-
1
-
-
65549107808
-
Etravirine: A second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant strains of HIV
-
D.S. Schiller, and M. Youssef-Bessler Etravirine: a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI-resistant strains of HIV Clin Ther 31 2009 692 704
-
(2009)
Clin Ther
, vol.31
, pp. 692-704
-
-
Schiller, D.S.1
Youssef-Bessler, M.2
-
2
-
-
75149197282
-
-
Documento EMEA/H/C/900 [consultado 14-7-2009]. Disponible en:
-
Informe público europeo de evaluación (EPAR), Intelence European Medicines Agency (EMEA). Documento EMEA/H/C/900 [consultado 14-7-2009]. Disponible en: http://www.emea.europa.eu
-
Informe Público Europeo de Evaluación (EPAR), Intelence
-
-
-
3
-
-
77957341685
-
Mass-balance of 14C-labelled TMC125 in healthy volunteers
-
Abstract 78
-
M. Schöller-Gyre, A. Raaof, G. Mannens, S. Bollen, T.N. Kakuda, D. Woodfall, et al. Mass-balance of 14C-labelled TMC125 in healthy volunteers 8th International Workshop on Clinical Pharmacology of HIV Therapy Budapest 2007 Apr 16-18. Abstract 78
-
8th International Workshop on Clinical Pharmacology of HIV Therapy Budapest 2007 Apr 16-18
-
-
Schöller-Gyre, M.1
Raaof, A.2
Mannens, G.3
Bollen, S.4
Kakuda, T.N.5
Woodfall, D.6
-
5
-
-
75149168806
-
No significant interaction between TMC125 and didanosine in healthy volunteers
-
Abstract WePe3.3C16
-
M. Schöller-Gyre, R. Hoetelmans, S. Bollen, K. Vandermeulen, M. Peeters, L. Bastiaanse, et al. No significant interaction between TMC125 and didanosine in healthy volunteers 3rd International AIDS Society Conference on HIV Pathogenesis and Treatment Rio de Janeiro 2005 Abstract WePe3.3C16
-
3rd International AIDS Society Conference on HIV Pathogenesis and Treatment Rio de Janeiro 2005
-
-
Schöller-Gyre, M.1
Hoetelmans, R.2
Bollen, S.3
Vandermeulen, K.4
Peeters, M.5
Bastiaanse, L.6
-
6
-
-
75149136514
-
Pharmacokinetic evaluation of the interaction between TMC125 and tenofovir disoproxil fumarate
-
Abstract A-371
-
M. Schöller-Güyre, C. Debroye, B. Woodfall, J. Witek, G. De Smedt, and R.M. Hoetelmans Pharmacokinetic evaluation of the interaction between TMC125 and tenofovir disoproxil fumarate 46th Interscience Conference on Antimicrobial Agents and Chemotherapy San Francisco (CA) 2006 Sep 27-30. Abstract A-371
-
46th Interscience Conference on Antimicrobial Agents and Chemotherapy San Francisco (CA) 2006 Sep 27-30
-
-
Schöller-Güyre, M.1
Debroye, C.2
Woodfall, B.3
Witek, J.4
De Smedt, G.5
Hoetelmans, R.M.6
-
7
-
-
77957355346
-
TMC125 in combination with other medications: Summary of drug-drug interaction studies
-
Oral presentation PL5.2
-
T. Kakuda, M. Schöller-Gyüre, B. Woodfall, G. De Smedt, M. Peeters, K. Vandermeulen, et al. TMC125 in combination with other medications: summary of drug-drug interaction studies 8th International Congress on Drug Therapy in HIV Infection Glasgow. 12-16 November 2006 Oral presentation PL5.2
-
8th International Congress on Drug Therapy in HIV Infection Glasgow. 12-16 November 2006
-
-
Kakuda, T.1
Schöller-Gyüre, M.2
Woodfall, B.3
De Smedt, G.4
Peeters, M.5
Vandermeulen, K.6
-
8
-
-
70349542703
-
Pharmacokinetics and safety of adding TMC125 to stable regimens of saquinavir, lopinavir and ritonavir in HIV+adults
-
Abstract 575
-
M. Harris, C. Zala, S. Ramírez, B. Woodfall, M. Peeters, M. Scholler, et al. Pharmacokinetics and safety of adding TMC125 to stable regimens of saquinavir, lopinavir and ritonavir in HIV+adults 13th Conference on Retroviruses and Opportunistic Infections Denver (CO). 5-8 Feb 2006 Abstract 575
-
13th Conference on Retroviruses and Opportunistic Infections Denver (CO). 5-8 Feb 2006
-
-
Harris, M.1
Zala, C.2
Ramírez, S.3
Woodfall, B.4
Peeters, M.5
Scholler, M.6
-
9
-
-
