-
1
-
-
0030993717
-
Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials
-
Newlands ES, Stevens MF, Wedge SR, Wheelhouse RT, Brock C, 1997 Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat Rev 23: 35-61.
-
(1997)
Cancer Treat Rev
, vol.23
, pp. 35-61
-
-
Newlands, E.S.1
Stevens, M.F.2
Wedge, S.R.3
Wheelhouse, R.T.4
Brock, C.5
-
2
-
-
0034005995
-
Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma
-
Agarwala SS, Kirkwood JM, 2000 Temozolomide, a novel alkylating agent with activity in the central nervous system, may improve the treatment of advanced metastatic melanoma. Oncologist 5: 144-151.
-
(2000)
Oncologist
, vol.5
, pp. 144-151
-
-
Agarwala, S.S.1
Kirkwood, J.M.2
-
3
-
-
0035469483
-
Current and future developments in the use of temozolomide for the treatment of brain tumours
-
Stupp R, Gander M, Leyvraz S, Newlands E, 2001 Current and future developments in the use of temozolomide for the treatment of brain tumours. Lancet Oncol 2: 552-560.
-
(2001)
Lancet Oncol
, vol.2
, pp. 552-560
-
-
Stupp, R.1
Gander, M.2
Leyvraz, S.3
Newlands, E.4
-
4
-
-
33644846851
-
Phase II study of temozolomide and thalidomide in patients with metastatic neuroendocrine tumors
-
Kulke MH, Stuart K, Enzinger PC, et al, 2006 Phase II study of temozolomide and thalidomide in patients with metastatic neuroendocrine tumors. J Clin Oncol 24: 401-406.
-
(2006)
J Clin Oncol
, vol.24
, pp. 401-406
-
-
Kulke, M.H.1
Stuart, K.2
Enzinger, P.C.3
-
5
-
-
33749537681
-
Longterm response of pituitary carcinoma to temozolomide. Report of two cases
-
Fadul CE, Kominsky AL, Meyer LP, et al, 2006 Longterm response of pituitary carcinoma to temozolomide. Report of two cases. J Neurosurg 105: 621-626.
-
(2006)
J Neurosurg
, vol.105
, pp. 621-626
-
-
Fadul, C.E.1
Kominsky, A.L.2
Meyer, L.P.3
-
6
-
-
33744501578
-
Temozolomide: A novel treatment for pituitary carcinoma
-
Lim S, Shahinian H, Maya MM, Yong W, Heaney AP, 2006 Temozolomide: A novel treatment for pituitary carcinoma. Lancet Oncol 7: 518-520.
-
(2006)
Lancet Oncol
, vol.7
, pp. 518-520
-
-
Lim, S.1
Shahinian, H.2
Maya, M.M.3
Yong, W.4
Heaney, A.P.5
-
7
-
-
33748799412
-
Antitumour effects of temozolomide in a man with a large, invasive prolactin-producing pituitary neoplasm
-
Syro LV, Uribe H, Penagos LC, et al, 2006 Antitumour effects of temozolomide in a man with a large, invasive prolactin-producing pituitary neoplasm. Clin Endocrinol (Oxf) 65: 552-553.
-
(2006)
Clin Endocrinol (Oxf)
, vol.65
, pp. 552-553
-
-
Syro, L.V.1
Uribe, H.2
Penagos, L.C.3
-
8
-
-
33845338456
-
Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: Morphological findings
-
Kovacs K, Horvath E, Syro LV, et al, 2007 Temozolomide therapy in a man with an aggressive prolactin-secreting pituitary neoplasm: Morphological findings. Hum Pathol 38: 185-189.
-
(2007)
Hum Pathol
, vol.38
, pp. 185-189
-
-
Kovacs, K.1
Horvath, E.2
Syro, L.V.3
-
9
-
-
34147157741
-
Temozolomide in the treatment of an invasive prolactinoma resistant to dopamine agonists
-
Neff LM, Weil M, Cole A, et al, 2007 Temozolomide in the treatment of an invasive prolactinoma resistant to dopamine agonists. Pituitary 10: 81-86.
-
(2007)
Pituitary
, vol.10
, pp. 81-86
-
-
Neff, L.M.1
Weil, M.2
Cole, A.3
-
10
-
-
58249085543
-
Treatment of Nelson's syndrome with temozolomide
-
Moyes VJ, Alusi G, Sabin HI, et al, 2009 Treatment of Nelson's syndrome with temozolomide. Eur J Endocrinol 160: 115-119.
