Defining a visual marker of osteoprogenitor cells within the periodontium

Journal of Periodontal Research

Volumn 45, Issue 1, 2010, Pages 60-70

  San Miguel, S M ^a   Fatahi, M R ^a   Li, H ^a   Igwe, J C ^a   Aguila, H L ^a   Kalajzic, I ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Dental follicle; Osteoprogenitor cell; Periodontal ligament; Smooth muscle alpha actin

Indexed keywords

ACTIN; ALKALINE PHOSPHATASE; BIOLOGICAL MARKER; DIAGNOSTIC AGENT; DMP1 PROTEIN, RAT; GREEN FLUORESCENT PROTEIN; INTEGRIN BINDING SIALOPROTEIN; INTEGRIN-BINDING SIALOPROTEIN; LUMINESCENT AGENT; LY ANTIGEN; MEMBRANE PROTEIN; OSTEOCALCIN; PHOSPHOPROTEIN; RNA; SCLEROPROTEIN; SIALOGLYCOPROTEIN; SMOOTH MUSCLE ACTIN, RAT; THY 1 ANTIGEN;

ANIMAL; ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; JAW; MOUSE; ODONTOBLAST; OSTEOCYTE; PERIODONTAL LIGAMENT; PERIODONTIUM; PHENOTYPE; PHYSIOLOGY; STEM CELL; TOOTH ROOT; TOOTH SAC; TRANSGENIC MOUSE;

ACTINS; ALKALINE PHOSPHATASE; ALVEOLAR PROCESS; ANIMALS; ANTIGENS, LY; ANTIGENS, THY-1; BIOLOGICAL MARKERS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL PROLIFERATION; DENTAL SAC; EXTRACELLULAR MATRIX PROTEINS; GREEN FLUORESCENT PROTEINS; LUMINESCENT AGENTS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; ODONTOBLASTS; OSTEOCALCIN; OSTEOCYTES; OSTEOGENESIS; PERIODONTAL LIGAMENT; PERIODONTIUM; PHENOTYPE; PHOSPHOPROTEINS; RNA; SIALOGLYCOPROTEINS; STEM CELLS; TOOTH APEX;

EID: 74549135645     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2009.01201.x     Document Type: Article

References (44)

