Withania somnifera prevents morphine withdrawal-induced decrease in spine density in nucleus accumbens shell of rats: A confocal laser scanning microscopy study

Neurotoxicity Research

Volumn 16, Issue 4, 2009, Pages 343-355

  Kasture, Sanjay ^a,b   Vinci, Stefania ^a   Ibba, Federico ^a   Puddu, Alessandro ^c   Marongiu, Mara ^c   Murali, Balasubramanian ^d   Pisanu, Augusta ^a   Lecca, Daniele ^a,f   Zernig, Gerald ^e   Acquas, Elio ^a,f  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b MGV's Pharmacy College   (India)

^c Istituto di Neurogenetica e Neurofarmacologia CNR   (Italy)

^d Natural Remedies Private Limited   (India)

^e INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^f INN National Institute of Neuroscience   (Italy)

Author keywords

Medium spiny neurons; Nucleus accumbens shell; Opiate withdrawal; Spine density; Withania somnifera

Indexed keywords

MORPHINE; WITHANIA SOMNIFERA EXTRACT; NALTREXONE; NARCOTIC ANTAGONIST; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL DENSITY; CHRONIC DRUG ADMINISTRATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DENDRITIC SPINE; DISEASE SEVERITY; DOPAMINERGIC NERVE CELL; GOLGI STAIN; MALE; NEUROIMAGING; NEUROPATHOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PTOSIS; RAT; WITHANIA SOMNIFERA; WITHDRAWAL SYNDROME; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; BLOOD; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; DISEASE MODEL; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHODOLOGY; MORPHINE ADDICTION; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYTOTHERAPY; SILVER STAINING; SPRAGUE DAWLEY RAT; TIME; ULTRASTRUCTURE; WITHANIA;

ANIMALIA; RATTUS; WITHANIA SOMNIFERA;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; MALE; MICROSCOPY, CONFOCAL; MORPHINE; MORPHINE DEPENDENCE; NALTREXONE; NARCOTIC ANTAGONISTS; NEURONS; NUCLEUS ACCUMBENS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SILVER STAINING; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS; WITHANIA;

EID: 74949136639     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12640-009-9069-2     Document Type: Article

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