Foamed surfactant solution as a template for self-setting injectable hydroxyapatite scaffolds for bone regeneration

Acta Biomaterialia

Volumn 6, Issue 3, 2010, Pages 876-885

  Montufar, E B ^a,c   Traykova, T ^a   Gil, C ^a   Harr, I ^a   Almirall, A ^a   Aguirre, A ^a,b,c   Engel, E ^a,b,c   Planell, J A ^a,b,c   Ginebra, M P ^a,c  

^a Department of Materials Science and Metallurgy   (Spain)

^b INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^c BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

Calcium phosphate cement; Hydroxyapatite foam; Injectable material; Scaffold; Surfactant

Indexed keywords

BIOMECHANICS; BONE; CALCIUM PHOSPHATE; CELL PROLIFERATION; HYDROXYAPATITE; MIXING; POROSITY; TRANSMISSION CONTROL PROTOCOL;

BONE REGENERATION; CALCIUM PHOSPHATE CEMENT; HYDROXYAPATITE FOAM; INJECTABILITY; INJECTABLE MATERIALS; INJECTABLES; MINIMALLY INVASIVE SURGICAL; POLYSORBATE 80; SURGICAL TECHNIQUES; SYNTHETIC MATERIALS;

SURFACE ACTIVE AGENTS;

CALCIUM PHOSPHATE; FOAMING AGENT; HYDROXYAPATITE; POLYSORBATE 80;

ARTICLE; BIOCOMPATIBILITY; BONE CELL; BONE GRAFT; BONE REGENERATION; CALCIUM DEPLETION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; FOAM STABILITY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; OSSIFICATION; POROSITY; POWDER; PRIORITY JOURNAL; SOLID STATE; SOLUBILITY; TISSUE ENGINEERING;

EID: 75149177045     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.10.018     Document Type: Article

References (45)

