Preparation and characterization of PMAA/MWCNTs nanohybrid hydrogels with improved mechanical properties

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 92, Issue 1, 2010, Pages 243-254

  Luo, Yan Ling ^a   Xu, Feng ^a   Feng, Qiang Suo ^a   Chen, Ya Shao ^a   Ma, Chao ^a  

^a SHAANXI NORMAL UNIVERSITY   (China)

Author keywords

Cytotoxicity; Hydrogel; Mechanical properties; Morphology; Nanomaterials

Indexed keywords

BIOLOGICAL APPLICATIONS; CHARGE TRANSFER INTERACTION; CROSSLINKER CONCENTRATION; CYTOCOMPATIBILITY; FREE RADICAL CROSSLINKING; IN-SITU; LOAD TRANSFER; METHACRYLIC ACIDS; MORPHOLOGICAL CHARACTERIZATION; MTT ASSAYS; NANO-MATERIALS; NANOHYBRIDS; PH RESPONSE; POLY (METHACRYLIC ACID); SMART HYDROGELS; SWELLING BEHAVIOR; SWELLING RATES; WELL-DISPERSED;

ACIDS; BIOLOGICAL MATERIALS; CARBON NANOTUBES; CHARACTERIZATION; CROSSLINKING; FREE RADICAL POLYMERIZATION; FREE RADICALS; HYDROGEN BONDS; MECHANICAL PROPERTIES; MORPHOLOGY; MULTIWALLED CARBON NANOTUBES (MWCN); NANOSTRUCTURED MATERIALS;

HYDROGELS;

BIOMATERIAL; CATION; FREE RADICAL; HYDROGEN; MULTI WALLED NANOTUBE; POLYELECTROLYTE; POLYMETHACRYLIC ACID;

ARTICLE; ASSAY; BIOMECHANICS; COMPRESSION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSS LINKING; EMBRYO; HUMAN; HUMAN CELL; HYDROGEL; HYDROGEN BOND; MORPHOLOGY; PARTICLE SIZE; PH; POLYMERIZATION; SURFACE PROPERTY;

CELL SURVIVAL; HYDROGELS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTUBES, CARBON; POLYMETHACRYLIC ACIDS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 74749098557     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31511     Document Type: Article

References (44)

