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Volumn 277, Issue 3, 2010, Pages 790-795

The bioactive dipeptide anserine is transported by human proton-coupled peptide transporters

Author keywords

Carnosine; Intestine; Kidney; PEPT1; PEPT2

Indexed keywords

ANSERINE; CARNOSINE; GLYCINE; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2;

EID: 75149146542     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07528.x     Document Type: Article
Times cited : (29)

References (25)
  • 1
    • 0014785883 scopus 로고
    • Carnosine and related substances in animal tissues
    • Crush KG (1970) Carnosine and related substances in animal tissues. Comp Biochem Physiol 34, 3 30.
    • (1970) Comp Biochem Physiol , vol.34 , pp. 3-30
    • Crush, K.G.1
  • 2
    • 64549097209 scopus 로고    scopus 로고
    • Intestinal absorption and blood clearance of l-histidine-related compounds after ingestion of anserine in humans and comparison to anserine-containing diets
    • Kubomura D, Matahira Y, Masui A Matsuda H (2009) Intestinal absorption and blood clearance of l-histidine-related compounds after ingestion of anserine in humans and comparison to anserine-containing diets. J Agric Food Chem 57, 1781 1785.
    • (2009) J Agric Food Chem , vol.57 , pp. 1781-1785
    • Kubomura, D.1    Matahira, Y.2    Masui, A.3    Matsuda, H.4
  • 3
    • 0027955233 scopus 로고
    • Biosynthesis of carnosine and related peptides by skeletal muscle cells in primary culture
    • Bauer K Schulz M (1994) Biosynthesis of carnosine and related peptides by skeletal muscle cells in primary culture. Eur J Biochem 219, 43 47. (Pubitemid 24053615)
    • (1994) European Journal of Biochemistry , vol.219 , Issue.1-2 , pp. 43-47
    • Bauer, K.1    Schulz, M.2
  • 4
    • 1442269395 scopus 로고
    • Enzymatic synthesis of anserine in skeletal muscle by N-methylation of carnosine
    • McManus R (1962) Enzymatic synthesis of anserine in skeletal muscle by N-methylation of carnosine. J Biol Chem 237, 1207 1211.
    • (1962) J Biol Chem , vol.237 , pp. 1207-1211
    • McManus, R.1
  • 5
    • 0024788706 scopus 로고
    • Carnosine, homocarnosine and anserine: Could they act as antioxidants in vivo?
    • Aruoma OI, Laughton MJ Halliwell B (1989) Carnosine, homocarnosine and anserine: could they act as antioxidants in vivo? Biochem J 264, 863 869.
    • (1989) Biochem J , vol.264 , pp. 863-869
    • Aruoma, O.I.1    Laughton, M.J.2    Halliwell, B.3
  • 6
    • 24344449088 scopus 로고    scopus 로고
    • Carnosine and anserine act as effective transglycating agents in decomposition of aldose-derived Schiff bases
    • Szwergold BS (2005) Carnosine and anserine act as effective transglycating agents in decomposition of aldose-derived Schiff bases. Biochem Biophys Res Commun 336, 36 41.
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 36-41
    • Szwergold, B.S.1
  • 7
    • 0028185906 scopus 로고
    • Endogenous skeletal muscle antioxidants
    • Chan KM Decker EA (1994) Endogenous skeletal muscle antioxidants. Crit Rev Food Sci Nutr 34, 403 426.
    • (1994) Crit Rev Food Sci Nutr , vol.34 , pp. 403-426
    • Chan, K.M.1    Decker, E.A.2
  • 8
    • 0031698178 scopus 로고    scopus 로고
    • Carnosine and other imidazole-containing compounds enhance the postdenervation depolarization of the rat diaphragm fibres
    • Urazaev AKh, Naumenko NV, Nikolsky EE Vyskocil F (1998) Carnosine and other imidazole-containing compounds enhance the postdenervation depolarization of the rat diaphragm fibres. Physiol Res 47, 291 295.
    • (1998) Physiol Res , vol.47 , pp. 291-295
    • Akh, U.1    Naumenko, N.V.2    Nikolsky, E.E.3    Vyskocil, F.4
  • 11
    • 2342644210 scopus 로고    scopus 로고
    • Molecular and integrative physiology of intestinal peptide transport
    • DOI 10.1146/annurev.physiol.66.032102.144149
