Creation of TNFR1-selective antagonist and its therapeutic effects

Yakugaku Zasshi

Volumn 130, Issue 1, 2010, Pages 63-68

  Nomura, Tetsuya ^a,b   Abe, Yasuhiro ^b   Yoshioka, Yasuo ^a,b   Nakagawa, Shinsaku ^a   Tsunoda, Shin Ichi ^a,b   Tsutsumi, Yasuo ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

Autoimmune disease; Phage display technique; TNFR1 selective antagonist; Tumor necrosis factor (TNF )

Indexed keywords

MUTANT PROTEIN; RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 1 INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AUTOIMMUNE DISEASE; CONFERENCE PAPER; DISEASE EXACERBATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; HEPATITIS; HOST RESISTANCE; HUMAN; INFLAMMATORY DISEASE; NONHUMAN; PHAGE DISPLAY; SURVIVAL RATE; THERAPY EFFECT;

ANIMALS; AUTOIMMUNE DISEASES; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; HUMANS; MICE; MUTANT PROTEINS; PEPTIDE LIBRARY; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; TUMOR NECROSIS FACTOR-ALPHA;

EID: 74849117085     PISSN: 00316903     EISSN: 13475231     Source Type: Journal    
DOI: 10.1248/yakushi.130.63     Document Type: Conference Paper

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