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Volumn 3, Issue 6, 2009, Pages 429-439

EXCEED: Exforge®-intensive control of hypertension to evaluate efficacy in diastolic dysfunction: Study rationale, design, and participant characteristics

Author keywords

Amlodipine; Angiotensin receptor blockers; Calcium channel blockers; Diastolic dysfunction; EXCEED; Hypertension; Valsartan

Indexed keywords

AMLODIPINE; AMLODIPINE VALSARTAN; AMLODIPINE-VALSARTAN; ANTIHYPERTENSIVE AGENT; TETRAZOLE DERIVATIVE; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMLODIPINE PLUS VALSARTAN; ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROCHLOROTHIAZIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

EID: 74949084083     PISSN: 17539447     EISSN: None     Source Type: Journal    
DOI: 10.1177/1753944709341301     Document Type: Article
Times cited : (9)

References (36)
  • 1
    • 0347423198 scopus 로고    scopus 로고
    • The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Chobanian, A.V., Bakris, G.L., Black, H.R., Cushman, W.C., Green, L.A., Izzo, J.L. et al. (2003) The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42: 1206-1252.
    • (2003) Hypertension , vol.42 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo, J.L.6
  • 2
    • 34247263709 scopus 로고    scopus 로고
    • Effects of valsartan or amlodipine alone or in combination on plasma catecholamine levels at rest and during standing in hypertensive patients
    • de Champlain, J., Karas, M., Assouline, L., Le Blanc, A.R., Dubé, B. and Larochelle, P. ( 2007) Effects of valsartan or amlodipine alone or in combination on plasma catecholamine levels at rest and during standing in hypertensive patients. J Clin Hypertens 9: 168-178.
    • (2007) J Clin Hypertens , vol.9 , pp. 168-178
    • de Champlain, J.1    Karas, M.2    Assouline, L.3    Le Blanc, A.R.4    Dubé, B.5    Larochelle, P.6
  • 3
    • 0022588019 scopus 로고
    • Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings
    • Devereux, R.B., Alonso, D.R., Lutas, E.M., Gottlieb, G.J., Campo, E., Sachs, I. et al. (1986) Echocardiographic assessment of left ventricular hypertrophy: comparison to necropsy findings. Am J Cardiol 57: 450-458.
    • (1986) Am J Cardiol , vol.57 , pp. 450-458
    • Devereux, R.B.1    Alonso, D.R.2    Lutas, E.M.3    Gottlieb, G.J.4    Campo, E.5    Sachs, I.6
  • 4
    • 0037188574 scopus 로고    scopus 로고
    • Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients
    • Diez, J., Querejeta, R., Lopez, B., González, A., Larman, M., José, L. et al. (2002) Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients. Circulation 105: 2512-2517.
    • (2002) Circulation , vol.105 , pp. 2512-2517
    • Diez, J.1    Querejeta, R.2    Lopez, B.3    González, A.4    Larman, M.5    José, L.6
  • 5
    • 0141504294 scopus 로고    scopus 로고
    • The left atrium: a marker of chronic diastolic dysfunction and cardiovascular disease risk
    • Douglas, P.S. ( 2003) The left atrium: a marker of chronic diastolic dysfunction and cardiovascular disease risk. J Am Coll Cardiol 42: 1206-1207.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1206-1207
    • Douglas, P.S.1
  • 6
    • 1542358948 scopus 로고    scopus 로고
    • Left ventricular diastolic dysfunction and diastolic heart failure
    • Gaasch, W.H. and Zile, M.R. ( 2004) Left ventricular diastolic dysfunction and diastolic heart failure. Annu Rev Med 55: 373-394.
    • (2004) Annu Rev Med , vol.55 , pp. 373-394
    • Gaasch, W.H.1    Zile, M.R.2
  • 7
    • 27544500053 scopus 로고    scopus 로고
    • What is the normal range for N-terminal pro-brain natriuretic peptide? How well does this normal range screen for cardiovascular disease
    • Gavin, I.W., Avijit, L., Sophie, C.B., Collinson, P. and Senior, R. ( 2005) What is the normal range for N-terminal pro-brain natriuretic peptide? How well does this normal range screen for cardiovascular disease ? Eur Heart J 26: 2269-2276.
    • (2005) Eur Heart J , vol.26 , pp. 2269-2276
