Defining the therapeutic window of vertebral photodynamic therapy in a murine pre-clinical model of breast cancer metastasis using the photosensitizer BPD-MA (Verteporfin)

Breast Cancer Research and Treatment

Volumn 119, Issue 2, 2010, Pages 325-333

  Akens, Margarete K ^a   Hardisty, Michael R ^a   Wilson, Brian C ^b   Schwock, Joerg ^b   Whyne, Cari M ^a   Burch, Shane ^c   Yee, Albert J M ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bone metastasis; Breast cancer; Photodynamic therapy; Spine

Indexed keywords

LUCIFERASE; VERTEPORFIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; BREAST CARCINOMA; CARCINOMA CELL; CONTROLLED STUDY; DRUG DOSE ESCALATION; DRUG DOSE REDUCTION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUMBAR SPINE; MORPHOMETRICS; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RAT; SPINE METASTASIS; THORACIC SPINE; TREATMENT OUTCOME;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GENES, REPORTER; HUMANS; LUCIFERASES; LUMBAR VERTEBRAE; MICE; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; RATS; RATS, NUDE; SPINAL NEOPLASMS; THORACIC VERTEBRAE; TIME FACTORS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 74849128016     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0356-7     Document Type: Article

References (33)

1. A Lipton 2003 Bone metastases in breast cancer Curr Treat Options Oncol 4 151 158 10.1007/s11864-003-0016-9 10.1007/s11864-003-0016-9 12594941
2. RD Ecker T Endo NM Wetjen WE Krauss 2005 Diagnosis and treatment of vertebral column metastases Mayo Clin Proc 80 1177 1186 10.4065/80.9.1177 16178498
3. M Clemons G Dranitsaris D Cole MC Gainford 2006 Too much, too little, too late to start again? Assessing the efficacy of bisphosphonates in patients with bone metastases from breast cancer Oncologist 11 227 233 10.1634/theoncologist. 11-3-227 10.1634/theoncologist.11-3-227 1:CAS:528:DC%2BD28XhtFKlsbzN 16549806
4. H Tatsui T Onomura S Morishita M Oketa T Inoue 1996 Survival rates of patients with metastatic spinal cancer after scintigraphic detection of abnormal radioactive accumulation Spine 21 2143 2148 10.1097/00007632-199609150-00017 10.1097/00007632-199609150-00017 1:STN:280:DyaK2s%2FkvVKjuw%3D%3D 8893440 (Pubitemid 26330601)
5. H Katagiri M Takahashi J Inagaki H Kobayashi H Sugiura S Yamamura H Iwata 1998 Clinical results of nonsurgical treatment for spinal metastases Int J Radiat Oncol Biol Phys 42 1127 1132 10.1016/S0360-3016(98)00288-0 1:STN:280:DyaK1M%2FosVGrtg%3D%3D 9869239 (Pubitemid 29004158)
6. EK Wai JA Finkelstein RP Tangente L Holden E Chow M Ford A Yee 2003 Quality of life in surgical treatment of metastatic spine disease Spine 28 508 512 10.1097/00007632-200303010-00018 10.1097/00007632-200303010-00018 12616166 (Pubitemid 36330842)
7. SK Powers SS Cush DL Walstad L Kwock 1991 Stereotactic intratumoral photodynamic therapy for recurrent malignant brain tumors Neurosurgery 29 688 695 10.1097/00006123-199111000-00008 10.1097/00006123-199111000-00008 1:STN:280:DyaK38%2Fnt1yrsA%3D%3D 1835765 (discussion 695-696)
8. NE Marcon 1994 Photodynamic therapy and cancer of the esophagus Semin Oncol 21 20 23 1:STN:280:DyaK2M%2FosVaiuw%3D%3D 7992103
9. S Lam 1994 Photodynamic therapy of lung cancer Semin Oncol 21 15 19 1:STN:280:DyaK2M%2FosVaiug%3D%3D 7992102
