Topical Boswellic acids for treatment of photoaged skin

Dermatologic Therapy

Volumn 23, Issue SUPPL. 1, 2010, Pages

  Calzavara Pinton, Piergiacomo ^a   Zane, Cristina ^a   Facchinetti, Elena ^a   Capezzera, Rossana ^a   Pedretti, Alessandra ^a  

^a Department of Dermatology ^*  (Italy)

Author keywords

20 MHz B mode echography; Boswellia serrata; Boswellic acids; Skin photo and chronoaging

Indexed keywords

BOSWELLIC ACID;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ECHOGRAPHY; ELASTICITY; FACE; FEMALE; HUMAN; PHOTOAGING; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEBUM SECRETION; TACTILE DISCRIMINATION; UNSPECIFIED SIDE EFFECT;

ADMINISTRATION, CUTANEOUS; ADULT; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FEMALE; HUMANS; IMMUNOLOGIC FACTORS; MIDDLE AGED; PLANT EXTRACTS; SKIN AGING; TRITERPENES;

EID: 74949123103     PISSN: 13960296     EISSN: 15298019     Source Type: Journal    
DOI: 10.1111/j.1529-8019.2009.01284.x     Document Type: Article

References (16)

1. Poeckel D, Wetz O. Boswellic acid: biological action and molecular targets. Curr Med Chem 2006 : 13 : 3359 3369.
2. Moussaieff A, Shohami E, Kashman Y, et al. Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activation. Mol Pharmacol 2007 : 72 : 1657 1664.
3. Safayhi H, Sailer ERl. Anti-inflammatory actions of pentacyclic triterpenes. Planta Med 1997 : 63 : 487 493.
4. Sashwati R, Savita K, Krishnaraju AV. Regulation of vascular responses to inflammation: inducible matrix metalloproteinase-3 expression in human microvascular endothelial cells is sensitive to anti-inflammatory Boswellia. Antioxid Redox Signal 2006 : 8 : 653 660.
5. Dover JS, Bhatia AC, Stewart B, Arndt KA. Topical 5-aminolevulinic acid combined with intense pulsed light in the treatment of photoaging. Arch Dermatol 2005 : 141 : 1247 1252.
6. Safayhi H, Sailer ER, Ammon HP. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid. Mol Pharmacol 1995 : 47 : 1212 1216.
7. Sailer ER, Schweizer S, Boden SE, Ammon HP, Safayhi H. Characterization of an acetyl-11-keto-beta-boswellic acid and arachidonate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling. Eur J Biochem 1998 : 256 : 364 368.
8. Schweizer S, Eichele K, Ammon HP, Safayhi H. 3-Acetoxy group of genuine AKBA (acetyl-11-keto-beta-boswellic acid) is alpha-configurated. Planta Med 2000 : 66 : 781 782.
9. Bannoa N, Akihisa T, Yasukawa K, Tokuda H, Tabata K, Nakamurab YL. Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri. J Ethnopharmacol 2006 : 107 : 249 253.
10. Safayhi H, Rall B, Sailer ER, Ammon HP. Inhibition by Boswellic acids of human leukocyte elastase. J Pharnacol exp Ther 1997 : 281 : 460 463.
11. Xia L, Chen D, Han R, Fang Q, Waxman S, Jing Y. Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. Mol Cancer Ther. 2005 : 4 : 381 388.
12. Liu JJ, Huang B, Hooi SC. Acetyl-keto-beta-boswellic acid inhibits cellular proliferation through a p21-dependent pathway in colon cancer cells. Br. J. Pharmacol 2006 : 148 : 1099 1107.
13. Glaser T, Winter S, Groscurth P, et al. Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. Br J Cancer 1999 : 80 : 756 765.
14. Park YS, Lee JH, Harwalkar JA, Bondar J, Safayhi H, Golubic M. Acetyl-11-keto-beta-boswellic acid (AKBA) is cytotoxic for meningioma cells and inhibits phosphorylation of the extracellular-signal regulated kinase 1 and 2. Adv Exp Med Biol 2002 : 507 : 387 393.
15. Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002 : 3 : 2087 2093.
16. Jing Y, Nakajo S, Xia L, et al. Boswellic acid acetate induces differentiation and apoptosis in leukemia cell lines. Leuk Res 1999 : 23 : 43 50.