    • Gavin, I.W.1    Avijit, L.2    Sophie, C.B.3    Collinson, P.4    Senior, R.5
  • 8
    • 0026911107 scopus 로고
    • Prospective Randomized Open Blinded End-point (PROBE) Study: A novel design for intervention trials
    • Hansson, L., Hender, T. and Dahlof, B. ( 1992) Prospective Randomized Open Blinded End-point (PROBE) Study: A novel design for intervention trials. Blood Press 1: 113-119.
    • (1992) Blood Press , vol.1 , pp. 113-119
    • Hansson, L.1    Hender, T.2    Dahlof, B.3
  • 9
    • 0036399538 scopus 로고    scopus 로고
    • Tissue Doppler analysis of age-dependency in diastolic ventricular behavior and filling: a cross-sectional study of healthy hearts (the Umea General Population Heart Study)
    • Henein, M., Lindqvist, P., Francis, D., Waldenström, A. and Kazzam, E. ( 2002) Tissue Doppler analysis of age-dependency in diastolic ventricular behavior and filling: a cross-sectional study of healthy hearts (the Umea General Population Heart Study). Eur Heart J 23: 162-171.
    • (2002) Eur Heart J , vol.23 , pp. 162-171
    • Henein, M.1    Lindqvist, P.2    Francis, D.3    Waldenström, A.4    Kazzam, E.5
  • 10
    • 0024552554 scopus 로고
    • Pulsatile diameter and elastic modulus of the aortic arch in essential hypertension: a non-invasive study
    • Isnard, R.N., Pannier, B.M., Laurent, S., London, G.M., Diebold, B. and Safar, M.E. ( 1989) Pulsatile diameter and elastic modulus of the aortic arch in essential hypertension: a non-invasive study. J Am Coll Cardiol 13: 399-405.
    • (1989) J Am Coll Cardiol , vol.13 , pp. 399-405
    • Isnard, R.N.1    Pannier, B.M.2    Laurent, S.3    London, G.M.4    Diebold, B.5    Safar, M.E.6
  • 11
    • 33744531103 scopus 로고    scopus 로고
    • Your drug, my drug, or our drugs How aggressive should we be with antihypertensive therapy?
    • Izzo, J.L. ( 2005) Your drug, my drug, or our drugs How aggressive should we be with antihypertensive therapy? J Clin Hypertens 7: 5-7.
    • (2005) J Clin Hypertens , vol.7 , pp. 5-7
    • Izzo, J.L.1
  • 12
    • 10444257232 scopus 로고    scopus 로고
    • Influence of alterations in loading on mitral annular velocity by tissue Doppler echocardiography and its associated ability to predict filling pressures
    • Jacque, D.C., Pinsky, M., Severyn, D. and Gorcsan, J. ( 2004) Influence of alterations in loading on mitral annular velocity by tissue Doppler echocardiography and its associated ability to predict filling pressures. Chest 126: 1910-1918.
    • (2004) Chest , vol.126 , pp. 1910-1918
    • Jacque, D.C.1    Pinsky, M.2    Severyn, D.3    Gorcsan, J.4
  • 13
    • 0038642326 scopus 로고    scopus 로고
    • A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension
    • Klingbeil, A.U., Schneider, M., Martus, P., Messerli, F.H. and Schmieder, R.E. ( 2003) A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension. Am J Med 115: 41-46.
    • (2003) Am J Med , vol.115 , pp. 41-46
    • Klingbeil, A.U.1    Schneider, M.2    Martus, P.3    Messerli, F.H.4    Schmieder, R.E.5
  • 14
    • 0030004173 scopus 로고    scopus 로고
    • Change in aortic end-systolic pressure by alterations in loading sequence and its relation to left ventricular isovolumic relaxation
    • Kohno, F., Kumada, T., Kambayashi, M., Hayashida, W., Ishikawa, N. and Sasayama, S. ( 1996) Change in aortic end-systolic pressure by alterations in loading sequence and its relation to left ventricular isovolumic relaxation. Circulation 93: 2080-2087.
    • (1996) Circulation , vol.93 , pp. 2080-2087
    • Kohno, F.1    Kumada, T.2    Kambayashi, M.3    Hayashida, W.4    Ishikawa, N.5    Sasayama, S.6
  • 15
    • 29244432482 scopus 로고    scopus 로고
    • Recommendations for Chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology
    • Lang, R.M., Bierig, M., Devereux, R.B., Flachskampf, F.A., Foster, E., Patricia, A. et al. (2005) Recommendations for Chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, Developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 18: 1440-1463.
    • (2005) J Am Soc Echocardiogr , vol.18 , pp. 1440-1463
