Binding conformation and kinetics of two pheromone-binding proteins from the gypsy moth Lymantria dispar with biological and nonbiological ligands

Biochemistry

Volumn 49, Issue 4, 2010, Pages 793-801

  Gong, Yongmei ^a   Tang, Hao ^b   Bohne, Cornelia ^b   Plettner, Erika ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

^b UNIVERSITY OF VICTORIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING CONFORMATIONS; BIOLOGICAL LIGANDS; C-TERMINAL PEPTIDES; CONFORMATIONAL CHANGE; DOWNSTREAM COMPONENTS; ELECTRONIC ENVIRONMENTS; GYPSY MOTHS; HYDROPHOBIC ENVIRONMENT; KINETIC STEPS; LYMANTRIA DISPAR; NAPHTHYLAMINE; OLFACTORY SYSTEMS; PHEROMONE-BINDING PROTEINS; SENSORY NEURONS; SIGNAL MOLECULES; STOPPED-FLOW KINETICS; TRYPTOPHAN FLUORESCENCE; WORK SUPPORT;

AMINO ACIDS; CONFORMATIONS; NEURONS; PEPTIDES;

LIGANDS;

8 ANILINO 1 NAPHTHALENESULFONIC ACID; BINDING PROTEIN; LIGAND; PHEROMONE; PHEROMONE BINDING PROTEIN 1; PHEROMONE BINDING PROTEIN 2; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COLLISIONALLY ACTIVATED DISSOCIATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIFFUSION; FLOW KINETICS; FLUORESCENCE; GYPSY MOTH; HYDROPHOBICITY; LIGAND BINDING; NONHUMAN; NONPHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; STEREOSPECIFICITY;

ANIMALS; CARRIER PROTEINS; INSECT PROTEINS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOTHS; PHEROMONES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

HEXAPODA; LYMANTRIA; LYMANTRIA DISPAR;

EID: 75149136643     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901145a     Document Type: Article

References (30)

