Inhibitory mechanism of novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae

Journal of Microbiology and Biotechnology

Volumn 19, Issue 12, 2009, Pages 1582-1589

  Jin, Bong Suk ^a   Han, Seong Gu ^a   Lee, Won Kyu ^a   Ryoo, Sung Weon ^b   Lee, Sang Jae ^c   Suh, Se Won ^c   Yu, Yeon Gyu ^a  

^a Kookmin University   (South Korea)

^b Korean Institute of Tuberculosis   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Cell wall synthesis; Cys117 loop; Haemophilus influenzae; Inhibitors; MurA

Indexed keywords

BACTERIAL ENZYME; CYSTEINE; EBSELEN; FOSFOMYCIN; THIOL DERIVATIVE; THIOMERSAL; THIRAM; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE ENOLPYRUVYLTRANSFERASE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; ENZYME INHIBITION; ESCHERICHIA COLI; GROWTH INHIBITION; HAEMOPHILUS INFLUENZAE; HUMAN; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM;

ALKYL AND ARYL TRANSFERASES; ANTIOXIDANTS; AZOLES; CATALYTIC DOMAIN; CELL WALL; CYSTEINE; ESCHERICHIA COLI; FUNGICIDES, INDUSTRIAL; GRAM-NEGATIVE BACTERIAL INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; ORGANOSELENIUM COMPOUNDS; PRESERVATIVES, PHARMACEUTICAL; PROTEIN CONFORMATION; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM; THIMEROSAL; THIRAM;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HAEMOPHILUS INFLUENZAE; NEGIBACTERIA; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHIMURIUM;

EID: 74749100120     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.0905.05036     Document Type: Article

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