Risk of breast cancer not increased in translocation 11;22 carriers: Analysis of 80 pedigrees

American Journal of Medical Genetics, Part A

Volumn 152, Issue 1, 2010, Pages 212-214

  Carter, Melissa T ^a   Barrowman, Nicholas J ^a   St Pierre, Stephanie A ^b   Emanuel, Beverly S ^c   Boycott, Kym M ^a  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b Research Institute ^*  (Canada)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; BREAST CANCER; CANCER INCIDENCE; CANCER REGISTRY; CANCER RISK; CHROMOSOME 11Q; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME MAP; CHROMOSOME TRANSLOCATION; COLORECTAL CANCER; DISEASE CARRIER; ESOPHAGUS CANCER; FAMILY HISTORY; FEMALE; HETEROZYGOSITY; HUMAN; KIDNEY CANCER; LETTER; LEUKEMIA; MELANOMA; MONOSOMY; OVARY CANCER; PEDIGREE; PRIORITY JOURNAL; PROSTATE CANCER; QUESTIONNAIRE; UTERINE CERVIX CANCER; UTERUS CANCER; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER GROWTH; CANCER SCREENING; CELL ADHESION; CHROMOSOME 22; CHROMOSOME DISORDER; CHROMOSOME TRANSLOCATION 11; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE MAPPING; HETEROZYGOSITY LOSS; INFERTILITY; MEDICAL INFORMATION; PEDIGREE ANALYSIS; RISK FACTOR; SPONTANEOUS ABORTION; SUPPORT GROUP; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 22; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HETEROZYGOTE; HUMANS; MALE; PEDIGREE; TRANSLOCATION, GENETIC;

EID: 75149161603     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.33166     Document Type: Letter

References (21)

1. Aitken JF, Youl P, Green A, MacLennan R, Martin NG. 1996. Accuracy of case-reported family history of melanoma in Queensland, Australia. Melanoma Res 6:313-317.
2. Carter MT, St-Pierre SA, Zackai EH, Emanuel BS, Boycott KM. 2009. Phenotypic delineation of Emanuel syndrome (Supernumerary derivative 22 syndrome): Clinical features of 63 individuals. Am J Med Genet Part A 149A:1712-1721.
3. Fraccaro M, Lindsten J, Ford CE, Iselius L. 1980. The 11q;22q translocation: A European collaborative analysis of 43 cases. Hum Genet 56:21-51.
4. Gentile M, Ahnström M, Schön F, Wingren S. 2001. Candidate tumour suppressor genes at 11q23-q24 in breast cancer: Evidence of alterations in PIG8, a gene involved in p53-induced apoptosis. Oncogene 20: 7753-7760.
5. Gustafson CE, Young J, Leggett B, Searle J, Chenevix-Trench G. 1994. Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours. Br J Cancer 70:395-397.
6. Herbst RA, Larson A, Weiss J, Cavanee WK, Hampton GM, Arden KC. 1995. A defined region of loss of heterozygosity at 11q23 in cutaneous malignant melanoma. Cancer Res 55:2494-2496.
7. Jobanputra V, Chung WK, Hacker AM, Emanuel BS, Warburton D. 2005. A unique case of der(11)t(11;22),-22 arising from 3:1 segregation of a maternal t(11;22) in a family with co-segregation of the translocation and breast cancer. Prenat Diagn 25:683-686.
8. Johnson JP, Rummel MM, Rothbacher U, Sers C. 1996. MUC18: A cell adhesion molecule with a potential role in tumor growth and tumor cell dissemination. Curr Top Microbiol Immunol 213:95-105.
9. Kurahashi H, Shaikh TH, Zackai EH, Celle L, Driscoll DA, Budarf ML, Emanuel BS. 2000. Tightly clustered 11q23 and 22q11 breakpoints permit PCR-based detection of the recurrent constitutional t(11;22). Am J Hum Genet 67:763-768.
10. Kuske MDA, Johnson JP. 1999. Assignment of the human melanoma cell adhesion molecule gene (MCAM) to chromosome 11 band q23.3 by radiation hybrid mapping. Cytogenet Cell Genet 87:258.
11. Lindblom A, Sandelin K, Iselius L, Dumanski J, White I, Nordenskjold M, Larsson C. 1994. Predisposition for breast cancer in carriers of constitutional translocation 11q;22q. Am J Hum Genet 54:871-876.
12. Martin ES, Cesari R, Pentimalli F, Yoder K, Fishel R, Himelstein AL, Martin SE, Godwin AK, Negrini M, Croce CM. 2003. The BCSC-1 locus at chromosome 11q23-q24 is a condidate tumor suppressor gene. PNAS 100:11517-11522.
13. Murff HJ, Spigel DR, Syngal S. 2004. Does this patient have a family history of cancer?: An evidence-based analysis of the accuracy of family cancer history. JAMA 292:1480-1489.
14. Negrini M, Rasio D, Hampton GM, Sabbioni S, Rattan S, Carter SL, Rosenberg AL, Schwartz GF, Shiloh Y, Cavanee WK, et al. 1995. Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: Identification of a new region at 11q23.3. Cancer Res 55:3003-3007.
15. Rasio D, Negrini M, Manenti G, Dragani TA, Croce CM. 1995. Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: Identification of three independent regions. Cancer Res 55:3988-3991.
16. Rothman KJ, Boice JD Jr. 1979. Epidemiologic analysis with a programmable calculator. Bethesda, MD: National Institutes of Health. pp. 31-32.
17. Sijmons RH, Boonstra AE, Reefhuis J, Hordijk-Hos JM, de Walle HEK, Oosterwijk JC, Cornel MC. 2000. Accuracy of family history of cancer: Clinical genetic implications. Eur J Hum Genet 8:181-186.
18. United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. 2008. United States Cancer Statistics: 1999-2004 Incidence, WONDER Online Database. Available at http://wonder.cdc.gov/cancer-v2004.html. Accessed on February 6, 2009.
19. Wang SS, Esplin ED, Li JL, Huang L, Gazdar A, Minna J, Evans GA. 1998. Alterations of the PPP2R1B gene in human lung and colon cancer. Science 282:284-288.
20. Wieland I, Muschke P, Volleth M, Ropke A, Pelz A-F, Stumm M, Wieacker P. 2006. High incidence of familial breast cancer segregates with constitutional t(11;22)(q23;q11). Genes Chromosomes Cancer 45: 945-949.
21. Zackai EH, Emanuel BS. 1980. Site-specific reciprocal translocation, t(11;22)(q23;q11), in several unrelated families with 3:1 meiotic disjunction. Am J Med Genet 7:507-521.