Poor ovarian response in patients younger than 35 years: Is it also a qualitative decline in ovarian function

Human Fertility

Volumn 12, Issue 3, 2009, Pages 160-165

  Figueira, Rita De Cássia Sávio ^a   Braga, Daniela Paes Almeida Ferreira ^a,b   Nichi, Marcílio ^c   Madaschi, Camila ^a   Semião Francisco, Luciana ^a   Iaconelli Jr , Assumpto ^a   Borges Jr , Edson ^a,b  

^a Fertility Assisted Fertilization Center   (Brazil)

^b Educational and Research Center in Assisted Reproduction   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

ICSI; Oocyte retrieval; Ovarian stimulation

Indexed keywords

ESTRADIOL; GONADOTROPIN;

ABORTION; ADULT; ARTICLE; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION; HUMAN; IMPLANTATION; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; OOCYTE; OVARY FUNCTION; PREGNANCY RATE;

ADULT; AGING; CHI-SQUARE DISTRIBUTION; CHORIONIC GONADOTROPIN; EMBRYO IMPLANTATION; EMBRYO TRANSFER; ESTRADIOL; FEMALE; HUMANS; OOCYTE RETRIEVAL; OOCYTES; OVARY; OVULATION INDUCTION; PREGNANCY; PREGNANCY RATE; RETROSPECTIVE STUDIES; SPERM INJECTIONS, INTRACYTOPLASMIC;

EID: 74549134663     PISSN: 14647273     EISSN: 17428149     Source Type: Journal    
DOI: 10.1080/14647270902942928     Document Type: Article

References (42)