    • Daniel H (2004) Molecular and integrative physiology of intestinal peptide transport. Annu Rev Physiol 66, 361 384. (Pubitemid 40614448)
    • (2004) Annual Review of Physiology , vol.66 , pp. 361-384
    • Daniel, H.1
  • 12
    • 68149161029 scopus 로고    scopus 로고
    • Transport of drugs by proton-coupled peptide transporters: Pearls and pitfalls
    • Brandsch M (2009) Transport of drugs by proton-coupled peptide transporters: pearls and pitfalls. Expert Opin Drug Metab Toxicol 5, 887 905.
    • (2009) Expert Opin Drug Metab Toxicol , vol.5 , pp. 887-905
    • Brandsch, M.1
  • 13
    • 0016213534 scopus 로고
    • Evidence for active transport of the dipeptide carnosine (β-alanyl-l-histidine) by hamster jejunum in vitro
    • Matthews DM, Addison JM Burston D (1974) Evidence for active transport of the dipeptide carnosine (β-alanyl-l-histidine) by hamster jejunum in vitro. Clin Sci Mol Med 46, 693 705.
    • (1974) Clin Sci Mol Med , vol.46 , pp. 693-705
    • Matthews, D.M.1    Addison, J.M.2    Burston, D.3
  • 14
    • 0021025978 scopus 로고
    • Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with l-carnosine and glycyl-l-proline
    • Ganapathy V Leibach FH (1983) Role of pH gradient and membrane potential in dipeptide transport in intestinal and renal brush-border membrane vesicles from the rabbit. Studies with l-carnosine and glycyl-l-proline. J Biol Chem 258, 14189 14192.
    • (1983) J Biol Chem , vol.258 , pp. 14189-14192
    • Ganapathy, V.1    Leibach, F.H.2
  • 18
    • 2442688922 scopus 로고    scopus 로고
    • +/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells
    • +/peptide cotransporters PEPT1 and PEPT2 in intestinal and renal epithelial cells. Eur J Biochem 271, 2012 2017.
    • (2004) Eur J Biochem , vol.271 , pp. 2012-2017
    • Neumann, J.1    Bruch, M.2    Gebauer, S.3    Brandsch, M.4
  • 19
    • 0015861774 scopus 로고
    • i) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
    • i) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22, 3099 3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.H.2
  • 21
    • 0033671162 scopus 로고    scopus 로고
    • Hydrolysis of carnosine and related compounds by mammalian carnosinases
    • Pegova A, Abe H Boldyrev A (2000) Hydrolysis of carnosine and related compounds by mammalian carnosinases. Comp Biochem Physiol B 127, 443 446.
    • (2000) Comp Biochem Physiol B , vol.127 , pp. 443-446
    • Pegova, A.1    Abe, H.2    Boldyrev, A.3
  • 22
    • 65549144098 scopus 로고    scopus 로고
    • The role of N-glycosylation in transport function and surface targeting of the human solute carrier PAT1
    • Dorn M, Jaehme M, Weiwad M, Markwardt F, Rudolph R, Brandsch M Bosse-Doenecke E (2009) The role of N-glycosylation in transport function and surface targeting of the human solute carrier PAT1. FEBS Lett 583, 1631 1636.
    • (2009) FEBS Lett , vol.583 , pp. 1631-1636
    • Dorn, M.1    Jaehme, M.2    Weiwad, M.3    Markwardt, F.4    Rudolph, R.5    Brandsch, M.6    Bosse-Doenecke, E.7
  • 23
    • 34047233727 scopus 로고    scopus 로고
    • Kinetics of P2X7 receptor-operated single channel currents
    • Riedel T, Lozinsky I, Schmalzing G Markwardt F (2007) Kinetics of P2X7 receptor-operated single channel currents. Biophys J 92, 2377 2391.
    • (2007) Biophys J , vol.92 , pp. 2377-2391
    • Riedel, T.1    Lozinsky, I.2    Schmalzing, G.3    Markwardt, F.4
  • 25
    • 0031788293 scopus 로고    scopus 로고
    • Drug-dependent ion channel gating by application of concentration jumps using U-tube technique
    • Bretschneider F Markwardt F (1999) Drug-dependent ion channel gating by application of concentration jumps using U-tube technique. Methods Enzymol 294, 180 189.
    • (1999) Methods Enzymol , vol.294 , pp. 180-189
    • Bretschneider, F.1    Markwardt, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.