Expression of genes related to oxidative/nitrosative stress in mouse hearts: Effect of preconditioning and cholesterol diet

Medical Science Monitor

Volumn 16, Issue 1, 2010, Pages

  Kocsis, Gabriella F ^a   Csont, Tamás ^a,b   Varga Orvos, Zoltán ^c   Puskás, László G ^c   Murlasits, Zsolt ^a,b   Ferdinandy, Péter ^a,b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b PHARMAHUNGARY GROUP   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Cardioprotection; Hypercholesterolemia; Ischemia reperfusion; Preconditioning

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; FREE RADICAL; NEURONAL NITRIC OXIDE SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; XANTHINE OXIDASE;

ANIMAL TISSUE; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; GENE EXPRESSION; HEART; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART PROTECTION; ISOLATED HEART; MALE; MOUSE; NITROSATIVE STRESS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS;

ANALYSIS OF VARIANCE; ANIMALS; CHOLESTEROL, DIETARY; DNA PRIMERS; GENE EXPRESSION REGULATION; HEART; HYPERCHOLESTEROLEMIA; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MEVALONIC ACID; MICE; MYOCARDIUM; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; XANTHINE OXIDASE;

EID: 75149180459     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Ferdinandy P, Schulz R, Baxter GF: Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning. Pharmacol Rev, 2007; 59: 418-58
2. Kanoni S, Dedoussis GV: Design and descriptive characteristics of the GHRAS: the Greek Health Randomized Aging Study. Med Sci Monit, 2008; 14(4): CR204-12
3. Ferdinandy P, Szilvassy Z, Baxter GF: Adaptation to myocardial stress in disease states: is preconditioning a healthy heart phenomenon? Trends Pharmacol Sci, 1998; 19: 223-29
4. Ungi I, Ungi T, Ruzsa Z et al: Hypercholesterolemia attenuates the anti-ischemic effect of preconditioning during coronary angioplasty. Chest, 2005; 128: 1623-28
5. Bolli R: Preconditioning: a paradigm shift in the biology of myocardial ischemia. Am J Physiol Heart Circ Physiol, 2007; 292: H19-27
6. Ferdinandy P, Szilvassy Z, Horvath LI et al: Loss of pacing-induced pre-conditioning in rat hearts: role of nitric oxide and cholesterol-enriched diet. J Mol Cell Cardiol, 1997; 29: 3321-33
7. Giricz Z, Lalu MM, Csonka C et al: Hyperlipidemia attenuates the infarct size-limiting effect of ischemic preconditioning: role of matrix metalloproteinase-2 inhibition. J Pharmacol Exp Ther, 2006; 316: 154-61
8. Iliodromitis EK, Zoga A, Vrettou A et al: The effectiveness of postconditioning and preconditioning on infarct size in hypercholesterolemic and normal anesthetized rabbits. Atherosclerosis, 2006; 188: 356-62
9. Szilvassy Z, Ferdinandy P, Szilvassy J et al: The loss of pacing-induced preconditioning in atherosclerotic rabbits: role of hypercholesterolaemia. J Mol Cell Cardiol, 1995; 27: 2559-69
10. Tang XL, Stein AB, Shirk G, Bolli R: Hypercholesterolemia blunts NO donor-induced late preconditioning against myocardial infarction in conscious rabbits. Basic Res Cardiol, 2004; 99: 395-403
11. Onody A, Csonka C, Giricz Z, Ferdinandy P: Hyperlipidemia induced by a cholesterol-rich diet leads to enhanced peroxynitrite formation in rat hearts. Cardiovasc Res, 2003; 58: 663-70
12. Csont T, Bereczki E, Bencsik P et al: Hypercholesterolemia increases myocardial oxidative and nitrosative stress thereby leading to cardiac dysfunction in apoB-100 transgenic mice. Cardiovasc Res, 2007; 76: 100-9
13. Ferdinandy P: Myocardial ischaemia/reperfusion injury and preconditioning: effects of hypercholesterolaemia/hyperlipidaemia. Br J Pharmacol, 2003; 138: 283-85
