Differential effects of halothane and sevoflurane on hypoxia-induced intracellular calcium transients of neonatal rat carotid body type i cells

British Journal of Anaesthesia

Volumn 103, Issue 5, 2009, Pages 701-710

  Pandit, J J ^a   Buckler, K J ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b Physiology and Genetics ^*  (United Kingdom)

Author keywords

Chemoreflexes; Ions, ion channels; Receptors, chemoreceptors, carotid body; Ventilation, hypoxic response

Indexed keywords

CALCIUM; HALOTHANE; INDO 1; POTASSIUM; SEVOFLURANE; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CAROTID BODY; CELL; CELL HYPOXIA; CELL MEMBRANE DEPOLARIZATION; CELL TYPE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; GLOMUS CELL; INTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; LUNG VENTILATION; MINIMUM LUNG ALVEOLUS CONCENTRATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATION DEPRESSION;

EID: 74949124134     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aep223     Document Type: Article

References (58)

1. Pandit JJ. The variable effect of low-dose volatile anaesthetics on the acute ventilatory response to hypoxia in humans: a quantitative review. Anaesthesia 2002; 57: 632-643
2. Knill RL, Gelb AW. Ventilatory responses to hypoxia and hypercapnia during halothane sedation and anesthesia in man. Anesthesiology 1978; 49: 244-251
3. Knill RL, Manninen PH, Clement JL. Ventilation and chemoreflexes during enflurane sedation and anaesthesia in man. Can Anaesth Soc J 1979; 26: 353-360
4. Knill RL, Kieraszewicz HT, Dodgson BG, Clement JL. Chemical regulation of ventilation during isoflurane sedation and anaesthesia in humans. Can Anaesth Soc J 1983; 30: 607-614
5. Dahan A, Van Den Elsen MJLJ, Berkenbosch A, et al.. Effects of subanesthetic halothane on the ventilatory responses to hypercapnia and hypoxia in healthy volunteers. Anesthesiology 1994; 80: 727-738 (Pubitemid 24128935)
6. Pandit JJ, Moreau B, Donoghue S, Robbins PA. Effect of pain and audiovisual stimulation on the depression of acute hypoxic ventilatory response by low dose halothane in humans. Anesthesiology 2004; 101: 1409-1416
7. Sarton E, Dahan A, Teppema L, et al.. Acute pain and central nervous system arousal do not restore impaired hypoxic ventilatory response during sevoflurane sedation. Anesthesiology 1996; 85: 295-303
8. Pandit JJ, Manning-Fox J, Dorrington KL, Robbins PA. Effects of subanaesthetic sevoflurane on ventilation. 2: Response to acute and sustained hypoxia in humans. Br J Anaesth 1999; 83: 210-216 (Pubitemid 29361128)
9. Hirshman CA, McCullough RE, Cohen PJ, Weil JV. Depression of hypoxic ventilatory response by halothane, enflurane and isoflurane in dogs. Br J Anaesth 1977; 49: 957-963
10. Gaudy J-H, Sicard J-F, Maneglia R, Quignon M. Effects of halothane on arterial blood gas equilibrium in the intact rat and chemodenervated rat. Can J Anaesth 1993; 40: 883-890
11. Davies RO, Edwards MW, Lahiri S. Halothane depresses the response of carotid body chemoreceptors to hypoxia and hypercapnia in the cat. Anesthesiology 1982; 57: 153-159
12. Ponte J, Sadler CL. Effect of halothane, enflurane and isoflurane on carotid body chemoreceptor activity in the rabbit and the cat. Br J Anaesth 1989; 62: 33-40 (Pubitemid 19212307)
13. Groeben H, Meier S, Tankersley CG, Mitzner W, Brown RH. Influence of volatile anaesthetics on hypercapnoeic ventilatory responses in mice with blunted respiratory drive. Br J Anaesth 2004; 92: 697-703
14. Pandit JJ. Volatile anesthetics and the hypoxic ventilatory response: effects, clinical implications, and future research. Semin Anesth Perioper Med Pain 2007; 26: 49-57
