Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the rapid simultaneous quantification of aconitine, mesaconitine, and hypaconitine in rat plasma after oral administration of sini decoction

Journal of Analytical Toxicology

Volumn 33, Issue 9, 2009, Pages 588-594

  He, Lei Ping ^a   Di, Bin ^a   Du, Ying Xiang ^a   Yan, Fang ^a   Su, Meng Xiang ^a   Liu, Hua Qing ^a   You, Lin Jun ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACONITINE; AMMONIUM ACETATE; AMMONIUM HYDROXIDE; CITALOPRAM; FORMIC ACID; GINSENG EXTRACT; HYPACONITINE; MESACONITINE; METHANOL; SINI DECOCTION; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHINESE MEDICINE; DRUG BLOOD LEVEL; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

RATTUS;

EID: 74549115257     PISSN: 01464760     EISSN: 01464760     Source Type: Journal    
DOI: 10.1093/jat/33.9.588     Document Type: Article

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