    • Lang, R.M.1    Bierig, M.2    Devereux, R.B.3    Flachskampf, F.A.4    Foster, E.5    Patricia, A.6
  • 16
    • 0037079309 scopus 로고    scopus 로고
    • Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Prospective Studies Collaboration
    • Lewington, S., Clarke, R., Qizilbash, N., Peto, R. and Collins, R. ( 2002) Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Prospective Studies Collaboration. Lancet 360: 1903-1913.
    • (2002) Lancet , vol.360 , pp. 1903-1913
    • Lewington, S.1    Clarke, R.2    Qizilbash, N.3    Peto, R.4    Collins, R.5
  • 17
    • 33745427625 scopus 로고    scopus 로고
    • Angiotensin II stimulates T-type calcium channel current via activation of a G protein
    • Lu, H.K., Fern, R.J., Luthin, D., Linden, J., Liu, L.P., Cohen, C.J. et al. (1996) Angiotensin II stimulates T-type calcium channel current via activation of a G protein. Am J Physiol 271: C1340-C1349.
    • (1996) Am J Physiol , vol.271 , pp. C1340-C1349
    • Lu, H.K.1    Fern, R.J.2    Luthin, D.3    Linden, J.4    Liu, L.P.5    Cohen, C.J.6
  • 18
    • 0025853105 scopus 로고
    • Reversal of changes in left ventricular diastolic filling associated with normal aging using diltiazem
    • Manning, W.J., Shannon, R.P., Santinga, J.A., Parker, J.A., Gervino, E.V., Come, P.C. et al. (1991) Reversal of changes in left ventricular diastolic filling associated with normal aging using diltiazem. Am J Cardiol 67: 894-896.
    • (1991) Am J Cardiol , vol.67 , pp. 894-896
    • Manning, W.J.1    Shannon, R.P.2    Santinga, J.A.3    Parker, J.A.4    Gervino, E.V.5    Come, P.C.6
  • 19
    • 0034617175 scopus 로고    scopus 로고
    • Cardiac intracellular calcium release channels: role in heart failure
    • Marks, A.R. ( 2000) Cardiac intracellular calcium release channels: role in heart failure. Circ Res 87: 8-11.
    • (2000) Circ Res , vol.87 , pp. 8-11
    • Marks, A.R.1
  • 20
    • 0025773177 scopus 로고
    • Abnormal intracellular modulation of calcium as a major cause of cardiac contractile dysfunction
    • Morgan, J.P. ( 1991) Abnormal intracellular modulation of calcium as a major cause of cardiac contractile dysfunction. N Engl J Med 325: 625-632.
    • (1991) N Engl J Med , vol.325 , pp. 625-632
    • Morgan, J.P.1
  • 21
    • 38349101374 scopus 로고    scopus 로고
    • Attenuated radial augmentation index is associated with successful long term antihypertensive treatment
    • Ohno, Y., Kanno, Y., Mauruyama, T., Morii, T., Eguchi, T., Hirao, K. et al. (2008) Attenuated radial augmentation index is associated with successful long term antihypertensive treatment. J Human Hypertens 22: 144-146.
    • (2008) J Human Hypertens , vol.22 , pp. 144-146
    • Ohno, Y.1    Kanno, Y.2    Mauruyama, T.3    Morii, T.4    Eguchi, T.5    Hirao, K.6
  • 23
    • 34447109035 scopus 로고    scopus 로고
    • Two multicenter, 8 weeks, randomized, double blind, placebo-controlled, parallel group studies evaluating the efficacy and tolerability of Amlodipine and Valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension
    • Philip, T., Smith, T.R., Glazer, R., Wernsing, M., Yen, J., Jin, J. et al. (2007) Two multicenter, 8 weeks, randomized, double blind, placebo-controlled, parallel group studies evaluating the efficacy and tolerability of Amlodipine and Valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension. Clin Therapeut 29: 563-580.
    • (2007) Clin Therapeut , vol.29 , pp. 563-580
    • Philip, T.1    Smith, T.R.2    Glazer, R.3    Wernsing, M.4    Yen, J.5    Jin, J.6
  • 25
    • 0025129567 scopus 로고
    • Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance
    • Setaro, J.F., Zaret, B.L., Schulman, D.S., Black, H.R. and Soufer, R. ( 1990) Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ventricular systolic performance. Am J Cardiol 66: 981-986.
    • (1990) Am J Cardiol , vol.66 , pp. 981-986
    • Setaro, J.F.1    Zaret, B.L.2    Schulman, D.S.3    Black, H.R.4    Soufer, R.5
  • 27
    • 34250689098 scopus 로고    scopus 로고
    • Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic dysfunction in patients with hypertension and diastolic dysfunction: a randomized trial
    • Solomon, S.D., Janardhanan, R., Verma, A., Bourgoun, M., Daley, W.L., Purkayastha, D. et al. (2007) Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic dysfunction in patients with hypertension and diastolic dysfunction: a randomized trial. Lancet 369: 2079-2087.
    • (2007) Lancet , vol.369 , pp. 2079-2087
    • Solomon, S.D.1    Janardhanan, R.2    Verma, A.3    Bourgoun, M.4    Daley, W.L.5    Purkayastha, D.6
  • 28
    • 0344896668 scopus 로고    scopus 로고
    • Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension
    • Takami, T. and Shigematsu, M. ( 2003) Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension. Clin Experiment Hypertens 25: 525-535.
    • (2003) Clin Experiment Hypertens , vol.25 , pp. 525-535
    • Takami, T.1    Shigematsu, M.2
  • 29
    • 0141839014 scopus 로고    scopus 로고
    • Prediction of risk for first age-related cardiovascular events in an elderly population
    • Tsang, T.S., Barnes, M.E. and Gersh, B.J. ( 2003) Prediction of risk for first age-related cardiovascular events in an elderly population. J Am Coll Cardiol 42: 1199-1205.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1199-1205
    • Tsang, T.S.1    Barnes, M.E.2    Gersh, B.J.3
  • 30
    • 0029793195 scopus 로고    scopus 로고
    • The role of hypertension in the pathogenesis of heart failure. A clinical mechanistic overview
    • Vasan, R.S. and Levy, D. ( 1996) The role of hypertension in the pathogenesis of heart failure. A clinical mechanistic overview. Arch Intern Med 156: 1789-1796.
    • (1996) Arch Intern Med , vol.156 , pp. 1789-1796
    • Vasan, R.S.1    Levy, D.2
  • 31
    • 0035904776 scopus 로고    scopus 로고
    • Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: A cohort study
    • Vasan, R.S., Larson, M.G., Leip, E.P., Kannel, W.B. and Levy, D. ( 2001) Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: A cohort study. Lancet 358: 1682-1686.
    • (2001) Lancet , vol.358 , pp. 1682-1686
    • Vasan, R.S.1    Larson, M.G.2    Leip, E.P.3    Kannel, W.B.4    Levy, D.5
  • 33
    • 0032407096 scopus 로고    scopus 로고
    • Ambulatory pulse pressure: a potent predictor of total cardiovascular risk in hypertension
    • Verdecchia, P., Schillaci, G., Borgioni, C., Ciucci, A., Pede, S. and Porcella, C. ( 1998) Ambulatory pulse pressure: a potent predictor of total cardiovascular risk in hypertension. Hypertension 32: 983-988.
    • (1998) Hypertension , vol.32 , pp. 983-988
    • Verdecchia, P.1    Schillaci, G.2    Borgioni, C.3    Ciucci, A.4    Pede, S.5    Porcella, C.6
  • 34
    • 0037022929 scopus 로고    scopus 로고
    • Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study
    • Wachtell, K., Bella, J.N., Rokkedal, J., Vittorio Palmieri, V., Papademetriou, V., Dahlöf, B. et al. (2002) Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study. Circulation 105: 1071-1076.
    • (2002) Circulation , vol.105 , pp. 1071-1076
    • Wachtell, K.1    Bella, J.N.2    Rokkedal, J.3    Vittorio Palmieri, V.4    Papademetriou, V.5    Dahlöf, B.6
  • 35
    • 34547867315 scopus 로고    scopus 로고
    • World Health Report
    • World Health Organization Geneva Switzerland, Available at
    • World Health Report (2002) Reducing risks, promoting healthy life. World Health Organization : Geneva, Switzerland, Available at: http://www.who.int/whr/ 2002
    • (2002) Reducing risks, promoting healthy life
  • 36
    • 0037133660 scopus 로고    scopus 로고
    • New concepts in diastolic dysfunction and diastolic heart failure: I. Diagnosis, prognosis, and measurements of diastolic function
    • Zile, M. and Brutsaert, D. ( 2002) New concepts in diastolic dysfunction and diastolic heart failure: I. Diagnosis, prognosis, and measurements of diastolic function. Circulation 105: 1387.
    • (2002) Circulation , vol.105 , pp. 1387
    • Zile, M.1    Brutsaert, D.2


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