Mucoadhesive liposomes as ocular delivery system: Physical, microbiological, and in vivo assessment

Drug Development and Industrial Pharmacy

Volumn 36, Issue 1, 2010, Pages 108-118

  Mehanna, Mohammed M ^a   Elmaradny, Hoda A ^a   Samaha, Magda W ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Chitosan coat; Chitosomes; Ciprofloxacin HCl; Corneal permeation; In vivo model; Liposomes; Ocular delivery

Indexed keywords

CHITOSAN; CHITOSOME; CHOLESTEROL; CIPROFLOXACIN; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BIOCOMPATIBILITY; CONJUNCTIVITIS; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CORNEA PERMEABILITY; DIFFUSION; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG PENETRATION; DRUG SCREENING; EVAPORATION; EXPERIMENTAL RABBIT; FEMALE; MALE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; MUCOADHESION; NONHUMAN; PARTICLE SIZE; PSEUDOMONAS AERUGINOSA; SINGLE DRUG DOSE; STAPHYLOCOCCUS AUREUS;

ADHESIVENESS; ADMINISTRATION, OPHTHALMIC; ANIMALS; ANTI-BACTERIAL AGENTS; CHITOSAN; CIPROFLOXACIN; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; LIPOSOMES; MALE; MICROBIAL SENSITIVITY TESTS; MOLECULAR WEIGHT; PERMEABILITY; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; RABBITS; RHEOLOGY; TIME FACTORS;

EID: 74949134210     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639040903099751     Document Type: Article

References (37)

