Assignment of the human melanoma cell adhesion molecule gene (MCAM) to chromosome 11 band q23.3 by radiation hybrid mapping

Cytogenetics and Cell Genetics

Volumn 87, Issue 3-4, 1999, Pages 258-

  Kuske, M D A ^a   Johnson, Judith P ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b Institute for Immunology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE;

ARTICLE; CHROMOSOME 11Q; GENE MAPPING; HUMAN; MELANOMA CELL; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD146; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; CHROMOSOMES, HUMAN, PAIR 11; CRICETINAE; GENETIC MARKERS; HUMANS; HYBRID CELLS; LOD SCORE; MELANOMA; MEMBRANE GLYCOPROTEINS; NEOPLASM METASTASIS; NEURAL CELL ADHESION MOLECULES; PHYSICAL CHROMOSOME MAPPING; POLYMERASE CHAIN REACTION;

EID: 0343503052     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Herbst RA, Larson A, Weiss J, Cavenee WK, Hampton GM, Arden KC: A defined region of loss of heterozygosity at 11q23 in cutaneous malignant melanoma. Cancer Res 55:2494-2496 (1995).
2. Johnson JP, Rummel MM, Rothbächer U, Sers C: MUC18, a cell adhesion molecule with a potential role in tumor growth and tumor cell dissemination. Curr Top Microbiol Immunol 213:95-105 (1996).
3. Schlagbauer-Wadl H, Jansen B, Müller M, Polterauer P, Wolff K, Eichler H-G, Pehamberger H, Konak E, Johnson JP: The melanoma progression marker MUC18/MCAM/CD146 mediates experimental but not spontaneous metastasis of human melanoma in SCID mice. Int J Cancer 81:951-955 (1999).
4. Sers C, Kirsch K, Rothbächer U, Riethmüller G, Johnson JP: The gene encoding the melanoma-associated glycoprotein MUC18 displays a unique structure among the members of the immunoglobulin superfamily. Proc natl Acad Sci, USA 90:8514-8518 (1993).
5. Shih IM, Elder DE, Speicher D, Johnson JP, Herlyn M: Isolation and functional characterization of the A32 melanoma-associated antigen. Cancer Res 54:2514-2520 (1994).
6. Xie S, Luca M, Huang S, Gutman M, Reich R, Johnson JP, Bar-Eli M: Expression of MCAM/MUC18 by human melanoma cells leads to increased tumor growth and metastasis. Cancer Res 57:2295-2303 (1997).