1. Pesenti, M. E., Spinelli, S., Bezirard, V., Briand, L., Pernollet, J. C., Tegoni, M., and Cambillau, C. (2008) Structural basis of the honey bee PBP pheromone and pH-induced conformational change. J. Mol. Biol. 380, 158-169.
2. Damberger, F. F., Ishida, Y., Leal, W. S., and Wuethrich, K. (2007) Structural basis of ligand binding and release in insect pheromonebinding proteins: NMR structure of Antheraea polyphemus PBP1 at pH 4.5. J. Mol. Biol. 373, 811-819.
3. Lautenschlager, C., Leal, W. S., and Clardy, J. (2005) Coil-to-helix transition and ligand release of Bombyx mori pheromone-binding protein. Biochem. Biophys. Res. Commun. 335, 1044-1050.
4. Wojtasek, H., and Leal, W. S. (1999) Conformational change in the pheromone-binding protein from Bombyx mori induced by pH and by interaction with membranes. J. Biol. Chem. 274, 30950-30956.
5. Laughlin, J. D., Ha, T. S., Jones, D. N. M., and Smith, D. P. (2008) Activation of pheromone-sensitive neurons is mediated by conformational activation of pheromone-binding protein. Cell 133, 1255-1265.
6. Krieger, J., and Breer, H. (1999) Olfactory reception in invertebrates. Science 286, 720-723.
7. Honson, N., Johnson, M. A., Oliver, J. E., Prestwich, G. D., and Plettner, E. (2003) Structure-activity studies with pheromone-binding proteins of the gypsy moth, Lymantria dispar. Chem. Senses 28, 479-489.
8. Lautenschlager, C., Leal, W. S., and Clardy, J. (2007) Bombyx mori pheromone-binding protein binding nonpheromone ligands: Implications for pheromone recognition. Structure 15, 1148-1154.
9. Sandler, B. H., Nikonova, L., Leal, W. S., and Clardy, J. (2000) Sexual attraction in the silkworm moth: Structure of the pheromone-bindingprotein- bombykol complex. Chem. Biol. 7, 143-151.
10. Kruse, S. W., Zhao, R., Smith, D. P., and Jones, D. N. M. (2003) Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster. Nat. Struct. Biol. 10, 694-700.
11. Lartigue, A., Gruez, A., Spinelli, S., Riviere, S., Brossut, R., Tegoni, M., and Cambillau, C. (2003) The crystal structure of a cockroach pheromone-binding protein suggests a new ligand binding and release mechanism. J. Biol. Chem. 278, 30213-30218.
12. Gong, Y., Pace, T. C. S., Castillo, C., Bohne, C., O'Neill, M. A., and Plettner, E. (2009) Ligand-interaction kinetics of the pheromone-binding protein from the gypsy moth, L. dispar: Insights into the mechanism of binding and release. Chem. Biol. 16, 162-172.
13. Plettner, E., Lazar, J., Prestwich, E. G., and Prestwich, G. D. (2000) Discrimination of pheromone enantiomers by two pheromone binding proteins from the gypsy moth Lymantria dispar. Biochemistry 39, 8953-8962.
14. Lartigue, A., Gruez, A., Briand, L., Blon, F., Bezirard, V., Walsh, M., Pernollet, J. C., Tegoni, M., and Cambillau, C. (2004) Sulfur single-wavelength anomalous diffraction crystal structure of a pheromone-binding protein from the honeybee Apis mellifera L. J. Biol. Chem. 279, 4459-4464.
15. Mohanty, S., Zubkov, S., and Gronenborn, A. M. (2004) The solution NMR structure of Antheraea polyphemus PBP provides new insight into pheromone recognition by pheromone-binding proteins. J. Mol. Biol. 337, 443-451.
16. Wogulis, M., Morgan, T., Ishida, Y., Leal, W. S., and Wilson, D. K. (2006) The crystal structure of an odorant binding protein from Anopheles gambiae: Evidence for a common ligand release mechanism. Biochem. Biophys. Res. Commun. 339, 157-164.
17. Venyaminov, S. Y., and Vassilenko, K. S. (1994) Determination of protein tertiary structure class from circular-dichroism spectra. Anal. Biochem. 222, 176-184.
18. Fersht, A. (1999) Structure and mechanism in protein science:Aguide to enzyme catalysis and protein folding, W. H. Freeman, New York.
19. Birks, J. B. (1970) Photophysics of aromatic molecules, Wiley-Interscience, New York.
20. Eftink, M. R., and Ghiron, C. A. (1976) Exposure of tryptophanyl residues in proteins - Quantitative determination by fluorescence quenching studies. Biochemistry 15, 672-680.
21. Lehrer, S. S. (1971) Solute perturbation of protein fluorescence - Quenching of tryptophyl fluorescence of model compounds and of lysozyme by iodide ion. Biochemistry 10, 3254-3263.
22. Bette, S., Breer, H., and Krieger, J. (2002) Probing a pheromone binding protein of the silkmoth Antheraea polyphemus by endogenous tryptophan fluorescence. Insect Biochem. Mol. Biol. 32, 241-246.
23. Leal, W. S., Chen, A. M., Ishida, Y., Chiang, V. P., Erickson, M. L., Morgan, T. I., and Tsuruda, J. M. (2005) Kinetics and molecular properties of pheromone binding and release. Proc. Natl. Acad. Sci. U.S.A. 102, 5386-5391.
24. Kowcun, A., Honson, N., and Plettner, E. (2001) Olfaction in the gypsy moth, Lymantria dispar - Effect of pH, ionic strength, and reductants on pheromone transport by pheromone-binding proteins. J. Biol. Chem. 276, 44770-44776.
25. Isin, E. M., and Guengerich, F. P. (2006) Kinetics and thermo-dynamics of ligand binding by cytochrome P450 3A4. J. Biol. Chem. 281, 9127-9136.
26. Honson, N. S., and Plettner, E. (2006) Disulfide connectivity and reduction in pheromone-binding proteins of the gypsy moth, Lymantria dispar. Naturwissenschaften 93, 267-277.
27. Vogt, R. G., Kohne, A. C., Dubnau, J. T., and Prestwich, G. D. (1989) Expression of pheromone binding-proteins during antennal development in the gypsy moth Lymantria dispar. J. Neurosci. 9, 3332-3346.
28. Thode, A. B., Kruse, S. W., Nix, J. C., and Jones, D. N. M. (2008) The role of multiple hydrogen-bonding groups in specific alcohol binding sites in proteins: Insights from structural studies of LUSH. J. Mol. Biol. 376, 1360-1376.
29. Grosse-Wilde, E., Svatos, A., and Krieger, J. (2006) A pheromone-binding protein mediates the bombykol-induced activation of a pheromone receptor in vitro. Chem. Senses 31, 547-555.
30. Pophof, B. (2002) Moth pheromone binding proteins contribute to the excitation of olfactory receptor cells. Naturwissenschaften 89, 515-518.