Modeling of the 5′-deiodination of thyroxine by iodothyronine deiodinase: Chemical corroboration of a selenenyl iodide intermediate

Angewandte Chemie - International Edition

Volumn 49, Issue 3, 2010, Pages 545-547

  Goto, Kei ^a   Sonoda, Daiju ^b   Shimada, Keiichi ^b   Sase, Shohei ^a   Kawashima, Takayuki ^b  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Enzyme models; Iodine; Reactive intermediates; Selenium; Steric hindrance

Indexed keywords

CATALYTIC CYCLES; CHEMICAL PROCESS; DEIODINATION; ENZYME MODELS; IODOTHYRONINE; MOLECULAR CAVITY; REACTIVE INTERMEDIATE; REACTIVE INTERMEDIATES; STERIC HINDRANCES;

CHEMICAL REACTIONS; INDUSTRIAL CHEMICALS; IODINE; REACTION INTERMEDIATES; SELENIUM;

ENZYMES;

IODIDE; IODIDE PEROXIDASE; SELENIUM; THYROXINE;

ARTICLE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY;

IODIDE PEROXIDASE; IODIDES; MODELS, BIOLOGICAL; MOLECULAR STRUCTURE; SELENIUM; THYROXINE;

EID: 74549131806     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200905796     Document Type: Article

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