75149152864
-
Pharmacokinetics of TMC125 with atazanavir and atazanavir/ritonavir
-
Abstract P278
-
M. Schöller Gyüre, B. Woodffall, T. De Marez, G. De Smedt, M. Peeters, K. Vandermeulen, et al. Pharmacokinetics of TMC125 with atazanavir and atazanavir/ritonavir 8th Internacional Congress on Drug Therapy in HIV Infection Glasgow. Nov 12-16 2006 Abstract P278
-
8th Internacional Congress on Drug Therapy in HIV Infection Glasgow. Nov 12-16 2006
-
-
Schöller Gyüre, M.1
Woodffall, B.2
De Marez, T.3
De Smedt, G.4
Peeters, M.5
Vandermeulen, K.6
-
10
-
-
33746966338
-
Significant decrease in TMC125 exposures when co-administered with tipranavir in healthy subjects
-
Abstract 583
-
M. Schöller, M. Kraft, R. Hoetelmans, V. Vyncke, K. Vandermeulen, M. Peeters, et al. Significant decrease in TMC125 exposures when co-administered with tipranavir in healthy subjects 13th Conference on Retroviruses and Opportunistic Infections Denver (CO). 5-8 Feb 2006 Abstract 583
-
13th Conference on Retroviruses and Opportunistic Infections Denver (CO). 5-8 Feb 2006
-
-
Schöller, M.1
Kraft, M.2
Hoetelmans, R.3
Vyncke, V.4
Vandermeulen, K.5
Peeters, M.6
-
11
-
-
70349521775
-
Pharmacokinetics of amprenavir and TMC125 in HIV infected volunteers receiving TMC125 with fosamprenavir/ritonavir
-
Abstract A-370
-
M. Schöller-Gyüre, B. Woodfall, S. Bollen, M. Peeters, K. Vandermeulen, and R. Hoetelmans Pharmacokinetics of amprenavir and TMC125 in HIV infected volunteers receiving TMC125 with fosamprenavir/ritonavir 46th Interscience Conference on Antimicrobial Agents and Chemotherapy San Francisco (CA) 2006 Sep 27-30. Abstract A-370
-
46th Interscience Conference on Antimicrobial Agents and Chemotherapy San Francisco (CA) 2006 Sep 27-30
-
-
Schöller-Gyüre, M.1
Woodfall, B.2
Bollen, S.3
Peeters, M.4
Vandermeulen, K.5
Hoetelmans, R.6
-
13
-
-
75149186484
-
Pharmacokinetic interaction between etravirine and lopinavir/ritonavir
-
A1-1298
-
M. Schöller-Gyüre, T.N. Kakuda, S.H. Akuma, I. De Clero, G. De Smedt, K. Spittaels, et al. Pharmacokinetic interaction between etravirine and lopinavir/ritonavir 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) San Francisco, California, USA. September 2009 A1-1298
-
49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) San Francisco, California, USA. September 2009
-
-
Schöller-Gyüre, M.1
Kakuda, T.N.2
Akuma, S.H.3
De Clero, I.4
De Smedt, G.5
Spittaels, K.6
-
14
-
-
34347354196
-
Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial
-
DOI 10.1016/S0140-6736(07)61048-4, PII S0140673607610484
-
A. Lazzarin, T. Campbell, B. Clotet, M. Johnson, C. Katlama, and A. Moll Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo-controlled trial Lancet 370 2007 39 48 (Pubitemid 47017467)
-
(2007)
Lancet
, vol.370
, Issue.9581
, pp. 39-48
-
-
Lazzarin, A.1
Campbell, T.2
Clotet, B.3
Johnson, M.4
Katlama, C.5
Moll, A.6
Towner, W.7
Trottier, B.8
Peeters, M.9
Vingerhoets, J.10
De Smedt, G.11
Baeten, B.12
Beets, G.13
Sinha, R.14
Woodfall, B.15
-
15
-
-
34347327010
-
Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial
-
DOI 10.1016/S0140-6736(07)61047-2, PII S0140673607610472
-
J.V. Madruga, P. Cahn, B. Grinsztejn, R. Haubrich, J. Lalezari, and A. Mills Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-1: 24-week results from a randomised, double-blind, placebo-controlled trial Lancet 370 2007 29 38 (Pubitemid 47017466)
-
(2007)
Lancet
, vol.370
, Issue.9581
, pp. 29-38
-
-
Madruga, J.V.1
Cahn, P.2
Grinsztejn, B.3
Haubrich, R.4
Lalezari, J.5
Mills, A.6
Pialoux, G.7
Wilkin, T.8
Peeters, M.9
Vingerhoets, J.10
De Smedt, G.11
Leopold, L.12
Trefiglio, R.13
Woodfall, B.14
-
16
-
-
34547780413
-
Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers
