Hyperlipidemia induced by high cholesterol diet inhibits heat shock response in rat hearts

Biochemical and Biophysical Research Communications

Volumn 290, Issue 5, 2002, Pages 1535-1538

  Csont, Tamás ^a   Csonka, Csaba ^a   Ferdinandy, Péter ^a   Balogh, Gábor ^b   Boros, Imre ^b   Horváth, Ibolya ^b   Vigh, László ^b  

^a UNIVERSITY OF SZEGED   (Hungary)

^b INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

Cholesterol diet; Heart; Heat stress; HSP70; Hypercholesterolemia; Hyperlipidemia; Ischemia

Indexed keywords

HEAT SHOCK PROTEIN 70; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; HEART; HEAT STRESS; HYPERLIPIDEMIA; ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

RATTUS NORVEGICUS;

EID: 0036297625     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6377     Document Type: Article

References (25)

1. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
2. Possibilities for the pharmacological exploitation of ischaemic preconditioning
3. Ischaemic preconditioning of myocardium: A new paradigm for clinical cardioprotection
4. Adaptation to myocardial stress in disease states: Is preconditioning a healthy heart phenomenon?
5. Cholesterol induced lipid accumulation in myocardial cells of rats
6. Comparative electron microscope studies of the myocardium in adult rats fed normal and cholesterol diets
7. Preventing and arresting coronary atherosclerosis
8. The loss of pacing-induced preconditioning in atherosclerotic rabbits: Role of hypercholesterolemia
9. Loss of pacing-induced preconditioning in rat hearts: Role of nitric oxide and cholesterol-enriched diet
10. Pravastatin restored the infarct size-limiting effect of ischemic preconditioning blunted by hypercholesterolemia in the rabbit model of myocardial infarction
11. Experimental hyperlipidemia prevents the protective effect of ischemic preconditioning on the contractility and responsiveness to phenylephrine of rat-isolated stunned papillary muscle
12. Heat shock proteins and the ischemic heart: An endogenous protective mechanism
13. Heat shock proteins and protection against myocardial ischemia
14. Attenuation of heat shock protein expression by coronary occlusion in hypertrophied hearts
15. Diminished heat shock response in the aged myocardium
16. Rapid pacing-induced preconditioning is recaptured by farnesol treatment in hearts of cholesterol-fed rats: Role of polyprenyl-derivatives and nitric oxide
17. The low-density lipoprotein receptor and cholesterol synthesis are affected differently by dietary cholesterol in the rat
18. Regulation of hepatic 7a-hydroxylase expression and response to dietary cholesterol in the rat and hamster
19. Classic preconditioning decreases the harmful accumulation of nitric oxide during ischemia and reperfusion in rat hearts
20. The rapid expression of myocardial hsp70 mRNA and the heat shock 70 kDa protein can be achieved after only a brief period of retrograde hyperthermic perfusion
21. Bimoclomol: A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects
22. Does the membrane’s physical state control the expression of heat shock and other genes?
23. Oxidant stress increases heat shock protein 70 mRNA in isolated perfused rat heart
24. Hypercholesterolemia impairs a detoxification mechanism against peroxynitrite and renders the vascular tissue more susceptible to oxidative injury
25. Nitric oxide, peroxynitrite, and cGMP in atherosclerosis-induced hypertensive rabbits: Beneficial effects of cicletanine