1. Deville S., Saiz E., and Tomsia A.P. Freeze casting of hydroxyapatite scaffolds for bone tissue engineering. Biomaterials 27 (2006) 5480-5489
2. Studart A.R., Gonzenbach U.T., Tervoort E., and Gauckler L.J. Processing routes to macroporous ceramics: a review. J Am Ceram Soc 89 (2006) 1771-1789
3. Bouler J.M., Trecant M., Delecrin J., Royer J., Passuti N., and Daculsy G.J. Macroporous biphasic calcium phosphate: influence of five synthesis parameters on compressive strength. Biomed Mater Res 32 (1996) 603-609
4. Li S.H., De Wijn J.R., Layrolle P., and De Groot K. Synthesis of macroporous hydroxyapatite scaffolds for bone tissue engineering. J Biomed Mater Res 61 (2002) 109-120
5. Deville S., Saiz E., Nalla R.K., and Tomsia A.P. Freezing as a path to build complex composites. Science 311 (2006) 515-518
6. Gbureck U., Hölzel T., Doillon C.J., Müller F.A., and Barralet J.E. Direct printing of bioceramic implants with spatially localized angiogenic factors. Adv Mater 19 (2007) 795-800
7. Vitale-Brovarone C., Miola M., Balagna C., and Verne E. 3D-glass-ceramic scaffolds with antibacterial properties for bone grafting. Chem Eng J 137 (2008) 129-136
8. Assaker R. Minimal access spinal technologies: state-of-the-art, indications, and techniques. Joint Bone Spine 71 (2004) 459-469
9. Habib M., Baroud G., Gitzhofer F., and Bohner M. Mechanisms underlying the limited injectability of hydraulic calcium phosphate paste. Acta Biomaterialia 4 (2008) 1465-1471
10. Constantz B.R., et al. Skeletal repair by in situ formation of the mineral phase of bone. Science 267 (1995) 1796-1843
11. Ginebra M.P., Traykova T., and Planell J.A. Calcium phosphate bone cements as bone drug delivery systems: a review. J Control Release 113 (2006) 102-110
12. Frankenburg E.P., Goldstein S.A., Bauer T.W., Harris S.A., and Poser R.D. Biomechanical and histological evaluation of a calcium phosphate cement. J Bone Joint Surg Am 80 8 (1998) 1112-1124
13. Jansen J.A., de Ruijter J.E., Schaeken H.G., van der Waerden J.P.C.M., Planell J.A., and Driessens F.C.M. Evaluation of tricalciumphosphate/hydroxyapatite cement for tooth replacement: an experimental animal study. J Mater Sci Mater Med 6 (1995) 653-657
14. van der Waerden J.P.C.M., Ooms E.M., Wolke J.G.C., and Jansen J.A. Trabecular bone response to injectable calcium phosphate (Ca-P) cement. J Biomed Mater Res 61 (2002) 9-18
15. Takagi S., and Chow L.C. Formation of macropores in calcium phosphate cement implants. J Mater Sci Mater Med 12 (2001) 135-139
16. Xu H.H.K., Weir M.D., Burguera E.F., and Fraser A.M. Injectable and macroporous calcium phosphate cement scaffold. Biomaterials 27 (2006) 4279-4287
17. Xu H.H.K., and Quinn J.B. Calcium phosphate cement containing resorbable fibers for short-term reinforcement and macroporosity. Biomaterials 23 (2002) 193-202
18. Ruhé P.Q., Hedberg E.L., Padron N.T., Spauwen P.H.M., Jansen J.A., and Mikos A.G. Biocompatibility and degradation of poly(dl-lactic-co-glycolic acid)/calcium phosphate cement composites. J Biomed Mater Res 74A (2005) 533-544
19. Ginebra M.P., Delgado J.A., Harr I., Almirall A., Del Valle S., and Planell J.A. Factors affecting the structure and properties of an injectable self-setting calcium phosphate foam. J Biomed Mater Res 80A (2007) 351-361
20. Del Valle S., Miño N., Muñoz F., González A., Planell J.A., and Ginebra M.P. In vivo evaluation of an injectable macroporous calcium phosphate cement. J Mater Sci Mater Med 18 (2007) 353-361
21. De Groot A.S., and Scott D.W. Immunogenicity of protein therapeutics. Trends Immunol 28 (2007) 482-490
22. Koren E., Zuckerman L.A., and Mire-Sluis A.R. Immune response to therapeutic protein in humans - clinical significance, assessment and prediction. Curr Pharm Biotechnol 3 (2002) 349-360
23. Schellekens H. Immunogenicity of therapeutic proteins: clinical implications and future prospects. Clin Ther 24 (2002) 1720-1740
24. Aulton M.E. Pharmaceutics. 2nd ed. The science of dosage form design (2002), Churchill Livingstone, Edinburgh
25. Akers M.J. Excipient-drug interactions in parenteral formulations. J Pharm Sci 91 (2002) 2283-2300
26. Rowe R.C., Sheskey P.J., and Weller P.J. Handbook of pharmaceutical excipients. 4th ed. (2003), Pharmaceutical Press, London
27. Ash M., and Ash I. Handbook of pharmaceutical additives (1995), Gower Publishing, Aldershot
28. Almirall A., Larrecq G., Delgado J.A., Martínez S., Planell J.A., and Ginebra M.P. Fabrication of low temperature macroporous hydroxyapatite scaffolds. Biomaterials 25 (2004) 3671-3680
29. Ginebra M.P., Rilliard A., Fernández E., Elvira C., San Román J., and Planell J.A. Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug. J Biomed Mater Res 57 (2001) 113-118
30. Ginebra M.P., Fernandez E., Boltong M.G., Driessens F.C.M., Ginebra J., De Maeyer E.A.P., et al. Setting reaction and hardening of an apatitic calcium phosphate cement. J Dent Res 76 (1997) 905-912
31. Sarda S., Nilsson M., Balcells M., and Fernández E. Influence of surfactant molecules as air-entraining agent for bone cement macroporosity. J Biomed Mater Res 65A (2003) 215-221
32. Schramm L.L. Emulsions, foams and suspensions (2005), Wiley-VCH Verlag, Weinheim
33. Porter M.R. Handbook of surfactants. 2nd ed. (1994), Chapman & Hall, Glasgow
34. Sigma P5188 product information sheet, 2007.
35. Ginebra M.P., Fernández E., Driessens F.C.M., and Planell J.A. Modeling of the hydrolysis of α-tricalcium phosphate. J Am Ceram Soc 82 (1999) 2808-2812
36. Coors E.A., Seybold H., Merk H.F., and Mahler V. Polysorbate 80 in medical products and nonimmunologic anaphylactoid reactions. Ann Allergy Asthma Immunol 95 (2005) 593-599
37. Shelley W.B., Talanin N., and Shelley E.D. Polysorbate 80 hypersensitivity. Lancet 345 (1995) 1312-1313
38. Floyd A.G. Top ten considerations in the development of parenteral emulsions. Pharm Sci Tech Today 2 (1999) 134-143
39. Barralet J.E., Hofmann M., Grover L.M., and Gbureck U. High-strength apatitic cement by modification with α-hydroxy acid salts. Adv Mater 15 (2003) 2091-2094
40. Burstein A.H., Reilly D.T., and Martens M. Ageing of bone tissue: mechanical properties. J Bone Joint Surg 58A (1976) 82-86
41. Carter D.R., and Hayes W.C. The behavior of bone as a two-phase porous structure. J Bone Joint Surg 59A (1977) 954-962
42. Bohner M., and Baroud G. Injectability of calcium phosphate pastes. Biomaterials 26 (2005) 1553-1563
43. Gbureck U., Barralet J.E., Spatz K., Grover L.M., and Thull R. Ionic modification of calcium phosphate cement viscosity. Part I. Hypodermic injection and strength improvement of an apatite cement. Biomaterials 25 (2004) 2187-2195
44. Leroux L., Hatim Z., Freche M., and Lacout J.L. Effects of various adjuvants (lactic acid, glycerol and chitosan) on the injectability of a calcium phosphate cement. Bone 25 (1999) 31-34
45. Engel E., Del Valle S., Aparicio C., Altankov G., Asin L., Planell J.A., et al. Discerning the role of topography and ion exchange in cell response of bioactive tissue engineering scaffolds. Tissue Eng A 14 (2008) 1341-1351