-
M. Schöller-Gyüre, T.N. Kakuda, V. Sekar, B. Woodfall, G. De Smedt, and E. Lefebvre Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers Antivir Ther 12 2007 789 796 (Pubitemid 47235493)
-
(2007)
Antiviral Therapy
, vol.12
, Issue.5
, pp. 789-796
-
-
Scholler-Gyure, M.1
Kakuda, T.N.2
Sekar, V.3
Woodfall, B.4
De Smedt, G.5
Lefebvre, E.6
Peeters, M.7
Hoetelmans, R.M.8
-
17
-
-
77954829208
-
Pharmacokinetics of once-daily etravirine (ETR) without and with once-daily darunavir/ritonavir (DRV/r) in antiretroviral-naïve HIV-1 infected adults
-
Abstract P245
-
J. Lalezari, E. DeJesus, O. Osiyemi, P. Ruane, Z. Haigney, R. Ryan, et al. Pharmacokinetics of once-daily etravirine (ETR) without and with once-daily darunavir/ritonavir (DRV/r) in antiretroviral-naïve HIV-1 infected adults 9th International Congress on Drug Therapy in HIV Infection Glasgow. November 9-13 2008 Abstract P245
-
9th International Congress on Drug Therapy in HIV Infection Glasgow. November 9-13 2008
-
-
Lalezari, J.1
DeJesus, E.2
Osiyemi, O.3
Ruane, P.4
Haigney, Z.5
Ryan, R.6
-
18
-
-
75149121008
-
An open, randomized, two period, crossover study in 2 cohorts to investigate the effect of steady state TMC125 and the combination of TMC/darunavir/ritonavir on the steady state pharmacokinetics of oral maraviroc in healthy subjects
-
Abstract P4.3/02
-
J. Davis, M. Schöller-Gyre, T.N. Kakuda, C. Ridgway, S. Tweedy, N. Ndongo, et al. An open, randomized, two period, crossover study in 2 cohorts to investigate the effect of steady state TMC125 and the combination of TMC/darunavir/ritonavir on the steady state pharmacokinetics of oral maraviroc in healthy subjects 11th European AIDS Conference Madrid, Spain. Oct 24-27 2007 Abstract P4.3/02
-
11th European AIDS Conference Madrid, Spain. Oct 24-27 2007
-
-
Davis, J.1
Schöller-Gyre, M.2
Kakuda, T.N.3
Ridgway, C.4
Tweedy, S.5
Ndongo, N.6
-
19
-
-
67649670094
-
Etravirine-raltegravir, a marked interaction in HIV-1 infected patients: About four cases
-
A. Menard, C. Solas, S. Mokthari, S. Bregigeon, M.P. Drogoul, C. Tamalet, et al. Etravirine-raltegravir, a marked interaction in HIV-1 infected patients: about four cases AIDS 23 2009 869 871
-
(2009)
AIDS
, vol.23
, pp. 869-871
-
-
Menard, A.1
Solas, C.2
Mokthari, S.3
Bregigeon, S.4
Drogoul, M.P.5
Tamalet, C.6
-
20
-
-
57049148690
-
Minimal pharmacokinetic interaction between the human immunodeficiency virus non-nucleoside reverse transcriptase inhibitor etravirine and the integrase inhibitor raltegravir in healthy subjects
-
M.S. Anderson, T.N. Kakuda, W. Hanley, J. Miller, J.T. Kost, R. Stoltz, et al. Minimal pharmacokinetic interaction between the human immunodeficiency virus non-nucleoside reverse transcriptase inhibitor etravirine and the integrase inhibitor raltegravir in healthy subjects Antimicrob Agents Chemother 52 2008 4228 4232
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 4228-4232
-
-
Anderson, M.S.1
Kakuda, T.N.2
Hanley, W.3
Miller, J.4
Kost, J.T.5
Stoltz, R.6
-
21
-
-
65749106963
-
Virological and immunological response in HIV-1-infected patients with multiple treatment failures receiving raltegravir and optimized background therapy, ANRS CO3 Aquitaine Cohort
-
L. Wittkop, D. Breilh, D. Da Silva, P. Duffau, P. Mercié, I. Raymond, et al. Virological and immunological response in HIV-1-infected patients with multiple treatment failures receiving raltegravir and optimized background therapy, ANRS CO3 Aquitaine Cohort J Antimicrob Chemother 63 2009 1251 1255
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 1251-1255
-
-
Wittkop, L.1
Breilh, D.2
Da Silva, D.3
Duffau, P.4
Mercié, P.5
Raymond, I.6
-
22
-
-
58149489322
-