15. Buckler KJ, Williams BA, Honore E. An oxygen-, acid- and anaesthetic-sensitive TASK-like background potassium channel in rat arterial chemoreceptor cells. J Physiol 2000; 525: 135-142
16. Buckler KJ. A novel oxygen-sensitive potassium current in rat carotid body type I cells. J Physiol 1997; 498: 649-662
17. Buckler KJ, Vaughan-Jones RD. Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type I cells. J Physiol 1994; 476: 423-428
18. López-Barneo J, Pardal R, Ortega-Sáenz P. Cellular mechanisms of oxygen sensing. Annu Rev Physiol 2001; 63: 259-287
19. Weir KE, López-Barneo J, Buckler KJ, Archer SL. Acute oxygensensing mechanisms. N Engl J Med 2007; 353: 2042-2055
20. Prabhakar NR. O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters? Exp Physiol 2006; 91: 17-23
21. Dahan A, Sarton E, Van Den Elsen M, Van Kleef J, Teppema L, Berkenbosch A. Ventilatory response to hypoxia in humans: influences of subanesthetic desflurane. Anesthesiology 1996; 85: 60-68
22. Sarton E, Van Der Wal M, Nieuwenhuijs D, Teppema L, Robotham JL, Dahan A. Sevoflurane-induced reduction of hypoxic drive is sex-independent. Anesthesiology 1999; 90: 1288-1293
23. Buckler KJ. Background leak K+-currents and oxygen sensing in carotid body type I cells. Respir Physiol 1999; 115: 179-187
24. Buckler KJ, Vaughan-Jones RD. Effects of acidic stimuli on intracellular calcium in type I cells of the neonatal rat carotid body. Pflügers Arch 1993; 425: 22-27
25. Acker H, Lübbers DW, Purves MJ. Local oxygen tension field in the glomus caroticum of the cat and its change at changing arterial PO2. Pflügers Arch 1971; 329: 136-155
26. Acker H. PO2 chemoreception in arterial chemoreceptors. Annu Rev Physiol 1989; 51: 835-844
27. Lahiri S, Rumsey WL, Wilson DF, Iturriaga R. Contribution of in vivo microvascular PO2 in the cat carotid body chemotransduction. J Appl Physiol 1993; 75: 1035-1043 (Pubitemid 23289588)
28. Millman MS, Young M. Kinetics of dissolution of gaseous halothane in Krebs-Ringer's solution. Can J Anaesth 1992; 39: 980-986
29. Saidman LJ, Eger EI, Munson ES, Babad AA, Muallem M. Minimum alveolar concentrations of methoxyflurane, halothane, ether and cyclopropane in man: correlation with theories of anesthesia. Anesthesiology 1967; 28: 994-1002
30. Nickalls RWD, Mapleson WW. Age-related iso-MAC charts for isoflurane, sevoflurane and desflurane in man. Br J Anaesth 2003; 91: 170-174
31. Leon A, Mayzler O, Benifla M, et al.. Determining minimum alveolar concentration of halothane in rats: the effect of increment change in halothane concentration and number of crossovers. Anesth Analg 2004; 99: 1822-1828
32. Kashimoto S, Furuya A, Nanaka A, Oguchi T, Kashimuzu M, Kumuzaura T. The minimum alveolar concentration of sevoflurane in rats. Eur J Anaesthesiol 1997; 14: 359-361
33. Dasso LT, Buckler KJ, Vaughan-Jones RD. Interactions between hypoxia and hypercapnic acidosis on calcium signalling in carotid body type I cells. Am J Physiol Lung Cell Mol Physiol 2000; 279: L36-42
34. Suzuki T, Uchida I, Mashimo T. Sorptive loss of volatile and gaseous anesthetics from in vitro drug application systems. Anesth Analg 2005; 100: 427-430
35. Akata T, Nakishima M, Izumi K. Comparison of volatile anesthetic actions on intracellular calcium stores of vascular smooth muscle. Anesthesiology 2001; 94: 840-850
36. Katsuoka M, Ohnishi ST. Inhalation anaesthetics decrease calcium content of cardiac sarcoplasmic reticulum. Br J Anaesth 1989; 62: 669-673
