An analytical method for cyclosporine using liquid chromatography-mass spectrometry

Biomedical Chromatography

Volumn 24, Issue 2, 2010, Pages 148-153

  Kanduru, Srividya V ^a   Somayaji, Vishwa ^a   Lavasanifar, Afsaneh ^a   Brocks, Dion R ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Cyclosporine; Mass spectrometry; Pharmacokinetics; Rat

Indexed keywords

AMMONIUM HYDROXIDE; BODY FLUIDS; KETONES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; RATS;

AMIODARONE; ANALYTICAL METHOD; AQUEOUS LAYER; CYCLOSPORINE; CYCLOSPORINE A; INTERNAL STANDARDS; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LIQUID-LIQUID EXTRACTION; ORGANIC LAYERS; RAT PLASMA;

METHANOL;

ACETONITRILE; AMIODARONE; CYCLOSPORIN A; ETHER; ION; METHANOL;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; DRUG STRUCTURE; EVAPORATION; FLOW RATE; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; NONHUMAN; RAT; RELIABILITY; VALIDATION STUDY;

RATTUS;

EID: 74849107195     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1263     Document Type: Article

References (20)

1. Aliabadi HM, Spencer TJ, Mahdipoor P, Lavasanifar A and Brocks DR. Insights into the effects of hyperlipoproteinemia on cyclosporine A biodistribution and relationship to renal function. The Aaps Journal 2006; 8: E672.
2. Ansermot N, Fathi M, Veuthey JL, Desmeules J, Rudaz S and Hochstrasser D. Simultaneous quantification of cyclosporine, tacrolimus, sirolimus and everolimus in whole blood by liquid chromatography-electrospray mass spectrometry. Clinical Biochemistry 2008; 41: 728.
3. Brocks DR, Ala S and Aliabadi HM. The effect of increased lipoprotein levels on the pharmacokinetics of cyclosporine A in the laboratory rat. Biopharmaceutics & Drug Disposition 2006; 27: 7.
4. Burckart GJ, Jain A, Diven W, Venkataramanan R and Starzl TE. Cyclosporine measurement by FPIA, PC-RIA, and HPLC following liver transplantation. Transplantation Proceedings 1990; 22: 1319.
5. Chimalakonda AP, Shah RB and Mehvar R. High-performance liquid chromatographic analysis of cyclosporin A in rat blood and liver using a commercially available internal standard. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2002; 772: 107.
6. Fahr A. Cyclosporin clinical pharmacokinetics. Clinical Pharmacokinetics 1993; 24: 472.
7. Ferraccioli GF,Tomietto P and De Santis M. Rationale for T cell inhibition by cyclosporin in major autoimmune diseases. Annals of the New York Academy of Sciences 2005; 1051: 658.
8. Hughes TA, Gaber AO and Montgomery CE. Plasma distribution of cyclosporine within lipoproteins and 'in vitro' transfer between very-low-density lipoproteins, low-density lipoproteins, and high-density lipoproteins. Therapeutic Drug Monitoring 1991; 13: 289.
9. Kapturczak MH, Meier-Kriesche HU and Kaplan B. Pharmacology of calcineurin antagonists. Transplantation Proceedings 2004; 36: 25S.
10. Li AC, Li Y, Guirguis MS, Caldwell RG and Shou WZ. Advantages of using tetrahydrofuran-water as mobile phases in the quantitation of cyclosporin A in monkey and rat plasma by liquid chromatographytandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 2007; 43: 277.
11. McBride JH, Rodgerson DO, Park SS and Reyes AF. Measurement of cyclosporine in plasma from patients with various transplants: HPLC radioimmunoassay with a specific monoclonal antibody compared. Clinical Chemistry 1989; 35: 1726.
12. Olyaei AJ, de Mattos AM, Bennett WM. Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies. Current Opinion in Critical Care 2001; 7: 384-389.
13. Shah VP, Midha KK, Findlay JW, Hill HM, Hulse JD, Mc Gilveray IJ, McKay G, Miller KJ, Patnaik RN, Powell ML, Tonelli A, Viswanathan CT and Yacobi A. Bioanalytical method validation- a revisit with a decade of progress. Pharmaceutical Research 2000; 17: 1551.
14. Shibata N, Inoue Y, Fukumoto K, Nishimura A, Fukushima K, Yoshikawa Y, Spiteller G and Takada K. Evaluation of factors to decrease bioavailability of cyclosporin A in rats with gentamicin-induced acute renal failure. Biological and Pharmaceutical Bulletin 2004; 27: 384.
15. Simpson J, Zhang Q, Ozaeta P and Aboleneen H. A specific method for the measurement of cyclosporin A in human whole blood by liquid chromatography- tandem mass spectrometry. Therapeutic Drug Monitoring 1998; 20: 294.
16. Steimer W. Performance & specificity of monoclonal immunoassays for cyclosporine monitoring: how specific is specific? Clinical Chemistry 1999; 45: 371.
17. Tanaka C, Kawai R and Rowland M. Dose-dependent pharmacokinetics of cyclosporin A in rats: events in tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals 2000; 28: 582.
18. Taylor AL, Watson CJ and Bradley JA. Immunosuppressive agents in solid organ transplantation: mechanisms of action and therapeutic efficacy. Critical Reviews in Oncology/Hematology 2005; 56: 23.
19. Zaater MF, Tahboub YR and Najib NM. Liquid chromatographic-electrospray mass spectrometric determination of cyclosporin A in human plasma. Analytical and Bioanalytical Chemistry 2005; 382: 223.
20. Zaghloul AA, Hussain A, Khan MA and Ahsan F. Development of a HPLC method for the determination of cyclosporin-A in rat blood and plasma using naproxen as an internal standard. Journal of Pharmaceutical and Biomedical Analysis 2003; 31: 1101.