Variation in human ventilatory control - Genetic influence on the hypoxic ventilatory response

Respiratory Physiology and Neurobiology

Volumn 135, Issue 2-3, 2003, Pages 239-246

  Weil, J V ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Carotid body, hypoxia; Chemosensitivity, peripheral, genetic influence; Control of breathing, ventilatory response to hypoxia, hypercapnia; Hypercapnia, ventilatory response; Hypoxia, ventilatory response; Mammals, cat, humans, rat

Indexed keywords

FAMILY HISTORY; GENETIC LINKAGE; HUMAN; HYPOXIA; MONOZYGOTIC TWINS; NONHUMAN; PRIORITY JOURNAL; RESPIRATION CONTROL; REVIEW;

EID: 0038384578     PISSN: 15699048     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1569-9048(03)00048-X     Document Type: Review

References (41)

1. Akiyama Y., Nishimura M., Suzuki A., Yamamoto M., Kawakami Y. Peripheral chemosensitivity assessed by the modified transient O2 test in female twins. Chest. 100:1991;102-105.
2. Arkinstall W.W., Nirmel K., Klissouras V., Milic-Emili J. Genetic differences in the ventilatory response to inhaled CO2. J. Appl. Physiol. 36:1974;6-11.
3. Beral V., Read D.J. Insensitivity of respiratory centre to carbon dioxide in the Enga people of New Guinea. Lancet. 2:1971;1290-1294.
4. Bjurstrom R.L., Schoene R.B. Control of ventilation in elite synchronized swimmers. J. Appl. Physiol. 63:1987;1019-1024.
5. Black C.P., Tenney S.M. Oxygen transport during progressive hypoxia in high-altitude and sea-level waterfowl. Respir. Physiol. 39:1980;217-239.
6. Byrne-Quinn E., Weil J.V., Sodal I.E., Filley G.F., Grover R.F. Ventilatory control in the athlete. J. Appl. Physiol. 30:1971;91-98.
7. Byrne-Quinn E., Sodal I.E., Weil J.V. Hypoxic and hypercapnic ventilatory drives in children native to high altitude. J. Appl. Physiol. 32:1972;44-46.
8. Collins D.D., Scoggin C.H., Zwillich C.W., Weil J.V. Hereditary aspects of decreased hypoxic response. J. Clin. Invest. 62:1978;105-110.
9. Fleetham J.A., Arnup M.E., Anthonisen N.R. Familial aspects of ventilatory control in patients with chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 129:1984;3-7.
10. Hirshman C.A., McCullough R.E., Weil J.V. Normal values for hypoxic and hypercapnic ventilaroty drives in man. J. Appl. Physiol. 38:1975;1095-1098.
11. Hudgel D.W., Weil J.V. Asthma associated with decreased hypoxic ventilatory drive. A family. Ann. Intern. Med. 80:1974;623-625.
12. Kawakami Y., Irie T., Kishi F., Asanuma Y., Shida A., Yoshikawa T., Kamishima K., Hasegawa H., Murao M. Familial aggregation of abnormal ventilatory control and pulmonary function in chronic obstructive pulmonary disease. Eur. J. Respir. Dis. 62:1981;56-64.
13. Kawakami Y., Irie T., Shida A., Yoshikawa T. Familial factors affecting arterial blood gas values and respiratory chemosensitivity in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 125:1982;420-425.
14. Kawakami Y., Yoshikawa T., Shida A., Asanuma Y., Murao M. Control of breathing in young twins. J. Appl. Physiol.: Respir. Environ. Exerc. Physiol. 52:1982;537-542.
15. Kawakami Y., Yamamoto H., Yoshikawa T., Shida A. Chemical and behavioral control of breathing in adult twins. Am. Rev. Respir. Dis. 129:1984;703-707.
16. Kobayashi S., Nishimura M., Yamamoto M., Akiyama Y., Kishi F., Kawakami Y. Dyspnea sensation and chemical control of breathing in adult twins. Am. Rev. Respir. Dis. 147:1993;1192-1198.
17. Lane D.J., Howell J.B. Relationship between sensitivity to carbon dioxide and clinical features in patients with chronic airways obstruction. Thorax. 25:1970;150-159.
18. Leitch A.G. Chemical control of breathing in identical twin athletes. Ann. Hum. Biol. 3:1976;447-454.
19. Levine B.D., Friedman D.B., Engfred K., Hanel B., Kjaer M., Clifford P.S., Secher N.H. The effect of normoxic or hypobaric hypoxic endurance training on the hypoxic ventilatory response. Med. Sci. Sports Exerc. 24:1992;769-775.