1. Robinson JR, Mlynek GM. (1995). Bioadhesive and phase-change polymers for ocular drug delivery. Adv Drug Deliv Rev, 16:45-50.
2. Kaur IP, Kanwar M. (2002). Ocular preparations: The formulation approach. Drug Dev Ind Pharm, 28:473-493
3. Motwani SL, Chopra S, Talegaonkar S, Kohli K, Ahmed FJ, Khar RK. (2008). Chitosan-sodium alginate nanoparticles as submicroscopic reservoirs of ocular delivery: formulation, optimisation and in vitro characterisation. Eur J Pharm Biopharm, 68:513-525
4. Sahoo SK, Dilnawaz F, Krishnakumar S. (2008). Nanotechnology in ocular drug delivery. Drug Discov Today, 13:144-151
5. Dumitriu S, Chornet E. (1998). Inclusion and release of proteins from polysaccharide-based polyion complexes. Adv Drug Deliv Rev, 31:223-246
6. Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. (2004). Recent advances on chitosan-based micro- and nanoparticles in drug delivery. J Control Release, 100:5-28.
7. Takeuchi H, Matsui Y, Yamamoto H, Kawashima Y. (2003). Mucoadhesive properties of carbopol or chitosan-coated liposomes and their effectiveness in the oral administration of calcitonin to rats. J Control Release, 86:235-242
8. Takeuchi H, Matsui Y, Sugihara H, Yamamoto H, Kawashima Y. (2005). Effectiveness of submicron-sized, chitosan-coated liposomes in oral administration of peptide drugs. Int J Pharm, 303:160-170
9. Drulis-Kawa Z, Gubernator J, Dorotkiewicz-jach A, Doroszkiewicz W, Kozubek A. (2006). A comparison of the in vitro antimicrobial activity of liposomes containing meropenem and gentamicin. Cell Mol Biol Lett, 11:360-375 (Pubitemid 44492467)
10. Pasquardini L, Lunelli L, Vanzetti L, Anderle M, Pederzolli C. (2008). Immobilization of cationic rifampicin-loaded liposomes on polystyrene for drug-delivery applications. Colloids Surf B: Biointerfaces, 62:265-272
11. Szoka F, Papahadjopoulos D. (1978). Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse phase evaporation. Biochemistry, 75:4194-4198
12. Mehanna MM, Elmaradny HA, Samaha MW. (2009). Ciprofloxacin liposomes as vesicular reservoirs for ocular delivery: Formulation, optimization and in vitro characterization. Drug Dev Ind Pharm, 35:583-593
13. Takeuchi H, Yamamoto H, Niwa T, Hino T, Kawashima Y. (1996). Enternal absorption of insulin in rats from mucoadhesive chitosan-coated liposomes. Pharm Res, 13:896-901.
14. Foco A, Gasperlin M, Kristl J. (2005). Investigation of liposomes as carriers of sodium ascorbyl phosphate for cutaneous photoprotection. Int J Pharm, 291:21-29
15. Trotta M, Peira E, Debernardi F, Gallarate M. (2002). Elastic liposomes for skin delivery of dipotassium glycyrrhizinate. Int J Pharm, 241:319-327
16. Guo J, Ping Q, Jiang G, Huang L, Tong Y. (2003). Chitosancoated liposomes: Characterization and interaction with leuprolide. Int J Pharm, 260:167-173
17. Maffei P, Lombardi Borgia S, Sforzini A, Bergamante V, Ceschel GC. (2004). Mucoadhesive tablets for buccal administration containing sodium nimesulide. Drug Deliv, 11:225-230
18. Aggarwal D, Garg A, Kaur IP. (2004). Development of a topical niosomal preparation of acetazolamide: Preparation and evaluation. J Pharm Pharmacol, 56:1509-1517
19. Anand BS, Mitra AK. (2002). Mechanism of corneal permeation of L-valyl ester of acyclovir: Targeting the oligopeptide transporter on the rabbit cornea. Pharm Res, 19:1194-1202
20. Koru O, Ozyurt M. (2008). Determination of antimicrobial susceptibilities of clinically isolated anaerobic bacteria by E-test, ATB-ANA and agar dilution. Anaerobe, 14:161-165
21. Charoo NA, Kohli K, Ali A. (2003). Preparation of in situforming ophthalmic gels of ciprofloxacin hydrochloride for the treatment of bacterial conjunctivitis: In vitro and in vivo studies. J Pharm Sci, 92:407-410
22. Owen GR, Brooks AC, James O, Robertson SM. (2007). A novel in vivo rabbit model that mimics human dosing to determine the distribution of antibiotics in ocular tissues. J Ocul Pharmacol Ther, 23:335-342
23. Filipovic-Grcic J, Skalko-Basnet N, Jalsenjak I. (2001). Mucoadhesive chitosan-coated liposomes: Characteristics and stability. J Microencapsul, 18:3-12.
24. Gonzalez-Rodriguez ML, Barros LB, Palma J, Gonzalez- Rodriguez PL, Rabasco AM. (2007). Application of statistical experimental design to study the formulation variables influencing the coating process of lidocaine liposomes. Int J Pharm, 337:336-345
25. Henriksen I, Smistad G, Kanlsen J. (1994). Interactions between liposome and chitosan. Int J Pharm, 101:227-236
26. Henriksen I, Vagen SR, Sande SA, Smistad G, Karlsen J. (1997). Interaction between liposomes and chitosan II: Effect of selected parameters on aggregation and leakage. Int J Pharm, 146:193-204.
27. Lo Y. Rahman Y. (1995). Protein location in liposomes, a drug carrier: A prediction by differential scanning calorimetry. J Pharm Sci, 84:805-813
28. Ramanathan S. Block LH. (2001). The use of chitosan gels as matrices for electrically modulated drug delivery. J Control Release, 70:109-123
29. Chen RH, Win HP, Fang HJ. (2001). Vesicle size, size distribution, stability, and rheological properties of liposomes coated with water-soluble chitosans of different molecular weights and concentrations. J Lipo Res, 11:211-228
30. Bochot A, Fattal E, Grossiord JL, Puisieux F, Couvreur P. (1998). Characterization of a new ocular delivery system based on a dispersion of liposomes in a thermosensitive gel. Int J Pharm, 162:119-127 (Pubitemid 28166097)
31. Srividya B, Cardoza RM, Amin PD. (2001). Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system. J Control Release, 73:205-211
32. Dhoot NO, Wheatley MA. (2003). Microencapsulated liposomes in controlled drug delivery: Strategies to modulate drug release and eliminate the burst effect. J Pharm Sci, 92:679-689
33. Kupferman A, Ryan WJJ, Leibowitz HM. (1981). Prolongation of antiinflammatory effect of prednisolone acetate: Influence of formulation in higher viscosity gel. Arch Ophthalmol, 99:2028-2029
34. Law SL, Huang KJ, Chiang CH. (2000). Acyclovir-containing liposomes for potential ocular delivery corneal. penetration and absorption. J Control Release, 63:135-140
35. Majumdar S, Hippalgaonkar K, Repka M. (2008). Effect of chitosan, benzalkonium chloride and ethylenediaminetetraacetic acid on permeation of acyclovir across isolated rabbit cornea. Int J Pharm, 348:175-178
36. Felt O, Carrel A, Baehni P, Buri P, Gurny R. (2000). Chitosan as tear substituent: A wetting agent endowed with antimicrobial efficacy. J Ocul Pharmacol Ther, 16:261-270
37. Charoo NA, Kohli K, Ali A, Anwer A. (2003). Ophthalmic delivery of ciprofloxacin hydrochloride from different polymer formulations: In vitro and in vivo studies. Drug Dev Ind Pharm, 29:215-221