1. Bourgain, C. & Devroey, P. (2003). The endometrium in stimulated cycles for IVF. Human Reproduction Update, 9, 515-522.
2. Check, J. H. (1999). Low and high responders - at what levels of serum estradiol do things start to get fuzzy? Fertility & Sterility, 71, 582-583; author reply 584-586.
3. Check, J. H., Nazari, P., Check, M. L., Choe, J. K., & Liss, J. R. (2002). Prognosis following in vitro fertilization-embryo transfer (IVF-ET) in patients with elevated day 2 or 3 serum follicle stimulating hormone (FSH) is better in younger vs older patients. Clinical and Experimental Obstetrics& Gynecology, 29, 42-44.
4. De Sutter, P. & Dhont, M. (2003). Poor response after hormonal stimulation for in vitro fertilization is not related to ovarian aging. Fertility & Sterility, 79, 1294-1298.
5. El-Toukhy, T., Khalaf, Y., Hart, R., Taylor, A., & Braude, P. (2002). Young age does not protect against the adverse effects of reduced ovarian reserve - an eight year study. Human Reproduction, 17, 1519-1524.
6. Eldar-Geva, T., Brooks, B., Margalioth, E. J., Zylber-Haran, E., Gal, M., & Silber, S. J. (2003). Successful pregnancy and delivery after calcium ionophore oocyte activation in a normozoospermic patient with previous repeated failed fertilization after intracytoplasmic sperm injection. Fertility & Sterility, 79 (Suppl 3), 1656-1658.
7. Esposito, M. A., Coutifaris, C., & Barnhart, K. T. (2002). A moderately elevated day 3 FSH concentration has limited predictive value, especially in younger women. Human Reproduction, 17, 118-123.
8. Faddy, M. J., Gosden, R. G., Gougeon, A., Richardson, S. J., & Nelson, J. F. (1992). Accelerated disappearance of ovarian follicles in mid-life: implications for forecasting menopause. Human Reproduction, 7, 1342-1346.
9. Garcia, J. E., Jones, G. S., Acosta, A. A., & Wright, G. Jr. (1983). Human menopausal gonadotropin/human chorionic gonadotropin follicular maturation for oocyte aspiration: phase I, 1981. Fertility & Sterility, 39, 167-173.
10. Gougeon, A. (1996). Regulation of ovarian follicular development in primates: facts and hypotheses. Endocrine Reviews, 17, 121-155.
11. Greb, R. R., Behre, H. M., & Simoni, M. (2005). Pharmacogenetics in ovarian stimulation - current concepts and future options. Reproductive Biomedicine Online, 11, 589-600.
12. Hanoch, J., Lavy, Y., Holzer, H., Hurwitz, A., Simon, A., Revel, A., et al. (1998). Young low responders protected from untoward effects of reduced ovarian response. Fertility & Sterility, 69, 1001-1004.
13. Karande, V. C., Jones, G. S., Veeck, L. L., & Muasher, S. J. (1990). High-dose follicle-stimulating hormone stimulation at the onset of the menstrual cycle does not improve the in vitro fertilization outcome in low-responder patients. Fertility & Sterility, 53, 486-489.
14. Keay, S. D., Liversedge, N. H., & Jenkins, J. M. (1998). Could ovarian infection impair ovarian response to gonadotrophin stimulation? British Journal of Obstetrics and Gynaecology, 105, 252-253.
15. Kumbak, B., Ulug, U., Erzik, B., Akbas, H., & Bahceci, M. (2009). Early clinical pregnancy loss rate in poor responder patients does not change compared to age-matched normoresponders. Fertility & Sterility, 91, 106-109.
16. Lambalk, C. B. (2003). Value of elevated basal follicle-stimulating hormone levels and the differential diagnosis during the diagnostic subfertility work-up. Fertility & Sterility, 79, 489-490.
17. Land, J. A., Yarmolinskaya, M. I., Dumoulin, J. C., & Evers, J. L. (1996). High-dose human menopausal gonadotropin stimulation in poor responders does not improve in vitro fertilization outcome. Fertility & Sterility, 65, 961-965.
18. Lashen, H., Ledger, W., Lopez-Bernal, A., & Barlow, D. (1999). Poor responders to ovulation induction: is proceeding to in vitro fertilization worthwhile? Human Reproduction, 14, 964-969.
19. Loverro, G., Nappi, L., Mei, L., Giacomoantonio, L., Carriero, C., & Tartagni,M. (2003). Evaluation of functional ovarian reserve in 60 patients. Reproductive Biomedicine Online, 7, 200-204.
20. Martinez, F., Barri, P. N., Coroleu, B., Tur, R., Sorsa-Leslie, T., Harris, W. J., et al. (2002). Women with poor response to IVF have lowered circulating gonadotrophin surge-attenuating factor (GnSAF) bioactivity during spontaneous and stimulated cycles. Human Reproduction, 17, 634-640.
21. Nargund, G. & Bromhan, D. (1995). Comparison of endocrinological and clinical profiles and outcome of IVF cycles in patients with one ovary and two ovaries. Journal of Assisted Reproduction & Genetics, 12, 458-460.
