Progesterone decreases tyrosine hydroxylase phosphorylation state and increases protein phosphatase 2A activity in the stalk-median eminence on proestrous afternoon

Journal of Endocrinology

Volumn 204, Issue 2, 2010, Pages 209-219

  Liu, Bin ^a   Arbogast, Lydia A ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; PHOSPHOPROTEIN PHOSPHATASE 2A; PROGESTERONE; PROLACTIN; TYROSINE 3 MONOOXYGENASE;

ARTICLE; DRUG MECHANISM; ENZYME ACTIVITY; FEMALE; MEDIAN EMINENCE; NONHUMAN; PRIORITY JOURNAL; PROESTRUS; PROLACTIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; TUBEROHYPOPHYSEAL TRACT;

ANIMALS; CIRCADIAN RHYTHM; CYCLIC AMP; ESTROUS CYCLE; FEMALE; MEDIAN EMINENCE; NEURONS; OVARIECTOMY; PHOSPHORYLATION; PROGESTERONE; PROLACTIN; PROTEIN PHOSPHATASE 2; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE 3-MONOOXYGENASE;

EID: 75149186209     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-09-0335     Document Type: Article

References (55)

1. Arbogast LA & Ben-Jonathan N 1989 Tyrosine hydroxylase in the stalk-median eminence and posterior pituitary is inactivated only during the plateau phase of the preovulatory prolactin surge. Endocrinology 125 667-674.
2. Arbogast LA & Ben-Jonathan N 1990 The preovulatory prolactin surge is prolonged by a progesterone-dependent dopaminergic mechanism. Endocrinology 126 246-252.
3. Arbogast LA & Voogt JL 1991 Hyperprolactinemia increases and hypoprolactinemia decreases tyrosine hydroxylase messenger ribonucleic acid levels in the arcuate nuclei, but not the substantia nigra or zona incerta. Endocrinology 128 997-1005.
4. Arbogast LA & Voogt JL 1994 Progesterone suppresses tyrosine hydroxylase messenger ribonucleic acid levels in the arcuate nucleus on proestrus. Endocrinology 135 343-350.
5. Arbogast LA & Voogt JL 2002 Progesterone induces dephosphorylation and inactivation of tyrosine hydroxylase in rat hypothalamic dopaminergic neurons. Neuroendocrinology 75 273-281.
6. Babu GN & Vijayan E 1984 Hypothalamic tyrosine hydroxylase activity and plasma gonadotropin and prolactin levels in ovariectomized-steroid treated rats. Brain Research Bulletin 12 555-558.
7. Beattie CW, Rodgers CH & Soyka LF 1972 Influence of ovariectomy and ovarian steroids on hypothalamic tyrosine hydroxylase activity in the rat. Endocrinology 91 276-279.
8. Ben-Jonathan N & Hnasko R 2001 Dopamine as a prolactin (PRL) inhibitor. Endocrine Reviews 22 724-763.
9. Berresheim U & Kuhn DM 1994 Dephosphorylation of tyrosine hydroxylase by brain protein phosphatases: a predominant role for type 2A. Brain Research 637 273-276.
10. Bevilaqua LR, Graham ME, Dunkley PR, von Nagy-Felsobuki EI & Dickson PW 2001 Phosphorylation of Ser(19) alters the conformation of tyrosine hydroxylase to increase the rate of phosphorylation of Ser(40). Journal of Biological Chemistry 276 40411-40416.
11. Bevilaqua LR, Cammarota M, Dickson PW, Sim AT & Dunkley PR 2003 Role of protein phosphatase 2C from bovine adrenal chromaffin cells in the dephosphorylation of phospho-serine 40 tyrosine hydroxylase. Journal of Neurochemistry 85 1368-1373.
12. Bobrovskaya L, Dunkley PR & Dickson PW 2004 Phosphorylation of Ser19 increases both Ser40 phosphorylation and enzyme activity of tyrosine hydroxylase in intact cells. Journal of Neurochemistry 90 857-864.
13. Brandi AM, Joannidis S, Peillon F & Joubert D 1990 Changes of prolactin response to dopamine during the rat estrous cycle. Neuroendocrinology 51 449-454.
14. Bression D, Brandi AM, Pagesy P, Le Dafniet M, Martinet M, Brailly S, Michard M & Peillon F 1985 In vitro and in vivo antagonistic regulation by estradiol and progesterone of the rat pituitary domperidone binding sites: correlation with ovarian steroid regulation of the dopaminergic inhibition of prolactin secretion in vitro. Endocrinology 116 1905-1911.
15. Caligaris L, Astrada JJ & Taleisnik S 1974 Oestrogen and progesterone influence on the release of prolactin in ovariectomized rats. Journal of Endocrinology 60 205-215.