1. Cavalieri F, Hamassi AE, Chiessi E, Paradossi G. Stable polymeric microballoons as multifunctional device for biomedical uses: Synthesis and characterization. Langmuir 2005;21:8758-8764.
2. Khutoryanskiy VV. Hydrogen-bonded interpolymer complexes as materials for pharmaceutical applications. Int J Pharmaceutics 2007;334:15-26.
3. Collett J, Crawford A, Hatton PV, Geoghegan M, Rimmer S. Thermally responsive polymeric hydrogel brushes: Synthesis, physical properties and use for the culture of chondrocytes. J R Soc Interface 2007;4:117-126.
4. Westesen K. Novel lipid-based colloidal dispersions as potential drug administration systems-expectations and reality. Colloid Polym Sci 2000;278:608-618.
5. Hemsley AR, Griffiths PC. Architecture in the microcosm: Biocolloids, self-assembly and pattern formation. Philos Trans R Soc Lond A 2000;358:547-564.
6. Lassalle V, Ferreira ML. PLA Nano- and microparticles for drug delivery: An overview of the methods of preparation. Macromol Biosci 2007;7:767-783.
7. Saravanan P, Raju MP, Alam S. A study on synthesis and properties of Ag nanoparticles immobilized polyacrylamide hydrogel composites. Mater Chem Phys 2007;103:278-282.
8. Fiorito S, Serafino A, Andreola F, Bernier P. Effects of fullerenes and single-wall carbon nanotubes on murine and human macrophages. Carbon 2006;44:1100-1105.
9. Pulskamp K, Diabaté S, Krug HF. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol Lett 2007; 168:58-74.
10. Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Curr Opin Chem Biol 2005;9: 674-679.
11. Tong X, Zheng J, Lu Y, Zhang Z, Cheng H. Swelling and mechanical behaviors of carbon nanotube/poly(vinyl alcohol) hybrid hydrogels. Mater Lett 2007;61:1704-1706.
12. Ostroha J, Pong M, Lowman A, Dan N. Controlling the collapse/swelling transition in charged hydrogels. Biomaterials 2004;25:4345-4353.
13. Lopes CMA, Felisberti MI. Mechanical behavior and biocompatibility of poly(1-vinyl-2-pyrrolidinone)-gelatin IPN hydrogels. Biomaterials 2003;24:1279-1284.
14. Xia X, Yih J, D'Souza NA, Hu Z. Swelling and mechanical behavior of poly(N-isopropylacrylamide)/Namontmorillonite layered silicates composite gels. Polymer 2003;44:3389-3393.
15. Jeon O, Song SJ, Lee KJ, Park MH, Lee SH, Hahn SK, Kim S, Kim BS. Mechanical properties and degradation behaviors of hyaluronic acid hydrogels crosslinked at various crosslinking densities. Carbonhydr Polym 2007;70:251-257.
16. Lin Z, Wu W, Wang J, Jin X. Studies on swelling behaviors, mechanical properties, network parameters and thermodynamic interaction of water sorption of 2-hydroxyethyl methacrylate/novolac epoxy vinyl ester resin copolymeric hydrogels. React Funct Polym 2007;67:789-797.
17. Devine DM, Devery SM, Lyons JG, Geever LM, Kennedy JE, Higginbotham CL. Multifunctional polyvinylpyrrolidinone-polyacrylic acid copolymer hydrogels for biomedical applications. Int J Pharm 2006;326:50-59.
18. Konyushenko EN, Stejskal J, Trchová M, Hradil J, Kovářová J, Prokeš J, Cieslar M, Hwang JY, Chen KH, Sapurina I. Multi-wall carbon nanotubes coated with polyaniline. Polymer 2006;47:5715-5723.
19. Sham ML, Kim JK. Surface functionalities of multi-wall carbon nanotubes after UV/O zone and TETA treatments. Carbon 2006;44:768-777.
20. Pielichowska K, Głowinkowski S, Lekki J, Biniaś D, Pielichowski K, Jenczyk J. PEO/fatty acid blends for thermal energy storage materials. Structural/morphological features and hydrogen interactions. Eur Polym J 2008;44:3344-3360.
21. Davey RJ, Dent G, Mughal RK, Parveen S. Concerning the relationship between structural and growth synthons in crystal nucleation: Solution and crystal chemistry of carboxylic acids as revealed through IR spectroscopy. Cryst Growth Des 2006; 6:1788-1796.
22. Zhang KP, Luo YL, Li ZQ. Synthesis and characterization of a pH- and ionic strength-responsive hydrogel. Soft Mater 2007; 5:183-195.