20. Markov G., Orler R., Boutellier U. Respiratory training, hypoxic ventilatory response and acute mountain sickness. Respir. Physiol. 105:1996;179-186.
21. Masuyama S., Kimura H., Sugita T., Kuriyama T., Tatsumi K., Kunitomo F., Okita S., Tojima H., Yuguchi Y., Watanabe S., et al. Control of ventilation in extreme-altitude climbers. J. Appl. Physiol. 61:1986;500-506.
22. Matsuzawa Y., Fujimoto K., Kobayashi T., Namushi N.R., Harada K., Kohno H., Fukushima M., Kusama S. Blunted hypoxic ventilatory drive in subjects susceptible to high-altitude pulmonary edema. J. Appl. Physiol. 66:1989;1152-1157.
23. Matthews A.W., Howell J.B. Assessment of responsiveness to carbon dioxide in patients with chronic airways obstruction by rate of isometric inspiratory pressure development. Clin. Sci. Mol. Med. 50:1976;199-205.
24. Moore G.C., Zwillich C.W., Battaglia J.D., Cotton E.K., Weil J.V. Respiratory failure associated with familial depression of ventilatory response to hypoxia and hypercapnia. N. Engl. J. Med. 295:1976;861-865.
25. Moore L.G., Harrison G.L., McCullough R.E., McCullough R.G., Micco A.J., Tucker A., Weil J.V., Reeves J.T. Low acute hypoxic ventilatory response and hypoxic depression in acute altitude sickness. J. Appl. Physiol. 60:1986;1407-1412.
26. Mountain R., Zwillich C., Weil J. Hypoventilation in obstructive lung disease. The role of familial factors. N. Engl. J. Med. 298:1978;521-525.
27. Ohyabu Y., Usami A., Ohyabu I., Ishida Y., Miyagawa C., Arai T., Honda Y. Ventilatory and heart rate chemosensitivity in track-and-field athletes. Eur. J. Appl. Physiol. Occup. Physiol. 59:1990;460-464.
28. Redline S., Leitner J., Arnold J., Tishler P.V., Altose M.D. Ventilatory-control abnormalities in familial sleep apnea. Am. J. Respir. Crit. Care Med. 156:1997;155-160.
29. Robin E.D., O'Neill R.P. The fighter versus the non-fighter. Control of ventilation in chronic obstructive pulmonary disease. Arch. Environ. Hlth. 7:1963;125.
30. Scadding J.G. Meaning of diagnostic terms in bronchopulmonary disease. Br. Med. J. 2:1963;1435.
31. Schaeffer K.E. Respiratory pattern and respiratory response to CO2. J. Appl. Physiol. 13:1958;1-14.
32. Schoene R.B. Control of ventilation in climbers to extreme altitude. J. Appl. Physiol. 53:1982;886-890.
33. Schoene R.B., Robertson H.T., Pierson D.J., Peterson A.P. Respiratory drives and exercise in menstrual cycles of athletic and nonathletic women. J. Appl. Physiol. 50:1981;1300-1305.
34. Scoggin C.H., Doekel R.D., Kryger M.H., Zwillich C.W., Weil J.V. Familial aspects of decreased hypoxic drive in endurance athletes. J. Appl. Physiol. 44:1978;464-468.
35. Severinghaus J.W., Bainton C.R., Carcelen A. Respiratory insensitivity to hypoxia in chronically hypoxic man. Respir. Physiol. 1:1966;308-334.
36. Strohl, K., 2003. Periodic breathing and genetics. Respir. Physiol. Neurobiol.
37. Tankersley, C.G., 2003. Genetic aspects of breathing: on interactions between hypercapnia and hypoxia. Respir. Physiol. Neurobiol.
38. Vizek M., Pickett C.K., Weil J.V. Interindividual variation in hypoxic ventilatory response: potential role of carotid body. J. Appl. Physiol. 63:1987;1884-1889.
39. Weil J.V., Zwillich C.W. Assessment of ventilatory response to hypoxia: methods and interpretation. Chest. 70:1976;124-128.
40. Weil J.V., Byrne-Quinn E., Sodal I.E., Filley G.F., Grover R.F. Acquired attenuation of chemoreceptor function in chronically hypoxic man at high altitude. J. Clin. Invest. 50:1971;186-195.
41. Weil J.V., Stevens T., Pickett C.K., Tatsumi K., Dickinson M.G., Jacoby C.R., Rodman D.M. Strain-associated differences in hypoxic chemosensitivity of the carotid body in rats. Am. J. Physiol. 274:1998;L767-L774.