Outcomes of matched sibling and alternative donor stem cell transplantation for 26 children with severe aplastic anemia

International Journal of Hematology

Volumn 91, Issue 1, 2010, Pages 54-60

  Hsieh, Ming Yun ^a   Chiou, Tzeon Jye ^b   Hung, Giun Yi ^b   Yen, Hsiu Ju ^b  

^a FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Alternative donor; Hematopoietic stem cell transplantation; Severe aplastic anemia; Sibling donor

Indexed keywords

ADOLESCENT; APLASTIC ANEMIA; ARTICLE; CHILD; CLINICAL ARTICLE; DONOR; FEMALE; GRAFT FAILURE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MALE; PRESCHOOL CHILD; SCHOOL CHILD; STEM CELL TRANSPLANTATION; SURVIVAL RATE; SURVIVAL TIME;

ADOLESCENT; ANEMIA, APLASTIC; CHILD; CHILD, PRESCHOOL; FEMALE; GRAFT SURVIVAL; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; HUMANS; MALE; PROGNOSIS; SEVERITY OF ILLNESS INDEX; SIBLINGS; TISSUE DONORS; TREATMENT OUTCOME;

EID: 75049085182     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12185-009-0465-4     Document Type: Article

References (27)

1. BM Camitta ED Thomas DG Nathan RP Gale KJ Kopecky JM Rappeport, et al. 1979 A prospective study of androgens and bone marrow transplantation for treatment of severe aplitic anemia Blood 53 504 514 1:STN:280: DyaE1M7gsVamug%3D%3D 32941
2. ED Thomas R Storb A Fefer SJ Slichter JI Bryant CD Buckner, et al. 1972 Aplastic anemia treated by bone marrow transplantation Lancet 1 284 289 1:STN:280:DyaE387gtFygtw%3D%3D 4109931
3. S Kojima K Horibe J Inaba A Yoshimi Y Takahashi K Kudo, et al. 2000 Long-term outcome of acquired aplastic anaemia in children: comparison between immunosuppressive therapy and bone marrow transplantation Br J Haematol 111 321 328 10.1046/j.1365-2141.2000.02289.x 1:STN:280:DC%2BD3M%2FltFagsg%3D%3D 11091219 (Pubitemid 30832469)
4. JK Davies EC Guinan 2007 An update on the management of severe idiopathic aplastic anaemia in children Br J Haematol 136 549 564 10.1111/j.1365-2141. 2006.06461.x 1:CAS:528:DC%2BD2sXjtlKjsLo%3D 17214739 (Pubitemid 46148192)
5. N Bunin R Aplenc R Iannone A Leahey S Grupp D Monos, et al. 2005 Unrelated donor bone marrow transplantation for children with severe aplastic anemia: minimal GVHD and durable engraftment with partial T cell depletion Bone Marrow Transplant 35 369 373 10.1038/sj.bmt.1704803 1:CAS:528: DC%2BD2MXhtFWnsLs%3D 15640818 (Pubitemid 40309482)
6. ED Perez-Albuerne M Eapen J Klein TJ Gross JM Lipton KS Baker, et al. 2008 Outcome of unrelated donor stem cell transplantation for children with severe aplastic anemia Br J Haematol 141 216 223 10.1111/j.1365-2141.2008.07030. x 18307564
7. AA Kennedy-Nasser KS Leung A Mahajan HL Weiss JA Arce S Gottschalk, et al. 2006 Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia Biol Blood Marrow Transplant 12 1277 1284 10.1016/j.bbmt.2006.07.011 17162209 (Pubitemid 44858261)
8. ER Lawlor RA Anderson JH Davis CJ Fryer SL Pritchard PC Rogers, et al. 1997 Immunosuppressive therapy: a potential alternative to bone marrow transplantation as initial therapy for acquired severe aplastic anemia in childhood? J Pediatr Hematol Oncol 19 115 123 10.1097/00043426-199703000-00004 1:STN:280:DyaK2s3ptlyntA%3D%3D 9149740 (Pubitemid 27200553)
9. Bacigalupo A, Bruno B, Saracco P, Di Bona E, Locasciulli A, Locatelli F, et al. Antilymphocyte globulin, cyclosporine, prednisolone, and granulocyte colony-stimulating factor for severe aplastic anemia: an update of the GITMO/EBMT study on 100 patients. European Group for Blood and Marrow Transplantation (EBMT) Working Party on Severe Aplastic Anemia and the Gruppo Italiano Trapianti di Midolio Osseo (GITMO). Blood 2000;95:1931-4.
10. Kojima S, Ohara A, Tsuchida M, Kudoh T, Hanada R, Okimoto Y, et al. Japan Childhood Aplastic Anemia Study Group. Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children. Blood 2002;100:786-90.
11. TD Lee 2002 Marrow donor registry and cord blood bank in Taiwan Int J Hematol 76 312 314 10.1007/BF03165271 12430871
12. D Przepiorka D Weisdorf P Martin HG Klingemann P Beatty J Hows, et al. 1995 1994 consensus conference on acute GVHD grading Bone Marrow Transplant 15 825 828 1:STN:280:DyaK28%2Fot1Ojtw%3D%3D 7581076
13. HM Shulman KM Sullivan PL Weiden GB McDonald GE Striker GE Sale, et al. 1980 Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients Am J Med 69 204 217 10.1016/0002-9343(80)90380-0 1:STN:280:DyaL3c3mtlSksg%3D%3D 6996481 (Pubitemid 10036817)
