Immunohistochemical and proteomic evaluation of nuclear ubiquitous casein and cyclin-dependent kinases substrate in invasive ductal carcinoma of the breast

Journal of Biomedicine and Biotechnology

Volumn 2009, Issue , 2009, Pages

  Ziókowski, Piotr ^a   Gamian, Elbieta ^a   Osiecka, Beata ^a   Zougman, Alexandre ^b   Wiśniewski, Jacek R ^b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN; CHROMOSOME PROTEIN; CYCLIN DEPENDENT KINASE; HIGH MOBILITY GROUP A PROTEIN; PROTEIN NUCKS; UNCLASSIFIED DRUG; CANCER ANTIBODY; NUCKS PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN;

ARTICLE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRADUCTAL CARCINOMA; INVASIVE CARCINOMA; PROTEIN EXPRESSION; PROTEOMICS; ANTIBODY SPECIFICITY; BREAST TUMOR; FEMALE; IMMUNOLOGY; METABOLISM; PAGET NIPPLE DISEASE; PATHOLOGY;

ANTIBODIES, NEOPLASM; ANTIBODY SPECIFICITY; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEOMICS;

EID: 75149166083     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2009/919645     Document Type: Article

References (30)

1. Stvold A. C., Norum J. H., Mathiesen S., Wanvik B., Sefland I., Grundt K., Molecular cloning of a mammalian nuclear phosphoprotein NUCKS, which serves as a substrate for Cdk1 in vivo European Journal of Biochemistry 2001 268 8 2430 2440
2. Grundt K., Haga I. V., Aleporou-Marinou V., Drosos Y., Wanvik B., stvold A. C., Characterisation of the NUCKS gene on human chromosome 1q32.1 and the presence of a homologous gene in different species Biochemical and Biophysical Research Communications 2004 323 3 796 801
3. Winiewski J. R., Schwanbeck R., High mobility group I/Y: multifunctional chromosomal proteins causally involved in tumor progression and malignant transformation (review) International Journal of Molecular Medicine 2000 6 4 409 419
4. Fusco A., Fedele M., Roles of HMGA proteins in cancer Nature Reviews Cancer 2007 7 12 899 910
5. Reeves R., Beckerbauer L., HMGI/Y proteins: flexible regulators of transcription and chromatin structure Biochimica et Biophysica Acta 2001 1519 1-2 13 29
6. Ashar H. R., Fejzo M. S., Tkachenko A., Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains Cell 1995 82 1 57 65
7. Schoenmakers E. F., Wanschura S., Mols R., Bullerdiek J., Van den Berghe H., Van de Ven W. J. M., Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours Nature Genetics 1995 10 4 436 444
8. Heim S., Nilbert M., Vanni R., A specific translocation, t(12;14)(q14-15;q23-24), characterizes a subgroup of uterine leiomyomas Cancer Genetics and Cytogenetics 1988 32 1 13 17
9. Hennig Y., Rogalla P., Wanschura S., HMGIC expressed in a uterine leiomyoma with a deletion of the long arm of chromosome 7 along with a 12q14-15 rearrangement but not in tumors showing del(7) as the sole cytogenetic abnormality Cancer Genetics and Cytogenetics 1997 96 2 129 133
10. Kazmierczak B., Rosigkeit J., Wanschura S., HMGI-C rearrangements as the molecular basis for the majority of pulmonary chondroid hamartomas: a survey of 30 tumors Oncogene 1996 12 3 515 521
11. Staats B., Bonk U., Wanschura S., A fibroadenoma with a t(4;12) (q27;q15) affecting the HMGI-C gene, a member of the high mobility group protein gene family Breast Cancer Research and Treatment 1996 38 3 299 303
12. Pierantoni G. M., Finelli P., Valtorta E., Giardino D., Rodeschini O., Esposito F., High-mobility group A2 gene expression is frequently induced in non-functioning pituitary adenomas (NFPAs), even in the absence of chromosome 12 polysomy Endocrine-Related Cancer 2005 12 4 867 874
