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Volumn 8, Issue 3, 2010, Pages 691-697

Preparation and biological evaluation of novel leucomycin analogs derived from nitroso Diels-Alder reactions

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-PROLIFERATIVE; BIOLOGICAL EVALUATION; BOND REDUCTIONS; CYCLOADDITION REACTION; CYCLOADDUCTS; CYTOTOXIC ACTIVITIES; DIELS-ALDER REACTION; MACROLIDES; NITROSO; STEREO-SELECTIVE;

EID: 75149152271     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b922450e     Document Type: Article
Times cited : (20)

References (29)
  • 24
  • 27
    • 75149197768 scopus 로고    scopus 로고
    • Chemical derivatization of macrolide-antibiotic leucomycin
    • HKI, Leibniz Institute for Natural Products Research and Infection Biology-Friedrich-Schiller-University, Germany
    • T. Zöllner, Chemical Derivatization of Macrolide-Antibiotic Leucomycin, HKI, PhD Dissertation, Leibniz Institute for Natural Products Research and Infection Biology-Friedrich-Schiller-University, Germany, 2008
    • (2008) PhD Dissertation
    • Zöllner, T.1
  • 28
    • 0025362839 scopus 로고
    • Crystal structures of the Haloarcula marismortui large ribosomal subunit complexed with the 16-membered macrolide antibiotics carbomycin A, spiramycin and tylosin show that the ethyladehyde substituent at the C6 position binds reversibly at the 50-S ribosomal subunit of the peptidyl transferase center, which blocks the elongation process during the peptide synthesis. See:
    • S. Cicchi A. Goti A. Brandi A. Guarna F. D. De Sarlos Tetrahedron Lett. 1990 31 3351
    • (1990) Tetrahedron Lett. , vol.31 , pp. 3351
    • Cicchi, S.1    Goti, A.2    Brandi, A.3    Guarna, A.4    De Sarlos, F.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.