37. Sato M. Different effects of removing extracellular Ca2+ on cytosolic Ca2+ response to anoxia of sensory neurons and carotid chemoreceptor cells from newborn rabbits. Jpn J Physiol 1995; 45: 279-289
38. Shirahata M, Fitzgerald RS. Dependency of hypoxic chemotransduction in cat carotid body on voltage-gated calcium channels. J Appl Physiol 1991; 71: 1062-1069
39. Wyatt CN, Peers C. Ca2+-activated K+ channels in isolated type I cells of the neonatal rat carotid body. J Physiol 1995; 483: 559-565
40. Wyatt CN, Buckler KJ. The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells. J Physiol 2004; 556: 175-191
41. Sanchez D, López-López JR, Pérez-García MT, et al.. Molecular identification of Kva, subunits that contribute to the oxygensensitive K+ current of chemoreceptor cells of the rabbit carotid body. J Physiol 2002; 542: 369-382
42. Biscoe TJ, Duchen MR. Cellular basis of transduction in carotid chemoreceptors. Am J Physiol Lung Cell Mol Physiol 1990; 258: L271-8
43. Weil JV. Variation in human ventilatory control-genetic influence on the hypoxic ventilatory response. Respir Physiol Neurobiol 2003; 135: 239-246
44. Bascom DA, Pandit JJ, Clement ID, Robbins PA. Effects of different levels of end-tidal PO2 on ventilation during isocapnia in humans. Respir Physiol 1992; 88: 299-311
45. Sjögren D, Lindahl SGE, Gottlieb C, Sollevi A. Ventilatory responses to acute and sustained hypoxia during sevoflurane anesthesia in women. Anesth Analg 1999; 89: 209-214
46. Patel AJ, Honoré E, Lesage F, Fink M, Romey G, Lazdunski M. Inhalational anesthetics activate two-pore-domain background K+ channels. Nat Neurosci 1999; 2: 422-426
47. Bayliss DA, Sirois JE, Talley EM. The TASK family: two-pore domain background K+ channels. Mol Interv 2003; 3: 205-219
48. Putzke C, Hanley PJ, Schlichthö rl G, et al.. Differential effects of volatile and intravenous anesthetics on the activity of human TASK-1. Am J Physiol Cell Physiol 2007; 293: C1319-26
49. Cotten JF, Miller KW. Volatile anesthetic regulation of TASK tandem pore potassium channels. Anesthesiology 2006; 105: A170
50. Pongs O, Leicher T, Berger M, et al.. Functional and molecular aspects of voltage-gated K+ channel beta subunits. Ann N Y Acad Sci 1999; 868: 344-355
51. Kaczorowski GJ, Knaus HG, Leonard RJ, McManus OB, Garcia ML. High-conductance calcium-activated potassium channels; structure, pharmacology, and function. J Bioenerg Biomembr 1996; 28: 255-267
52. Overholt JL, Prabakhar N. Ca2+ current in rabbit carotid body glomus cells is conducted by multiple types of high-voltageactivated Ca2+ channels. J Neurophysiol 1997; 78: 2467-2474
53. Dolphin AC. A short history of voltage-gated calcium channels. Br J Pharmacol 2006; 147: S56-62
54. Vicario I, Obeso A, Rocher A, López-Lopez JR, González C. Intracellular Ca2+ stores in chemoreceptor cells of the rabbit carotid body: significance for chemoreception. Am J Physiol Cell Physiol 2000; 279: C51-61
55. Wanaverbecq N, Marsh SJ, Al-Qatari M, Brown DA. The plasma membrane calcium-ATPase as a major mechanism for intracellular calcium regulation in neurones from the rat superior cervical ganglion. J Physiol 2003; 550: 83-101
56. Lingamaneni R, Hemmings HC. Differential interaction of anaesthetics and antiepileptic drugs with neuronal Na+ channels, Ca2+ channels, and GABAA receptors. Br J Anaesth 2003; 90: 199-211
57. Park WK, Kim MH, Ahn DS, et al.. Myocardial depressant effects of desflurane: mechanical and electrophysiologic actions in vitro. Anesthesiology 2007; 106: 956-966
58. Jonsson MM, Lindahl S, Eriksson LI. Effect of propofol on carotid body chemosensitivity and cholinergic chemotransduction. Anesthesiology 2005; 102: 110-116