22. Nikolaou, D., Lavery, S., Turner, C., Margara, R., & Trew, G. (2002). Is there a link between an extremely poor response to ovarian hyperstimulation and early ovarian failure? Human Reproduction, 17, 1106-1111.
23. Palermo, G., Joris, H., Devroey, P., & Van Steirteghem, A. C. (1992). Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet, 340, 17-18.
24. Rombauts, L., Suikkari, A. M.,MacLachlan, V., Trounson, A. O., & Healy, D. L. (1998). Recruitment of follicles by recombinant human follicle-stimulating hormone commencing in the luteal phase of the ovarian cycle. Fertility & Sterility, 69, 665-669.
25. Salgado Jacobo, M. I., Tovar Rodriguez, J. M., Hernandez Marin, I., & Ayala Ruiz, A. R. (2003). Frequency of altered male factor in an infertility clinic. Ginecologia Y Obstetricia de Mexico, 71, 233-237.
26. Saunders, C. M., Swann, K., & Lai F. A. (2007). PLCzeta, a sperm-specific PLC and its potential role in fertilization. Biochemical Society Symposia, 23-36.
27. Sharara, F. I., Beatse, S. N., Leonardi,M. R., Navot, D.,&Scott, R. T. Jr. (1994). Cigarette smoking accelerates the development of diminished ovarian reserve as evidenced by the clomiphene citrate challenge test. Fertility & Sterility, 62, 257-262.
28. Simon,C.,Cano, F.,Valbuena, D.,Remohí, J.,&Pellicer,A. (1995). Clinical evidence for a detrimental effect on uterine receptivity of high serum oestradiol concentrations in high and normal responder patients. Human Reproduction, 10, 2432-2437.
29. Sousa, M. & Tesarik, J. (1994). Ultrastructural analysis of fertilization failure after intracytoplasmic sperm injection. Human Reproduction, 9, 2374-2380.
30. Surrey, E. S., Bower, J., Hill, D. M., Ramsey, J., & Surrey, M. W. (1998). Clinical and endocrine effects of a microdose GnRH agonist flare regimen administered to poor responders who are undergoing in vitro fertilization. Fertility&Sterility, 69, 419-424.
31. Surrey, E. S. & Schoolcraft, W. B. (2000). Evaluating strategies for improving ovarian response of the poor responder undergoing assisted reproductive techniques. Fertility&Sterility, 73, 667-676.
32. Swann, K., Saunders, C. M., Rogers, N. T., & Lai, F. A. (2006). PLCzeta(zeta): a sperm protein that triggers Ca2+oscillations and egg activation in mammals. Seminars in Cell & Developmental Biology, 17, 264-273.
33. Tarlatzis, B. C., Zepiridis, L., Grimbizis, G., & Bontis, J. (2003). Clinical management of low ovarian response to stimulation for IVF: a systematic review. Human Reproduction Update, 9, 61-76.
34. Templeton, A., Morris, J. K. & Parslow, W. (1996). Factors that affect outcome of in-vitro fertilisation treatment. Lancet, 348, 1402-1406.
35. Tesarik, J., Kopecny, V., Plachot, M., & Mandelbaum, J. (1986). Activation of nucleolar and extranucleolar RNA synthesis and changes in the ribosomal content of human embryos developing in vitro. Journal of Reproduction & Fertility, 78, 463-470.
36. Tesarik, J., Kopecny, V., Plachot, M., & Mandelbaum, J. (1988). Early morphological signs of embryonic genome expression in human preimplantation development as revealed by quantitative electron microscopy. Developmental Biology, 128, 15-20.
37. Ubaldi, F. M., Rienzi, L., Ferrero, S., Baroni, E., Sapienza, F., Cobellis, L., et al. (2005). Management of poor responders in IVF. Reproductive Biomedicine Online, 10, 235-246.
38. Ulug, U., Ben-Shlomo, I., Turan, E., Erden, H. F., Akman, M. A., & Bahceci, M. (2003). Conception rates following assisted reproduction in poor responder patients: a retrospective study in 300 consecutive cycles. Reproductive Biomedicine Online, 6, 439-443.
39. van der Gaast, M. H., Eijkemans, M. J., van der Net, J. B., de Boer, E. J., Burger, C. W., et al. (2006). Optimum number of oocytes for a successful first IVF treatment cycle. Reproductive Biomedicine Online, 13, 476-480.
40. van Rooij, I. A., Bancsi, L. F., Broekmans, F. J., Looman, C. W., Habbema, J. D., & te Velde, E. R. (2003). Women older than 40 years of age and those with elevated follicle-stimulating hormone levels differ in poor response rate and embryo quality in in vitro fertilization. Fertility & Sterility, 79, 482-488.
41. Wardle, P. G., Mitchell, J. D., McLaughlin, E. A., Ray, B. D., McDermott, A., & Hull, M. G. (1985). Endometriosis and ovulatory disorder: reduced fertilisation in vitro compared with tubal and unexplained infertility. Lancet, 2, 236-239.
42. Zeleznik, A. J., Schuler, H. M., & Reichert, L. E. Jr. (1981). Gonadotropin-binding sites in the rhesus monkey ovary: role of the vasculature in the selective distribution of human chorionic gonadotropin to the preovulatory follicle. Endocrinology, 109, 356-362.