Detection of a transient intermediate in a rapid protein folding process by solid-state nuclear magnetic resonance

Journal of the American Chemical Society

Volumn 132, Issue 1, 2010, Pages 24-25

  Hu, Kan Nian ^a   Yau, Wai Ming ^a   Tycko, Robert ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLDED STATE; FOLDING TIME; HELICAL PROTEINS; NMR DATA; NMR SPECTRUM; QUENCHING TIME; SECONDARY STRUCTURES; SOLID-STATE NMR SPECTROSCOPY; SOLID-STATE NUCLEAR MAGNETIC RESONANCE; TERTIARY STRUCTURES; TIME-RESOLVED OPTICAL TECHNIQUE; TIME-SCALES; TRANSIENT INTERMEDIATE; UNFOLDED PROTEINS;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FOLDING; QUENCHING; RESONANCE; TIME MEASUREMENT;

NUCLEAR MAGNETIC RESONANCE;

COPPER; GLYCEROL; GUANIDINE; ISOPENTANE; PROTEIN; STAINLESS STEEL; WATER;

ALPHA HELIX; ARTICLE; BLOTTING; CHEMICAL STRUCTURE; DENATURATION; FREEZING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KINETICS; MICROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLARIZATION; PROTEIN CONFORMATION; PROTEIN FOLDING; SIMULATION; SOLID STATE; SOLUTION AND SOLUBILITY; TECHNIQUE; TEMPERATURE; VELOCITY; VISCOSITY;

FREEZING; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NEUROFILAMENT PROTEINS; PEPTIDE FRAGMENTS; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 74849099434     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja908471n     Document Type: Article

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