14. CH Tzeng JY Lyou JS Lin YR Chen HY Hu CH Yung, et al. 1998 Allogeneic peripheral blood stem cell transplantation and early detection of donor engraftment by polymerase chain reaction J Formos Med Assoc 97 252 260 1:CAS:528:DyaK1cXislansLs%3D 9585676
15. Locasciulli A, Oneto R, Bacigalupo A, Socié G, Korthof E, Bekassy A, et al. Severe Aplastic Anemia Working Party of the European Blood and Marrow Transplant Group. Outcome of patients with acquired aplastic anemia given first line bone marrow transplantation or immunosuppressive treatment in the last decade: a report from the European Group for Blood and Marrow Transplantation (EBMT). Haematologica 2007;92:11-8.
16. C Kahl W Leisenring HJ Deeg TR Chauncey ME Flowers PJ Martin, et al. 2005 Cyclophosphamide and antithymocyte globulin as a conditioning regimen for allogeneic marrow transplantation in patients with aplastic anaemia: a long-term follow-up Br J Haematol 130 747 751 10.1111/j.1365-2141.2005.05667.x 1:CAS:528:DC%2BD2MXhtVyhsbnL 16115132 (Pubitemid 43906647)
17. R Storb KG Blume MR O'Donnell T Chauncey SJ Forman HJ Deeg, et al. 2001 Cyclophosphamide and antithymocyte globulin to condition patients with aplastic anemia for allogeneic marrow transplantations: the experience in four centers Biol Blood Marrow Transplant 7 39 44 10.1053/bbmt.2001.v7.pm11215697 1:STN:280:DC%2BD3M3jtlWrtg%3D%3D 11215697
18. SA Feig R Champlin E Arenson C Yale W Ho A Tesler, et al. 1983 Improved survival following bone marrow transplantation for aplastic anaemia Br J Haematol 54 509 517 10.1111/j.1365-2141.1983.tb02129.x 1:STN:280: DyaL3s3lslSksQ%3D%3D 6347239
19. HJ Deeg C Anasetti E Petersdorf R Storb K Doney JA Hansen, et al. 1994 Cyclophosphamide plus ATG conditioning is insufficient for sustained hematopoietic reconstitution in patients with severe aplastic anemia transplanted with marrow from HLA-A, B, DRB matched unrelated donors Blood 83 3417 3418 1:STN:280:DyaK2c3ltV2gsg%3D%3D 8193380
20. HJ Deeg G Socié G Schoch M Henry-Amar RP Witherspoon A Devergie, et al. 1996 Malignancies after marrow transplantation for aplastic anemia and fanconi anemia: a joint Seattle and Paris analysis of results in 700 patients Blood 87 386 392 1:CAS:528:DyaK28Xit1Sgsw%3D%3D 8547667
21. HJ Deeg M O'Donnell J Tolar R Agarwal RE Harris SA Feig, et al. 2006 Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy Blood 108 1485 1491 10.1182/blood-2006-03-005041 1:CAS:528:DC%2BD28Xpt1Slt70%3D 16684959 (Pubitemid 44316112)
22. Bacigalupo A, Locatelli F, Lanino E, Marsh J, Socié G, Maury S, et al. Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow Transplantation. Fludarabine, cyclophosphamide and anti-thymocyte globulin for alternative donor transplants in acquired severe aplastic anemia: a report from the EBMT-SAA Working Party. Bone Marrow Transplant. 2005;36:947-50.
23. J Inagaki Y Nagatoshi Y Kawano Y Saito D Takahashi J Nagayama, et al. 2007 Bone marrow transplantation in children with severe aplastic anemia using a conditioning regimen containing 3 Gy of total body irradiation, cyclophosphamide with or without antithymocyte globulin Pediatr Transplant 11 180 186 10.1111/j.1399-3046.2006.00640.x 17300498 (Pubitemid 46174990)
24. JR Passweg WS Pérez M Eapen BM Camitta E Gluckman W Hinterberger, et al. 2006 Bone marrow transplants from mismatched related and unrelated donors for severe aplastic anemia Bone Marrow Transplant 37 641 649 10.1038/sj.bmt.1705299 1:STN:280:DC%2BD287mt1elsg%3D%3D 16489361
25. G Socié JV Stone JR Wingard D Weisdorf PJ Henslee-Downey C Bredeson, et al. 1999 Long-term survival and late deaths after allogeneic bone marrow transplantation. Late Effects Working Committee of the International Bone Marrow Transplant Registry N Engl J Med 341 14 21 10.1056/NEJM199907013410103 10387937 (Pubitemid 29293715)
26. S Kojima T Matsuyama S Kato H Kigasawa R Kobayashi A Kikuta, et al. 2002 Outcome of 154 patients with severe aplastic anemia who received transplants from unrelated donors: the Japan Marrow Donor Program Blood 100 799 803 10.1182/blood.V100.3.799 1:CAS:528:DC%2BD38XlvVClt78%3D 12130489 (Pubitemid 34832604)
27. Maury S, Balère-Appert ML, Chir Z, Boiron JM, Galambrun C, Yakouben K, et al. French Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC). Unrelated stem cell transplantation for severe acquired aplastic anemia: improved outcome in the era of high-resolution HLA matching between donor and recipient. Haematologica 2007;92:589-96.