A single exposure to particulate or gaseous air pollution increases the risk of aconitine-induced cardiac arrhythmia in hypertensive rats

Toxicological Sciences

Volumn 112, Issue 2, 2009, Pages 532-542

  Hazari, Mehdi S ^a   Haykal Coates, Najwa ^a   Winsett, Darrell W ^a   Costa, Daniel L ^a   Farraj, Aimen K ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Aconitine; Air pollution; Cardiac arrhythmia; Inhalation

Indexed keywords

ACONITINE; ACROLEIN;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; ASH; BLOOD PRESSURE; BODY WEIGHT; CONTROLLED STUDY; ELECTROCARDIOGRAM; ENVIRONMENTAL EXPOSURE; HEART ARRHYTHMIA; HEART RATE; HEART RATE VARIABILITY; HYPERTENSION; MALE; NONHUMAN; PARTICLE SIZE; PARTICULATE MATTER; PR INTERVAL; QRS COMPLEX; QT INTERVAL; RAT; RISK FACTOR; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT; ANIMAL; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; DRUG EFFECT; ELECTROCARDIOGRAPHY;

RATTUS;

ACONITINE; AIR POLLUTION; ANIMALS; ARRHYTHMIAS, CARDIAC; BLOOD PRESSURE; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; HEART RATE; PARTICLE SIZE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RISK FACTORS;

EID: 74949118307     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp214     Document Type: Article

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