1. Gay IC, Chen S, MacDougall M. Isolation and characterization of multipotent human periodontal ligament stem cells. Orthod Craniofac Res 2007 10 : 149 160.
2. Ivanovski S, Gronthos S, Shi S, Bartold PM. Stem cells in the periodontal ligament. Oral Dis 2006 12 : 358 363.
3. Seo BM, Miura M, Gronthos S et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 2004 364 : 149 155.
4. MacNeil RL, Somerman MJ. Development and regeneration of the periodontium: parallels and contrasts. Periodontol 2000 1999 19 : 8 20.
5. Bosshardt DD. Are cementoblasts a subpopulation of osteoblasts or a unique phenotype? J Dent Res 2005 84 : 390 406.
6. Zeichner-David M. Regeneration of periodontal tissues: cementogenesis revisited. Periodontol 2000 2006 41 : 196 217.
7. Thesleff I, Nieminen P. Tooth morphogenesis and cell differentiation. Curr Opin Cell Biol 1996 8 : 844 850.
8. Melcher AH. Cells of periodontium: their role in the healing of wounds. Ann R Coll Surg Engl 1985 67 : 130 131.
9. Ten Cate AR. The development of the periodontium - a largely ectomesenchymally derived unit. Periodontol 2000 1997 13 : 9 19.
10. Hou LT, Liu CM, Chen YJ et al. Characterization of dental follicle cells in developing mouse molar. Arch Oral Biol 1999 44 : 759 770.
11. Luan X, Ito Y, Dangaria S, Diekwisch TG. Dental follicle progenitor cell heterogeneity in the developing mouse periodontium. Stem Cells Dev 2006 15 : 595 608.
12. Shi S, Bartold PM, Miura M, Seo BM, Robey PG, Gronthos S. The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthod Craniofac Res 2005 8 : 191 199.
13. Nohutcu RM, McCauley LK, Koh AJ, Somerman MJ. Expression of extracellular matrix proteins in human periodontal ligament cells during mineralization in vitro. J Periodontol 1997 68 : 320 327.
14. Lekic P, Rojas J, Birek C, Tenenbaum H, McCulloch CA. Phenotypic comparison of periodontal ligament cells in vivo and in vitro. J Periodontal Res 2001 36 : 71 79.
15. Hou LT, Liu CM, Lei JY, Wong MY, Chen JK. Biological effects of cementum and bone extracts on human periodontal fibroblasts. J Periodontol 2000 71 : 1100 1109.
16. Lin DG, Kenny DJ, Barrett EJ, Lekic P, McCulloch CA. Storage conditions of avulsed teeth affect the phenotype of cultured human periodontal ligament cells. J Periodontal Res 2000 35 : 42 50.
17. Saito Y, Yoshizawa T, Takizawa F et al. A cell line with characteristics of the periodontal ligament fibroblasts is negatively regulated for mineralization and Runx2/Cbfa1/Osf2 activity, part of which can be overcome by bone morphogenetic protein-2. J Cell Sci 2002 115 : 4191 4200.
18. Gronthos S, Mrozik K, Shi S, Bartold PM. Ovine periodontal ligament stem cells: isolation, characterization, and differentiation potential. Calcif Tissue Int 2006 79 : 310 317.
19. Duarte WR, Iimura T, Takenaga K, Ohya K, Ishikawa I, Kasugai S. Extracellular role of S100A4 calcium-binding protein in the periodontal ligament. Biochem Biophys Res Commun 1999 255 : 416 420.
20. Lin NH, Menicanin D, Mrozik K, Gronthos S, Bartold PM. Putative stem cells in regenerating human periodontium. J Periodontal Res 2008 43 : 514 523.
21. Miura M, Gronthos S, Zhao M et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 2003 100 : 5807 5812.
22. Hosoya A, Nakamura H, Ninomiya T et al. Immunohistochemical localization of alpha-smooth muscle actin during rat molar tooth development. J Histochem Cytochem 2006 54 : 1371 1378.
23. Kalajzic Z, Li H, Wang LP et al. Use of an alpha-smooth muscle actin GFP reporter to identify an osteoprogenitor population. Bone 2008 43 : 501 510.
24. Yokota T, Kawakami Y, Nagai Y et al. Bone marrow lacks a transplantable progenitor for smooth muscle type alpha-actin-expressing cells. Stem cells (Dayton, OH) 2006 24 : 13 22.
25. Maeda S, Sutliff RL, Qian J et al. Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility. Endocrinology 1999 140 : 1815 1825. (Pubitemid 29149254)
26. Kalajzic I, Braut A, Guo D et al. Dentin matrix protein 1 expression during osteoblastic differentiation, generation of an osteocyte GFP-transgene. Bone 2004 35 : 74 82.
27. D'Errico JA, Ouyang H, Berry JE et al. Immortalized cementoblasts and periodontal ligament cells in culture. Bone 1999 25 : 39 47.
28. Kalajzic I, Staal A, Yang WP et al. Expression profile of osteoblast lineage at defined stages of differentiation. J Biol Chem 2005 280 : 24618 24626.
29. Chen SC, Marino V, Gronthos S, Bartold PM. Location of putative stem cells in human periodontal ligament. J Periodontal Res 2006 41 : 547 553.
30. Kemoun P, Laurencin-Dalicieux S, Rue J et al. Localization of STRO-1, BMP-2/-3/-7, BMP receptors and phosphorylated Smad-1 during the formation of mouse periodontium. Tissue Cell 2007 39 : 257 266.
31. Sacchetti B, Funari A, Michienzi S et al. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007 131 : 324 336.
32. Doherty MJ, Ashton BA, Walsh S, Beresford JN, Grant ME, Canfield AE. Vascular pericytes express osteogenic potential in vitro and in vivo. J Bone Miner Res 1998 13 : 828 838.
33. Farrington-Rock C, Crofts NJ, Doherty MJ, Ashton BA, Griffin-Jones C, Canfield AE. Chondrogenic and adipogenic potential of microvascular pericytes. Circulation 2004 110 : 2226 2232.
34. Zannettino AC, Paton S, Arthur A et al. Multipotential human adipose-derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo. J Cell Physiol 2008 214 : 413 421.
35. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 2000 97 : 13625 13630.
36. Tsukamoto Y, Fukutani S, Shin-Ike T et al. Mineralized nodule formation by cultures of human dental pulp-derived fibroblasts. Arch Oral Biol 1992 37 : 1045 1055.
37. Takeda T, Tezuka Y, Horiuchi M et al. Characterization of dental pulp stem cells of human tooth germs. J Dent Res 2008 87 : 676 681.
38. Zheng L, Iohara K, Ishikawa M et al. Runx3 negatively regulates Osterix expression in dental pulp cells. Biochem J 2007 405 : 69 75.
39. Van Vlasselaer P, Falla N, Snoeck H, Mathieu E. Characterization and purification of osteogenic cells from murine bone marrow by two-color cell sorting using anti-Sca-1 monoclonal antibody and wheat germ agglutinin. Blood 1994 84 : 753 763.
40. Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science (New York, NY) 1988 241 : 58 62.
41. Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol 2002 245 : 42 56.
42. Foster BL, Popowics TE, Fong HK, Somerman MJ. Advances in defining regulators of cementum development and periodontal regeneration. Curr Top Dev Biol 2007 78 : 47 126.
43. Pryce BA, Brent AE, Murchison ND, Tabin CJ, Schweitzer R. Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene. Dev Dyn 2007 236 : 1677 1682.
44. Brent AE, Schweitzer R, Tabin CJ. A somitic compartment of tendon progenitors. Cell 2003 113 : 235 248.