Pharmacokinetics of elvitegravir and etravirine following coadministration of ritonavir-boosted elvitegravir and etravirine
-
S. Ramanathan, T.N. Kakuda, R. Mack, S. West, and B.P. Kearney Pharmacokinetics of elvitegravir and etravirine following coadministration of ritonavir-boosted elvitegravir and etravirine Antivir Ther 13 2008 1011 1017
-
(2008)
Antivir Ther
, vol.13
, pp. 1011-1017
-
-
Ramanathan, S.1
Kakuda, T.N.2
MacK, R.3
West, S.4
Kearney, B.P.5
-
23
-
-
75149192594
-
Pharmacokinetic interaction between TMC125 and rifabutin
-
Abstract 963
-
M. Schöller-Gyüre, B. Woodfall, C. Debroye, T. De Marez, M. Peeters, K. Vandermeulen, et al. Pharmacokinetic interaction between TMC125 and rifabutin 44th Annual Meeting of the Infectious Diseases Society of America Toronto. 12-15 Oct 2006 Abstract 963
-
44th Annual Meeting of the Infectious Diseases Society of America Toronto. 12-15 Oct 2006
-
-
Schöller-Gyüre, M.1
Woodfall, B.2
Debroye, C.3
De Marez, T.4
Peeters, M.5
Vandermeulen, K.6
-
24
-
-
75149185403
-
-
[consultado 14-7-2009]. Disponible en:
-
Etravirine interactions chart [consultado 14-7-2009]. Disponible en: http://www.hiv-druginteractions.org
-
Etravirine Interactions Chart
-
-
-
25
-
-
39149138092
-
Pharmacokinetic and pharmacodynamic study of the concomitant administration of methadone and TMC125 in HIV-negative volunteers
-
DOI 10.1177/0091270007310387
-
M. Schöller-Gyüre, W. Van den Brink, T.N. Kakuda, B. Woodfall, G. De Smedt, and H. Vanaken Pharmacokinetic and pharmacodynamic study of the concomitant administration of methadone and TMC125 in HIV-negative volunteers J Clin Pharmacol 48 2008 322 329 (Pubitemid 351257768)
-
(2008)
Journal of Clinical Pharmacology
, vol.48
, Issue.3
, pp. 322-329
-
-
Scholler-Gyure, M.1
Van Den Brink, W.2
Kakuda, T.N.3
Woodfall, B.4
De Smedt, G.5
Vanaken, H.6
Stevens, T.7
Peeters, M.8
Vandermeulen, K.9
Hoetelmans, R.M.W.10
-
26
-
-
66949111695
-
Pharmacokinetic interaction between the non-nucleoside reverse transcriptase inhibitor TMC125 and atorvastatin in HIV-negative volunteers
-
Abstract WEPEA 106
-
M. Schöller-Gyüre, T.N. Kakuda, G. De Smedt, B. Woodfall, S. Bollen, M. Peeters, et al. Pharmacokinetic interaction between the non-nucleoside reverse transcriptase inhibitor TMC125 and atorvastatin in HIV-negative volunteers 4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention Sydney. 22-25 Jul 2007 Abstract WEPEA 106
-
4th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention Sydney. 22-25 Jul 2007
-
-
Schöller-Gyüre, M.1
Kakuda, T.N.2
De Smedt, G.3
Woodfall, B.4
Bollen, S.5
Peeters, M.6
-
28
-
-
51649083570
-
A pharmacokinetic study of etravirine (TMC125) co-administered with ranitidine and omeprazole in HIV-negative volunteers
-
M. Schöller-Gyüre, T.N. Kakuda, G. De Smedt, H. Vanaken, M.P. Bouche, M. Peeters, et al. A pharmacokinetic study of etravirine (TMC125) co-administered with ranitidine and omeprazole in HIV-negative volunteers Br J Pharmacol 66 2008 508 516
-
(2008)
Br J Pharmacol
, vol.66
, pp. 508-516
-
-
Schöller-Gyüre, M.1
Kakuda, T.N.2
De Smedt, G.3
Vanaken, H.4
Bouche, M.P.5
Peeters, M.6
-
29
-
-
77957355346
-
TMC125 in combination with other medications: Summary of drug-drug interaction studies
-
Oral presentation PL5.2
-
T. Kakuda, M. Schöller-Gyüre, B. Woodfall, G. De Smedt, M. Peeters, K. Vandermeulen, et al. TMC125 in combination with other medications: summary of drug-drug interaction studies 8th International Congress on Drug Therapy in HIV Infection Glasgow. 12-16 November 2006 Oral presentation PL5.2
-
8th International Congress on Drug Therapy in HIV Infection Glasgow. 12-16 November 2006
-
-
Kakuda, T.1
Schöller-Gyüre, M.2
Woodfall, B.3
De Smedt, G.4
Peeters, M.5
Vandermeulen, K.6
|