Inhibition of tumor progression locus 2 protein kinase suppresses receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis through down-regulation of the c-Fos and nuclear factor of activated T cells c1 genes

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 1, 2010, Pages 133-137

  Hirata, Kazuya ^a   Taki, Hirofumi ^a   Shinoda, Kouichiro ^a   Hounoki, Hiroyuki ^a   Miyahara, Tatsuro ^a   Tobe, Kazuyuki ^a   Ogawa, Hirofumi ^a   Mori, Hisashi ^a   Sugiyama, Eiji ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

c Fos; Nuclear factor of activated T cells c1; Osteoclastogenesis; Receptor activator of nuclear factor B ligand; Tumor progression locus 2

Indexed keywords

1,7 NAPHTYRIDINE 3 CARBONITRILE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; COLONY STIMULATING FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FOS; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NFAT; TUMOR PROGRESSION LOCUS 2 PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DENTIN; DOSE RESPONSE; DOWN REGULATION; ENZYME INHIBITION; ENZYME REPRESSION; GENE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; OSTEOCLAST; PHOSPHORYLATION;

ACID PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CELL LINE; DENTIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION; GENES, FOS; ISOENZYMES; LIGANDS; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MAP KINASE KINASE KINASES; MICE; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; RANK LIGAND;

EID: 75149161029     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.133     Document Type: Article

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