Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic. Example: Furan (CAS No. 110-00-9)

Food and Chemical Toxicology

Volumn 48, Issue SUPPL. 1, 2010, Pages

  Carthew, Philip ^a   DiNovi, Michael ^b   Setzer, R Woodrow ^c  

^a UNILEVER RESEARCH   (United Kingdom)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Furan; Margin of exposure; MoE

Indexed keywords

FURAN;

ARTICLE; BILE DUCT CARCINOMA; CARCINOGENICITY; DOSE RESPONSE; FOOD POISONING; GENOTOXICITY; HUMAN; LIVER CELL CARCINOMA; MARGIN OF EXPOSURE; NONHUMAN; RODENT; TOXICITY TESTING;

ANIMALS; CARCINOGENS; DATA INTERPRETATION, STATISTICAL; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FOOD CONTAMINATION; FURANS; HUMANS; MALE; MICE; MODELS, STATISTICAL; MUTAGENS; RATS;

RODENTIA;

EID: 74549214612     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.10.017     Document Type: Article

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