILARIASIS; HELMINTH; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IRRADIATION; LITOMOSOIDES SIGMODONTIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH2 CELL; VACCINATION;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; CELL PROLIFERATION; FEMALE; FILARIASIS; FILARIOIDEA; IMMUNOGLOBULIN E; INTERLEUKIN-10; INTERLEUKIN-4; LARVA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SPLEEN; T-LYMPHOCYTES, REGULATORY; TH2 CELLS; VACCINES;

EID: 75249106184     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.12.016     Document Type: Article

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