10. R Allison T Mang G Hewson W Snider D Dougherty 2001 Photodynamic therapy for chest wall progression from breast carcinoma is an underutilized treatment modality Cancer 91 1 8 10.1002/1097-0142(20010101)91:1<1::AID-CNCR1>3.0. CO;2-P 10.1002/1097-0142(20010101)91:1<1::AID-CNCR1>3.0.CO;2-P 1:STN:280:DC%2BD38%2Fgs1Smtg%3D%3D 11148553 (Pubitemid 32052607)
11. MA Biel 2007 Photodynamic therapy treatment of early oral and laryngeal cancers Photochem Photobiol 83 1063 1068 10.1111/j.1751-1097.2007.00153.x 10.1111/j.1751-1097.2007.00153.x 1:CAS:528:DC%2BD2sXhtFGhurjL 17880501 (Pubitemid 47438525)
12. E Buytaert M Dewaele P Agostinis 2007 Molecular effectors of multiple cell death pathways initiated by photodynamic therapy Biochim Biophys Acta 1776 86 107 1:CAS:528:DC%2BD2sXpvFWmsLg%3D 17693025
13. M Niedre MS Patterson BC Wilson 2002 Direct near-infrared luminescence detection of singlet oxygen generated by photodynamic therapy in cells in vitro and tissues in vivo Photochem Photobiol 75 382 391 10.1562/0031-8655(2002) 075<0382:DNILDO>2.0.CO;2 10.1562/0031-8655(2002)075<0382:DNILDO>2.0. CO;2 1:CAS:528:DC%2BD38Xjt1altb8%3D 12003128
14. S Verma GM Watt Z Mai T Hasan 2007 Strategies for enhanced photodynamic therapy effects Photochem Photobiol 83 996 1005 10.1111/j.1751-1097.2007.00166.x 10.1111/j.1751-1097.2007.00166.x 1:CAS:528:DC%2BD2sXhtFGhurvE 17880492 (Pubitemid 47438530)
15. S Burch SK Bisland A Bogaards AJ Yee CM Whyne JA Finkelstein BC Wilson 2005 Photodynamic therapy for the treatment of vertebral metastases in a rat model of human breast carcinoma J Orthop Res 23 995 1003 10.1016/j.orthres.2004. 12.014 10.1016/j.orthres.2004.12.014 1:CAS:528:DC%2BD2MXpslygtr8%3D 16140186 (Pubitemid 41245421)
16. MK Akens AJM Yee BC Wilson S Burch CL Johnson L Lilge SK Bisland 2007 Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma Photochem Photobiol 83 1034 1039 10.1111/j.1751-1097.2007.00172.x 10.1111/j.1751-1097.2007.00172.x 1:CAS:528:DC%2BD2sXhtFGhurjP 17880497 (Pubitemid 47438533)
17. AM Richter S Cerruti-Sola ED Sternberg D Dolphin JG Levy 1990 Biodistribution of tritiated benzoporphyrin derivative (3H-BPD-MA), a new potent photosensitizer, in normal and tumor-bearing mice J Photochem Photobiol B 5 231 244 10.1016/1011-1344(90)80008-L 10.1016/1011-1344(90)80008-L 1:CAS:528:DyaK3cXltFWltbs%3D 2111398
18. SG Parekh KB Trauner B Zarins TE Foster RR Anderson 1999 Photodynamic modulation of wound healing with BPD-MA and CASP Lasers Surg Med 24 375 381 10.1002/(SICI)1096-9101(1999)24:5<375::AID-LSM8>3.0.CO;2-B 10.1002/(SICI)1096-9101(1999)24:5<375::AID-LSM8>3.0.CO;2-B 1:STN:280:DyaK1MzjtlWgtA%3D%3D 10406478 (Pubitemid 29314268)
19. DM Basso MS Beattie JC Bresnahan 1995 A sensitive and reliable locomotor rating scale for open field testing in rats J Neurotrauma 12 1 21 10.1089/neu.1995.12.1 1:STN:280:DyaK2Mzgt1GhtQ%3D%3D 7783230
20. VH Fingar WR Potter BW Henderson 1987 Drug and light dose dependence of photodynamic therapy: a study of tumor cell clonogenicity and histologic changes Photochem Photobiol 45 643 650 10.1111/j.1751-1097.1987.tb07392.x 10.1111/j.1751-1097.1987.tb07392.x 1:CAS:528:DyaL2sXktVensL4%3D 2955431