16. Daubner SC, Lauriano C, Haycock JW & Fitzpatrick PF 1992 Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity. Journal of Biological Chemistry 267 12639-12646.
17. Dobrowsky RT, Kamibayashi C, Mumby MC & Hannun YA 1993 Ceramide activates heterotrimeric protein phosphatase 2A. Journal of Biological Chemistry 268 15523-15530.
18. Dunkley PR, Bobrovskaya L, Graham ME, von Nagy-Felsobuki EI & Dickson PW 2004 Tyrosine hydroxylase phosphorylation: regulation and consequences. Journal of Neurochemistry 91 1025-1043.
19. Fox SR, Harlan RE, Shivers BD & Pfaff DW1990 Chemical characterization of neuroendocrine targets for progesterone in the female rat brain and pituitary. Neuroendocrinology 51 276-283.
20. Freeman ME, Kanyicska B, Lerant A & Nagy G 2000 Prolactin: structure, function, and regulation of secretion. Physiological Reviews 80 1523-1631.
21. Gaytan F, Bellido C, Morales C & Sanchez-Criado JE 2001 Cyclic changes in the responsiveness of regressing corpora lutea to the luteolytic effects of prolactin in rats. Reproduction 122 411-417.
22. Goldstein M 2000 Long- and short-term regulation of tyrosine hydroxylase. In Psychopharmacology, pp 1-6. Ed. JH Meador-Woodruff. www.acnp.org. The American College of Psychoneuropharmacology.
23. Gonzalez HA, KedzierskiW, Aguila-Mansilla N & Porter JC 1989 Hormonal control of tyrosine hydroxylase in the median eminence: demonstration of a central role for the pituitary gland. Endocrinology 124 2122-2127.
24. Haavik J, Schelling DL, Campbell DG, Andersson KK, Flatmark T & Cohen P 1989 Identification of protein phosphatase 2A as the major tyrosine hydroxylase phosphatase in adrenal medulla and corpus striatum: evidence from the effects of okadaic acid. FEBS Letters 251 36-42.
25. Haycock JW 1990 Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40. Journal of Biological Chemistry 265 11682-11691.
26. Haycock JW & Haycock DA 1991 Tyrosine hydroxylase in rat brain dopaminergic nerve terminals. Multiple-site phosphorylation in vivo and in synaptosomes. Journal of Biological Chemistry 266 5650-5657.
27. Haycock JW, Ahn NG, Cobb MH & Krebs EG 1992 ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. PNAS 89 2365-2369.
28. Haycock JW, Lew JY, Garcia-Espana A, Lee KY, Harada K, Meller E & GoldsteinM1998 Role of serine-19 phosphorylation in regulating tyrosine hydroxylase studied with site- and phosphospecific antibodies and sitedirected mutagenesis. Journal of Neurochemistry 71 1670-1675.
29. Heiman ML & Ben-Jonathan N 1982 Dopaminergic receptors in the rat anterior pituitary change during the estrous cycle. Endocrinology 111 37-41.
30. Kamibayashi C, Estes R, Lickteig RL, Yang SI, Craft C & Mumby MC 1994 Comparison of heterotrimeric protein phosphatase 2A containing different B subunits. Journal of Biological Chemistry 269 20139-20148.
31. Kansy JW, Daubner SC, Nishi A, Sotogaku N, Lloyd MD, Nguyen C, Lu L, Haycock JW, Hope BT, Fitzpatrick PF et al. 2004 Identification of tyrosine hydroxylase as a physiological substrate for Cdk5. Journal of Neurochemistry 91 374-384.
32. Kennett JE, Poletini MO, Fitch CA & Freeman ME 2009 Antagonism of oxytocin prevents suckling- and estradiol-induced, but not progesteroneinduced, secretion of prolactin. Endocrinology 150 2292-2299.
33. Kraus WL, Montano MM & Katzenellenbogen BS 1994 Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene. Molecular Endocrinology 8 952-969.
34. Leal RB, Sim AT, Goncalves CA & Dunkley PR 2002 Tyrosine hydroxylase dephosphorylation by protein phosphatase 2A in bovine adrenal chromaffin cells. Neurochemical Research 27 207-213.
35. Lerant A & Freeman ME 1997 Dopaminergic neurons in periventricular and arcuate nuclei of proestrous and ovariectomized rats: endogenous diurnal rhythm of Fos-related antigens expression. Neuroendocrinology 65 436-445.
36. Liu B & Arbogast LA 2008 Phosphorylation state of tyrosine hydroxylase in the stalk-median eminence is decreased by progesterone in cycling female rats. Endocrinology 149 1462-1469.