-
(2009)
Eur J Endocrinol
, vol.160
, pp. 115-119
-
-
Moyes, V.J.1
Alusi, G.2
Sabin, H.I.3
-
11
-
-
61449125974
-
O(6)-methylguanine DNA methyltransferase immunoexpression in nonfunctioning pituitary adenomas: Are progressive tumors potential candidates for temozolomide treatment?
-
Widhalm G, Wolfsberger S, Preusser M, et al, 2009 O(6)-methylguanine DNA methyltransferase immunoexpression in nonfunctioning pituitary adenomas: Are progressive tumors potential candidates for temozolomide treatment? Cancer 115: 1070-1080.
-
(2009)
Cancer
, vol.115
, pp. 1070-1080
-
-
Widhalm, G.1
Wolfsberger, S.2
Preusser, M.3
-
12
-
-
0034928488
-
Severe lymphocytic adenohypophysitis with selective disappearance of prolactin cells: A histologic, ultrastructural and immunoelectron microscopic study
-
Horvath E, Vidal S, Syro LV, Kovacs K, Smyth HS, Uribe H, 2001 Severe lymphocytic adenohypophysitis with selective disappearance of prolactin cells: A histologic, ultrastructural and immunoelectron microscopic study. Acta Neuropathol 101: 631-637.
-
(2001)
Acta Neuropathol
, vol.101
, pp. 631-637
-
-
Horvath, E.1
Vidal, S.2
Syro, L.V.3
Kovacs, K.4
Smyth, H.S.5
Uribe, H.6
-
13
-
-
85036782279
-
-
Horvath E, Kovacs K, 1998 The adenohypophysis. In: Kovacs K, Asa SL (eds): Functional endocrine pathology, ed 2nd Malden, Blackwell; pp, 247-281.
-
Horvath E, Kovacs K, 1998 The adenohypophysis. In: Kovacs K, Asa SL (eds): Functional endocrine pathology, ed 2nd Malden, Blackwell; pp, 247-281.
-
-
-
-
14
-
-
85036794394
-
-
Horvath E, Scheithauer BW, Kovacs K, Lloyd RV, 2002 Hypothalamus and pituitary. In: Graham DI, Lantos PL (eds): Greenfield's neuropathology, ed 7th New York, NY, Arnold Publishers, 1, pp, 983-1051.
-
Horvath E, Scheithauer BW, Kovacs K, Lloyd RV, 2002 Hypothalamus and pituitary. In: Graham DI, Lantos PL (eds): Greenfield's neuropathology, ed 7th New York, NY, Arnold Publishers, vol 1, pp, 983-1051.
-
-
-
-
15
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al, 2000 Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343: 1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
16
-
-
12144291692
-
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
-
Hegi ME, Diserens AC, Godard S, et al, 2004 Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res 10: 1871-1874.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1871-1874
-
-
Hegi, M.E.1
Diserens, A.C.2
Godard, S.3
-
17
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al, 2005 MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352: 997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
18
-
-
11144349554
-
Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors
-
Mollemann M, Wolter M, Felsberg J, Collins VP, Reifenberger G 2005 Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors. Int J Cancer 113: 379-385.
-
(2005)
Int J Cancer
, vol.113
, pp. 379-385
-
-
Mollemann, M.1
Wolter, M.2
Felsberg, J.3
Collins, V.P.4
Reifenberger, G.5
-
19
-
-
33746860420
-
O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: Results from the ccg-945 cohort
-
Pollack IF, Hamilton RL, Sobol RW, et al, 2006 O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: Results from the ccg-945 cohort. J Clin Oncol 24: 3431-3437.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3431-3437
-
-
Pollack, I.F.1
Hamilton, R.L.2
Sobol, R.W.3
-
20
-
-
38149032511
-
MGMT immunoexpression predicts responsiveness of pituitary tumors to temozolomide therapy
-
Kovacs K, Scheithauer BW, Lombardero M, et al, 2008 MGMT immunoexpression predicts responsiveness of pituitary tumors to temozolomide therapy. Acta Neuropathol 115: 261-262.
-
(2008)
Acta Neuropathol
, vol.115
, pp. 261-262
-
-
Kovacs, K.1
Scheithauer, B.W.2
Lombardero, M.3
-
21
-
-
67650302290
-
Low 06-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumors
-
McCormack AI, McDonald KL, Gill AJ, 2009 Low 06-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumors. Clin Endocrinol (Oxf) 71: 226-233.
-
(2009)
Clin Endocrinol (Oxf)
, vol.71
, pp. 226-233
-
-
McCormack, A.I.1
McDonald, K.L.2
Gill, A.J.3
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