23. Xiong J, Zheng Z, Qin X, Li M, Li H, Wang X. The thermal and mechanical properties of a polyurethane/multi-walled carbon nanotube composite. Carbon 2006;44:2701-2707.
24. Xiong JW, Liu YH, Yang XH, Wang XL. Thermal and mechanical properties of polyurethane/montmorillonite nanocomposites based on a novel reactive modifier. Polym Degrad Stab 2004;86:549-555.
25. Haider S, Park SY, Saeed K, Farmer BL. Swelling and electroresponsive characteristics of gelatin immobilized onto multi-walled carbon nanotubes. Sens Actuators B 2007;124: 517-528.
26. Kaparissides C, Alexandridou S, Kotti K, Chaitidou S. Recent advances in novel drug delivery systems. J Nanotechnol 2006; 2:1-11.
27. Zhang XL, Zhang Y. Study on the synthesis and performance of pH and temperature responsive IPN(CS/NIPAm-co-IA). Chem Bioeng 2006;23:20-23.
28. Chen S, Liu M, Jin S, Chen Y. Synthesis and swelling properties of pH-sensitive hydrogels based on chitosan and poly(methacrylic acid) semi-interpenetrating polymer network. J Appl Polym Sci 2005;98:1720-1726.
29. Philip B, Abraham JK, Chandrasekhar A, Varadan VK. Carbon nanotube/PMMA composite thin films for gas-sensing applications. Smart Mater Struct 2003;12:935-939.
30. Jeon O, Song SJ, Lee KJ, Park MH, Lee SH, Hahn SK, Kim S, Kim BS. Mechanical properties and degradation behaviors of hyaluronic acid hydrogels crosslinked at various crosslinking densities. Carbohydr Polym 2007;70:251-257.
31. Li H, Qiang DQ, Chen HL, Liu BL, Gao LZ. A Novel Gelatin - carbon nanotubes hybrid hydrogel. Macromol Biosci 2003; 3:720-724.
32. Wang D, Chen L. Temperature and pH-responsive single-walled carbon nanotube dispersions. Nano Lett 2007;7:1480-1484.
33. Luo YL, Zhang KP, Wei QB, Liu ZQ, Chen YS. Poly(MAAco-AN) hydrogels with improved mechanical properties for theophylline controlled delivery. Acta Biomater 2009;5:316-327.
34. Rička J, Tznaka T. Swelling of ionic gels: Quantitative performance of the Donnan theory. Macromolecules 1984;17:2916-2921.
35. Chao GT, Deng HX, Huang Q, Jia WJ, Huang WX, Gu YC, Tan HP, Fan LY, Liu CB, Huang AL, Lei K, Gong CY, Tu MJ, Qian ZY. Preparation and characterization of pH sensitive semi-interpenetrating network hydrogel based on methacrylic acid, bovine serum albumin (BSA), and PEG. J Polym Res 2006;13:349-355.
36. Satish CS, Shivakumar HG. Dynamic swelling and in vitro release of insulin from semiinterpenetrating polymer networks of poly(vinyl alcohol) and poly(methacrylic acid). Ind J Pharm Sci 2007;69:58-63.
37. Kozlovskaya V, Kharlampieva E, Mansfield ML, Sukhishvili SA. Poly(methacrylic acid) hydrogel films and capsules: Response to pH and ionic strength, and encapsulation of macromolecules. Chem Mater 2006;18:328-336.
38. Lee DH, Kim JW, Suh KD. Mechanical properties of amphiphilic urethane acrylate ionomer hydrogels having heterophasic gel structure. Colloid Polym Sci 1999;277:265-269.
39. Eitan A, Fisher FT, Andrews R, Brinson LC, Schadler LS. Reinforcement mechanisms in MWCNT-filled polycarbonate. Compos Sci Technol 2006;66:1162-1173.
40. Fakhru'l-Razi A, Atieh MA, Girun N, Chuah TG, El-Sadig M, Biak DRA. Effect of multi-wall carbon nanotubes on the mechanical properties of natural rubber. Compos Struct 2006; 75:496-500.
41. Dror Y, Salalha W, Pyckhout-Hintzen W, Yarin AL, Zussman E, Cohen Y. From carbon nanotube dispersion to composite nanofibers. Prog Colloid Polym Sci 2005;130:64-69.
42. Tew GN, Sanabria-DeLong N, Agrawal SK, Bhatia SR. New properties from PLA - PEO - PLA hydrogels. Soft Matter 2005; 1:253-258.
43. Draye JP, Delaey B, Voorde AV, Bulcke AVD, Reu BD, Schacht E. In vitro and in vivo biocompatibility of dextran dialdehyde crosslinked gelatin hydrogel films. Biomaterials 1998;19:1677-1687.
44. Abarrategi A, Gutiérrez MC, Moreno-Vicente C, Hortigüela MJ, Ramos V, López-Lacomba JL, Ferrer ML, Monte F. Multiwall carbon nanotube scaffolds for tissue engineering purposes. Biomaterials 2008;29:94-102.