37. Liu B & Arbogast LA 2009 Gene expression profiles of intracellular and membrane progesterone receptor isoforms in the mediobasal hypothalamus during pro-estrus. Journal of Neuroendocrinology 21 993-1000.
38. Lonstein JS & Blaustein JD 2004 Immunocytochemical investigation of nuclear progestin receptor expression within dopaminergic neurones of the female rat brain. Journal of Neuroendocrinology 16 534-543.
39. Mai LM, Shieh KR & Pan JT 1994 Circadian changes of serum prolactin levels and tuberoinfundibular dopaminergic neuron activities in ovariectomized rats treated with or without estrogen: the role of the suprachiasmatic nuclei. Neuroendocrinology 60 520-526.
40. Mani SK 2006 Signaling mechanisms in progesterone-neurotransmitter interactions. Neuroscience 138 773-781.
41. Morrell JI, Rosenthal MF, McCabe JT, Harrington CA, Chikaraishi DM & Pfaff DW 1989 Tyrosine hydroxylase mRNA in the neurons of the tuberoinfundibular region and zona incerta examined after gonadal steroid hormone treatment. Molecular Endocrinology 3 1426-1433.
42. Murai I, Reichlin S & Ben-Jonathan N 1989 The peak phase of the proestrous prolactin surge is blocked by either posterior pituitary lobectomy or antisera to vasoactive intestinal peptide. Endocrinology 124 1050-1055.
43. Neill JD, Freeman ME & Tillson SA 1971 Control of the proestrus surge of prolactin and luteinizing hormone secretion by estrogens in the rat. Endocrinology 89 1448-1453.
44. Pasqualini C, Lenoir V, Abed A & Kerdelhué B 1984 Anterior pituitary dopamine receptors during the rat estrous cycle. A detailed analysis of proestrus changes. Neuroendocrinology 38 39-44.
45. Pasqualini C, Bojda F & Kerdelhué B 1986 Direct effect of estradiol on the number of dopamine receptors in the anterior pituitary of ovariectomized rats. Endocrinology 119 2484-2489.
46. Samson WK, Lumpkin MD & McCann SM 1986 Evidence for a physiological role of oxytocin in the control of prolactin secretion. Endocrinology 119 554-560.
47. Sar M 1988 Distribution of progestin-concentrating cells in rat brain: colocalization of [3H]ORG.2058, a synthetic progestin, and antibodies to tyrosine hydroxylase in hypothalamus by combined autoradiography and immunocytochemistry. Endocrinology 123 1110-1118.
48. Scott RE, Wu-Peng XS & Pfaff DW 2002 Regulation and expression of progesterone receptor mRNA isoforms A and B in the male and female rat hypothalamus and pituitary following oestrogen treatment. Journal of Neuroendocrinology 14 175-183.
49. Shieh KR & Pan JT 1996 Sexual differences in the diurnal changes of tuberoinfundibular dopaminergic neuron activity in the rat: role of cholinergic control. Biology of Reproduction 54 987-992.
50. Shughrue PJ, Lane MV & Merchenthaler I 1997 Regulation of progesterone receptor messenger ribonucleic acid in the rat medial preoptic nucleus by estrogenic and antiestrogenic compounds: an in situ hybridization study. Endocrinology 138 5476-5484.
51. Smith MS, Freeman ME & Neill JD 1975 The control of progesterone secretion during the estrous cycle and early pseudopregnancy in the rat: prolactin, gonadotropin and steroid levels associated with rescue of the corpus luteum of pseudopregnancy. Endocrinology 96 219-226.
52. Thomas P 2008 Characteristics of membrane progestin receptor alpha (mPRalpha) and progesterone membrane receptor component 1 (PGMRC1) and their roles in mediating rapid progestin actions. Frontiers in Neuroendocrinology 29 292-312.
53. Toska K, Kleppe R, Armstrong CG, Morrice NA, Cohen P & Haavik J 2002 Regulation of tyrosine hydroxylase by stress-activated protein kinases. Journal of Neurochemistry 83 775-783.
54. Wang PS & Porter JC 1986 Hormonal modulation of the quantity and in situ activity of tyrosine hydroxylase in neurites of the median eminence. PNAS 83 9804-9806.
55. Yen SH & Pan JT 1998 Progesterone advances the diurnal rhythm of tuberoinfundibular dopaminergic neuronal activity and the prolactin surge in ovariectomized, estrogen-primed rats and in intact proestrous rats. Endocrinology 139 1602-1609.