In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans

Experimental and Clinical Endocrinology and Diabetes

Volumn 113, Issue 7, 2005, Pages 388-395

  Schneider, Stephan ^a   Feilen, P J ^b   Schreckenberger, M ^b   Schwanstecher, M ^c   Schwanstecher, C ^c   Buchholz, H G ^b   Thews, O ^b   Oberholzer, K ^b   Korobeynikov, A ^b   Bauman, A ^b   Comagic, S ^b   Piel, M ^b   Schirrmacher, E ^b   Shiue, C Y ^d   Alavi, A A ^d   Bartenstein, P ^b   Rosch F ^b   Weber, M M ^b   Klein, H H ^a   Schirrmacher, R ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

^c TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Glibenclamide derivatives; Pancreatic islet cell mass; Sulfonylurea receptor 1

Indexed keywords

FLUORINE; GLIBENCLAMIDE; SULFONYLUREA; TECHNETIUM 99M;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INSULIN RELEASE; ISOTOPE LABELING; LIPOPHILICITY; NON INVASIVE MEASUREMENT; NONHUMAN; PANCREAS ISLET CELL TUMOR; PLASMA PROTEIN BINDING; PRIORITY JOURNAL;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DIABETES MELLITUS; FLUORINE RADIOISOTOPES; GLYBURIDE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; ISLETS OF LANGERHANS; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DRUG; TECHNETIUM;

EID: 23044456342     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-865711     Document Type: Article

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