Characteristics and Potential Functions of Human Milk Adiponectin

Journal of Pediatrics

Volumn 156, Issue 2 SUPPL., 2010, Pages

  Newburg, David S ^a   Woo, Jessica G ^b   Morrow, Ardythe L ^b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; INSULIN; LEPTIN; MILK PROTEIN; OLIGOMER;

ARTICLE; BIOLOGICAL ACTIVITY; BODY MASS; BREAST; BREAST FEEDING; BREAST MILK; CIRCULATION; ENTERITIS; ENVIRONMENT; FATTY ACID METABOLISM; GLYCOSYLATION; HORMONE BLOOD LEVEL; HUMAN; IMMUNOMODULATION; INFLAMMATION; INSULIN SENSITIVITY; INTESTINE ABSORPTION; INTESTINE MUCOSA; LACTATION; METABOLIC REGULATION; METABOLISM; MILK LEVEL; MOLECULAR WEIGHT; OBESITY; OVARY INFLAMMATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; WEIGHT GAIN;

ADIPONECTIN; ADIPOSITY; BODY WEIGHT; CHILD DEVELOPMENT; FEMALE; HUMANS; INFANT; MILK, HUMAN;

EID: 74549168920     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2009.11.020     Document Type: Article

References (30)

1. Berg A.H., Combs T.P., and Scherer P.E. ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13 (2002) 84-89
2. Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7 (2001) 941-946
3. Arita Y., Kihara S., Ouchi N., Takahashi M., Maeda K., Miyagawa J., et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257 (1999) 79-83
4. Matsubara M., Maruoka S., and Katayose S. Decreased plasma adiponectin concentrations in women with dyslipidemia. J Clin Endocrinol Metab 87 (2002) 2764-2769
5. Matsuda M., Shimomura I., Sata M., Arita Y., Nishida M., Maeda N., et al. Role of adiponectin in preventing vascular stenosis: the missing link of adipo-vascular axis. J Biol Chem 277 (2002) 37487-37491
6. Weyer C., Funahashi T., Tanaka S., Hotta K., Matsuzawa Y., Pratley R.E., et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86 (2001) 1930-1935
7. Fisher F.F., Trujillo M.E., Hanif W., Barnett A.H., McTernan P.G., Scherer P.E., et al. Serum high molecular weight complex of adiponectin correlates better with glucose tolerance than total serum adiponectin in Indo-Asian males. Diabetologia 48 (2005) 1084-1087
8. Pajvani U.B., Hawkins M., Combs T.P., Rajala M.W., Doebber T., Berger J.P., et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 279 (2004) 12152-12162
9. Itoh H., Itakura A., Kurauchi O., Okamura M., Nakamura H., and Mizutani S. Hepatocyte growth factor in human breast milk acts as a trophic factor. Horm Metab Res 34 (2002) 16-20
10. Takahata Y., Takada H., Nomura A., Nakayama H., Ohshima K., and Hara T. Detection of interferon-gamma-inducible chemokines in human milk. Acta Paediatr 92 (2003) 659-665
11. Tregoat V., Montagne P., Bene M.C., and Faure G. Changes in the mannan binding lectin (MBL) concentration in human milk during lactation. J Clin Lab Anal 16 (2002) 304-307
12. Chowanadisai W., Kelleher S.L., Nemeth J.F., Yachetti S., Kuhlman C.F., Jackson J.G., et al. Detection of a single nucleotide polymorphism in the human alpha-lactalbumin gene: implications for human milk proteins. J Nutr Biochem 16 (2005) 272-278
13. Guerra S., Carla Lohman I., LeVan T.D., Wright A.L., Martinez F.D., and Halonen M. The differential effect of genetic variation on soluble CD14 levels in human plasma and milk. Am J Reprod Immunol 52 (2004) 204-211
14. Uysal F.K., Onal E.E., Aral Y.Z., Adam B., Dilmen U., and Ardicolu Y. Breast milk leptin: its relationship to maternal and infant adiposity. Clin Nutr 21 (2002) 157-160
15. Aydin S., Aydin S., Ozkan Y., and Kumru S. Ghrelin is present in human colostrum, transitional and mature milk. Peptides 27 (2006) 878-882
16. Martin L.J., Woo J.G., Geraghty S.R., Altaye M., Davidson B.S., Banach W., et al. Adiponectin is present in human milk and is associated with maternal factors. Am J Clin Nutr 83 (2006) 1106-1111
17. Henderson T.R., Hamosh M., Armand M., Mehta N.R., and Hamosh P. Gastric proteolysis in preterm infants fed mother's milk or formula. Adv Exp Med Biol 501 (2001) 403-408
18. Lonnerdal B. Nutritional and physiologic significance of human milk proteins. Am J Clin Nutr 77 (2003) 1537S-1543S
19. Hamosh M. Digestion in the newborn. Clin Perinatol 23 (1996) 191-209
20. Shehadeh N., Khaesh-Goldberg E., Shamir R., Perlman R., Sujov P., Tamir A., et al. Insulin in human milk: postpartum changes and effect of gestational age. Arch Dis Child Fetal Neonatal Ed 88 (2003) F214-F216
21. Shulman R.J. Oral insulin increases small intestinal mass and disaccharidase activity in the newborn miniature pig. Pediatr Res 28 (1990) 171-175
22. Zhou Y., Sun X., Jin L., Stringfield T., Lin L., and Chen Y. Expression profiles of adiponectin receptors in mouse embryos. Gene Expr Patterns 5 (2005) 711-715
23. Bobbert T., Rochlitz H., Wegewitz U., Akpulat S., Mai K., Weickert M.O., et al. Changes of adiponectin oligomer composition by moderate weight reduction. Diabetes 54 (2005) 2712-2719
24. Marinaro J.A., Neumann G.M., Russo V.C., Leeding K.S., and Bach L.A. O-glycosylation of insulin-like growth factor (IGF) binding protein-6 maintains high IGF-II binding affinity by decreasing binding to glycosaminoglycans and susceptibility to proteolysis. Eur J Biochem 267 (2000) 5378-5386
25. van Berkel P.H.C., Geerts M.E.J., van Veen H.A., Kooiman P.M., Pieper R.R., de Boer H.A., et al. Glycosylated and unglycosylated human lactoferrins both bind iron and show identical affinities towards human lysozyme and bacterial lipopolysaccharide, but differ in their susceptibilities towards tryptic proteolysis. Biochem J 312 (1995) 107-114
26. Wang Y., Xu A., Knight C., Xu L.Y., and Cooper G.J. Hydroxylation and glycosylation of the four conserved lysine residues in the collagenous domain of adiponectin: potential role in the modulation of its insulin-sensitizing activity. J Biol Chem 277 (2002) 19521-19529
27. Odden N., and Morkrid L. High molecular weight adiponectin dominates in cord blood of newborns but is unaffected by pre-eclamptic pregnancies. Clin Endocrinol (Oxf) 67 (2007) 891-896
28. Asayama K., Hayashibe H., Dobashi K., Uchida N., Nakane T., Kodera K., et al. Decrease in serum adiponectin level due to obesity and visceral fat accumulation in children. Obes Res 11 (2003) 1072-1079
29. Stefan N., Bunt J.C., Salbe A.D., Funahashi T., Matsuzawa Y., and Tataranni P.A. Plasma adiponectin concentrations in children: relationships with obesity and insulinemia. J Clin Endocrinol Metab 87 (2002) 4652-4656
30. Buescher E.S. Anti-inflammatory characteristics of human milk: how, where, why. Adv Exp Med Biol 501 (2001) 207-222