Prediction of immunogenicity of therapeutic proteins: Validity of computational tools

BioDrugs

Volumn 24, Issue 1, 2010, Pages 1-8

  Bryson, Christine J ^a   Jones, Tim D ^a   Baker, Matthew P ^a  

^a Antitope Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; B CELL EPITOPE; B LYMPHOCYTE ANTIGEN; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN; RITUXIMAB; T CELL EPITOPE; T LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG; VACCINE;

AMINO ACID SEQUENCE; BINDING AFFINITY; CELL ASSAY; COMPLEX FORMATION; COMPUTATIONAL FLUID DYNAMICS; COMPUTER MODEL; COMPUTER PROGRAM; DATA BASE; DRUG DESIGN; HUMAN; IMMUNE SYSTEM; IMMUNIZATION; IMMUNOGENICITY; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOLECULE; PREDICTION; PRIORITY JOURNAL; PROTEIN CONFORMATION; REVIEW; SCREENING; T LYMPHOCYTE ACTIVATION; VALIDITY;

ANIMALS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; DATABASES, GENETIC; EPITOPES, T-LYMPHOCYTE; HUMANS; PROTEINS; REPRODUCIBILITY OF RESULTS;

EID: 75149152376     PISSN: 11738804     EISSN: 1179190X     Source Type: Journal    
DOI: 10.2165/11318560-000000000-00000     Document Type: Review

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