miR-31: A master regulator of metastasis?

Future Oncology

Volumn 6, Issue 1, 2010, Pages 17-20

  Schmittgen, Thomas D ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Anoikis; Breast cancer; Metastasis; MicroRNA; miR 31

Indexed keywords

FRIZZLED PROTEIN; FRIZZLED PROTEIN 3; MASPIN; MATRIX METALLOPROTEINASE 16; MICRORNA; MICRORNA 31; NEUROSERPIN; RADIXIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TROPOMYOSIN; UNCLASSIFIED DRUG;

ANOIKIS; APOPTOSIS; BREAST CANCER; CANCER INHIBITION; CANCER SURVIVAL; CELL CYCLE REGULATION; CELL INVASION; CELL PROLIFERATION; CELL VIABILITY; GENE CONTROL; GENE OVEREXPRESSION; HUMAN; METASTASIS POTENTIAL; NONHUMAN; NOTE; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 75149149257     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.09.150     Document Type: Note

References (24)

1. Hurst DR, Edmonds MD, Welch DR: Metastamir: the field of metastasis-regulatory microRNA is spreading. Cancer Res. 69(19), 7495-7498 (2009).
2. Nicoloso MS, Spizzo R, Shimizu M, Rossi S, Calin GA: MicroRNAs - the micro steering wheel of tumour metastases. Nat. Rev. Cancer 9(4), 293-302 (2009).
3. Zhu S, Si ML, Wu H, Mo YY: MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem. 282(19), 14328-14336 (2007).
4. Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY: MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res. 18(3), 350-359 (2008).
5. Asangani IA, Rasheed SA, Nikolova DA et al.: MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27(15), 2128-2136 (2008).
6. Gabriely G, Wurdinger T, Kesari S et al.: MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol. Cell. Biol. 28(17), 5369-5380 (2008).
7. Ma L, Teruya-Feldstein J, Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449(7163), 682-688 (2007).
8. Gregory PA, Bracken CP, Bert AG, Goodall GJ: MicroRNAs as regulators of epithelial-mesenchymal transition. Cell Cycle 7(20), 3112-3118 (2008).
9. Valastyan S, Reinhardt F, Benaich N et al.: A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 137(6), 1032-1046 (2009).
10. Chan JA, Krichevsky AM, Kosik KS: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65(14), 6029-6033 (2005).
11. Lee EJ, Baek M, Gusev Y, Brackett DJ, Nuovo GJ, Schmittgen TD: Systematic evaluation of microRNA processing patterns in tissues, cell lines, and tumors. RNA 14(1), 35-42 (2007).
12. Kota J, Chivukula RR, O'Donnell KA et al.: Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137(6), 1005-1017 (2009).
13. Liu X, Chen Z, Yu J, Xia J, Zhou X: MicroRNA profiling and head and neck cancer. Comp. Funct. Genomics 837514 (2009).
14. Yan LX, Huang XF, Shao Q et al.: MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 14(11), 2348-2360 (2008).
15. Schafer A, Jung M, Mollenkopf HJ et al.: Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma. Int. J. Cancer (2009) (Epub ahead of print).
16. Zhang Y, Guo J, Li D et al.: Down-regulation of miR-31 expression in gastric cancer tissues and its clinical significance. Med. Oncol. (2009) (Epub ahead of print).
17. Guo J, Miao Y, Xiao B et al.: Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J. Gastroenterol. Hepatol. 24(4), 652-657 (2009).
18. Motoyama K, Inoue H, Takatsuno Y et al.: Over- and under-expressed microRNAs in human colorectal cancer. Int. J. Oncol. 34(4), 1069-1075 (2009).
19. Wang CJ, Zhou ZG, Wang L et al.: Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer. Dis. Markers 26(1), 27-34 (2009).
20. Slaby O, Svoboda M, Fabian P et al.: Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology 72(5-6), 397-402 (2007).
21. Bandres E, Cubedo E, Agirre X et al.: Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol. Cancer 5, 29 (2006).
22. Veerla S, Lindgren D, Kvist A et al.: MiRNA expression in urothelial carcinomas: important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31. Int. J. Cancer 124(9), 2236-2242 (2009).
23. Wong QW, Lung RW, Law PT et al.: MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1. Gastroenterology 135(1), 257-269 (2008).
24. Wong TS, Liu XB, Wong BY, Ng RW, Yuen AP, Wei WI: Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin. Cancer Res. 14(9), 2588-2592 (2008).