21. S Burch A Bogaards J Siewerdsen D Moseley A Yee J Finkelstein R Weersink BC Wilson SK Bisland 2005 Photodynamic therapy for the treatment of metastatic lesions in bone: studies in rat and porcine models J Biomed Opt 10 34011 10.1117/1.1921887 10.1117/1.1921887 1:STN:280:DC%2BD2MrlvV2ksQ%3D%3D (Pubitemid 41236405)
22. KC Dole Q Chen FW Hetzel LR Whalen D Blanc Z Huang 2005 Effects of photodynamic therapy on peripheral nerve: in situ compound-action potentials study in a canine model Photomed Laser Surg 23 172 176 10.1089/pho.2005.23.172 10.1089/pho.2005.23.172 1:CAS:528:DC%2BD28XlsFantL4%3D 15910181 (Pubitemid 40720985)
23. ON Hausmann 2003 Post-traumatic inflammation following spinal cord injury Spinal Cord 41 369 378 10.1038/sj.sc.3101483 10.1038/sj.sc.3101483 1:STN:280:DC%2BD3s3ovValtQ%3D%3D 12815368 (Pubitemid 36819586)
24. M Bendszus G Ladewig L Jestaedt B Misselwitz L Solymosi K Toyka G Stoll 2008 Gadofluorine M enhancement allows more sensitive detection of inflammatory CNS lesions than T2-w imaging: a quantitative MRI study Brain 131 2341 2352 10.1093/brain/awn156 10.1093/brain/awn156 18669504
25. Hebel R, Stromberg MW (1986) Anatomy and embryology of the laboratory rat. BioMed Verlag, Woerthsee
26. Burch S, Yee AJM (2005) Role of photodynamic therapy for bone metastasis. In: Singh G, Rabbani SA (eds) Bone metastasis. Humana Press Inc, Totowa, pp 243-253
27. SK Bisland L Lilge A Lin R Rusnov BC Wilson 2004 Metronomic photodynamic therapy as a new paradigm for photodynamic therapy: rationale and preclinical evaluation of technical feasibility for treating malignant brain tumors Photochem Photobiol 80 22 30 10.1562/2004-03-05-RA-100.1 10.1562/2004-03-05-RA- 100.1 1:CAS:528:DC%2BD2cXnsVeju70%3D 15339204
28. BW Henderson SO Gollnick JW Snyder TM Busch PC Kousis RT Cheney J Morgan 2004 Choice of oxygen-conserving treatment regimen determines the inflammatory response and outcome of photodynamic therapy of tumors Cancer Res 64 2120 2126 10.1158/0008-5472.CAN-03-3513 10.1158/0008-5472.CAN-03-3513 1:CAS:528: DC%2BD2cXitFCguro%3D 15026352 (Pubitemid 38339462)
29. BW Henderson TM Busch JW Snyder 2006 Fluence rate as a modulator of PDT mechanisms Lasers Surg Med 38 489 493 10.1002/lsm.20327 10.1002/lsm.20327 16615136
30. LI Grossweiner 1997 PDT light dosimetry revisited J Photochem Photobiol B 38 258 268 10.1016/S1011-1344(96)07469-6 10.1016/S1011-1344(96)07469-6 1:CAS:528:DyaK2sXjslKks7g%3D 9203389 (Pubitemid 27277887)
31. J Li TC Zhu 2008 Determination of in vivo light fluence distribution in a heterogeneous prostate during photodynamic therapy Phys Med Biol 53 2103 2114 10.1088/0031-9155/53/8/007 10.1088/0031-9155/53/8/007 18369279 (Pubitemid 351594411)
32. X Zhou BW Pogue B Chen T Hasan 2004 Analysis of effective molecular diffusion rates for verteporfin in subcutaneous versus orthotopic dunning prostate tumors Photochem Photobiol 79 323 331 10.1562/MU-03-31.1 10.1562/MU-03-31.1 1:CAS:528:DC%2BD2cXjsVyrtLk%3D 15137508
33. Cruess AF, Zlateva G, Pleil AM, Wirostko B (2008) Photodynamic therapy with verteporfin in age-related macular degeneration: a systematic review of efficacy, safety, treatment modifications and pharmacoeconomic properties. Acta Ophthalmol (Copenh). doi: 10.1111/j.1755-3768.2008.01218.x