13. Pierantoni G. M., Agosti V., Fedele M., High-mobility group A1 proteins are overexpressed in human leukaemias Biochemical Journal 2003 372 1 145 150
14. Reeves R., Beckerbauer L. M., HMGA proteins as therapeutic drug targets Progress in Cell Cycle Research 2003 5 279 286
15. Belge G., Meyer A., Klemke M., Upregulation of HMGA2 in thyroid carcinomas: a novel molecular marker to distinguish between benign and malignant follicular neoplasias Genes Chromosomes and Cancer 2008 47 1 56 63
16. Schaner M. E., Ross D. T., Ciaravino G., Gene expression patterns in ovarian carcinomas Molecular Biology of the Cell 2003 14 11 4376 4386
17. Grundt K., Skjeldal L., Anthonsen H. W., Skauge T., Huitfeldt H. S., stvold A. C., A putative DNA-binding domain in the NUCKS protein Archives of Biochemistry and Biophysics 2002 407 2 168 175
18. Grundt K., Haga I. V., Huitfeldt H. S., stvold A. C., Identification and characterization of two putative nuclear localization signals (NLS) in the DNA-binding protein NUCKS Biochimica et Biophysica Acta 2007 1773 9 1398 1406
19. Winiewski J. R., Zougman A., Krger S., Constitutive and dynamic phosphorylation and acetylation sites on NUCKS, a hypermodified nuclear protein, studied by quantitative proteomics Proteins 2008 73 3 710 718
20. Trojani M., A Color Atlas of Breast Histopathology 1991 Philadelphia, Pa, USA J. B. Lippincott
21. Zougman A., Winiewski J. R., Beyond linker histones and high mobility group proteins: global profiling of perchloric acid soluble proteins Journal of Proteome Research 2006 5 4 925 934
22. Shevchenko A., Wilm M., Vorm O., Mann M., Mass spectrometric sequencing of proteins from silver-stained polyacrylamide gels Analytical Chemistry 1996 68 5 850 858
23. Rappsilber J., Ishihama Y., Mann M., Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics Analytical Chemistry 2003 75 3 663 670
24. Winiewski J. R., Zougman A., Krger S., Mann M., Mass spectrometric mapping of linker histone H1 variants reveals multiple acetylations, methylations, and phosphorylation as well as differences between cell culture and tissue Molecular and Cellular Proteomics 2007 6 1 72 87
25. Perkins D. N., Pappin D. J. C., Creasy D. M., Cottrell J. S., Probability-based protein identification by searching sequence databases using mass spectrometry data Electrophoresis 1999 20 18 3551 3567
26. Kuenen-Boumeester V., Van der Kwast T. H., Van Laarhoven H. A. J., Henzen-Logmans S. C., Ki-67 staining in histological subtypes of breast carcinoma and fine needle aspiration smears Journal of Clinical Pathology 1991 44 3 208 210
27. Miller N. A., Chapman J.-A., Fish E. B., In situ duct carcinoma of the breast: clinical and histopathologic factors and association with recurrent carcinoma Breast Journal 2001 7 5 292 302
28. Buerger H., Simon R., Schafer K.-L., Genetic relation of lobular carcinoma in situ, ductal carcinoma in situ, and associated invasive carcinoma of the breast Molecular Pathology 2000 53 3 118 121
29. Thompson H. G. R., Harris J. W., Wold B. J., Quake S. R., Brody J. P., Identification and confirmation of a module of coexpressed genes Genome Research 2002 12 10 1517 1522
30. Sargent L. M., Ensell M. X., Ostvold A.-C., Chromosomal changes in high-and low-invasive mouse lung adenocarcinoma cell strains derived from early passage mouse lung adenocarcinoma cell strains Toxicology and Applied Pharmacology 2008 233 1 81 91