14. Ferdinandy P, Csonka C, Csont T et al: Rapid pacing-induced preconditioning is recaptured by farnesol treatment in hearts of cholesterol-fed rats: role of polyprenyl derivatives and nitric oxide. Mol Cell Biochem, 1998; 186: 27-34
15. Csonka C, Csont T, Onody A, Ferdinandy P: Preconditioning decreases ischemia/reperfusion-induced peroxynitrite formation. Biochem Biophys Res Commun, 2001; 285: 1217-19
16. Ferdinandy P, Schulz R: Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning. Br J Pharmacol, 2003; 138: 532-43
17. Martinet W, Schrijvers DM, De Meyer GR et al: Gene expression profiling of apoptosis-related genes in human atherosclerosis: upregulation of death-associated protein kinase. Arterioscler Thromb Vasc Biol, 2002; 22: 2023-29
18. Woodside KJ, Hernandez A, Smith FW et al: Differential gene expression in primary and recurrent carotid stenosis. Biochem Biophys Res Commun, 2003; 302: 509-14
19. Onody A, Zvara A, Hackler L et al: Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study. FEBS Lett, 2003; 536: 35-40
20. Puskas LG, Nagy ZB, Giricz Z et al: Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study. FEBS Lett, 2004; 562: 99-104
21. Csont T, Balogh G, Csonka C et al: Hyperlipidemia induced by high cholesterol diet inhibits heat shock response in rat hearts. Biochem Biophys Res Commun, 2002; 290: 1535-38
22. Csont T, Viappiani S, Sawicka J, Slee S et al: The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines. J Mol Cell Cardiol, 2005; 39: 833-40
23. Csonka C, Szilvassy Z, Fulop F et al: Classic preconditioning decreases the harmful accumulation of nitric oxide during ischemia and reperfusion in rat hearts. Circulation, 1999; 100: 2260-66
24. Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res, 2001; 29: e45
25. Girod WG, Jones SP, Sieber N et al: Effects of hypercholesterolemia on myocardial ischemia-reperfusion injury in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol, 1999; 19: 2776-81
26. Tang XL, Takano H, Xuan YT et al: Hypercholesterolemia abrogates late preconditioning via a tetrahydrobiopterin-dependent mechanism in conscious rabbits. Circulation, 2005; 112: 2149-56
27. Wang TD, Chen WJ, Su SS et al: Increased cardiomyocyte apoptosis following ischemia and reperfusion in diet-induced hypercholesterolemia: relation to Bcl-2 and Bax proteins and caspase-3 activity. Lipids, 2002; 37: 385-94
28. Guo Y, Li Q, Wu WJ et al: Endothelial nitric oxide synthase is not necessary for the early phase of ischemic preconditioning in the mouse. J Mol Cell Cardiol, 2008; 44: 496-501
29. Giricz Z, Csonka C, Onody A et al: Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis. Basic Res Cardiol, 2003; 98: 304-10
30. Fert-Bober J, Basran RS, Sawicka J et al: Effect of duration of ischemia on myocardial proteome in ischemia/reperfusion injury. Proteomics, 2008; 8: 2543-55
31. Pryor WA, Houk KN, Foote CS et al: Free radical biology and medicine: it's a gas, man! Am J Physiol Regul Integr Comp Physiol, 2006; 291: R491-511
32. Das DK, Maulik N: Cardiac genomic response following preconditioning stimulus. Cardiovasc Res, 2006; 70: 254-63
33. Jones SP, Hoffmeyer MR, Sharp BR et al: Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion. Am J Physiol Heart Circ Physiol, 2003; 284: H277-82
34. Nilakantan V, Zhou X, Hilton G et al: Hierarchical change in antioxidant enzyme gene expression and activity in acute cardiac rejection: role of inducible nitric oxide synthase. Mol Cell Biochem, 2005; 270: 39-47
35. Ness GC, Keller RK, Pendleton LC: Feedback regulation of hepatic 3-hydroxy-3-methylglutaryl-CoA reductase activity by dietary cholesterol is not due to altered mRNA levels. J Biol Chem, 1991; 266: 14854-57