HMG-CoA reductase inhibition causes increased necrosis and apoptosis in an in vivo mouse glioblastoma multiforme model

Anticancer Research

Volumn 29, Issue 12, 2009, Pages 4901-4908

  Bababeygy, Simon R ^a,b   Polevaya, Nika V ^a   Youssef, Sawsan ^b   Sun, Amy ^a   Xiong, Anming ^a   Prugpichailers, Tiffany ^a   Veeravagu, Anand ^a   Hou, Lewis C ^a   Steinman, Lawrence ^b   Tse, Victor ^a,c  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Kaiser Neurosurgery   (United States)

Author keywords

Apoptosis; Glioblastoma; HMG CoA reductase; Necrosis; Pericytes; Simvastatin

Indexed keywords

SIMVASTATIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL STRUCTURE; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE EXACERBATION; DRUG DOSE COMPARISON; DRUG MEGADOSE; GLIOBLASTOMA; HUMAN; HUMAN CELL; LOW DRUG DOSE; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; TUMOR NECROSIS; TUMOR VASCULARIZATION; TUMOR VOLUME;

ACYL COENZYME A; ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; GLIOBLASTOMA; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNOENZYME TECHNIQUES; MICE; MICE, INBRED C57BL; NECROSIS; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PHYSIOLOGIC; SIMVASTATIN;

EID: 75149124370     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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